Expression of transforming growth factor alpha and epidermal growth factor receptor in human hepatocellular carcinoma

Primary carcinoma of the liver.A study of 100 cases among 48,900 necropsies

1954 • 2,755 citations

Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors.

1987 • 895 citations

A CLASSIFICATION OF CHRONIC HEPATITIS

1968 • 856 citations

TGFα overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

1990 • 714 citations

Transforming growth factor α

1988 • 707 citations

The tnm classification of malignant tumors

1988 • 544 citations

Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism.

1989 • 528 citations

Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha.

1992 • 500 citations

INTRODUCTION

1982 • 390 citations

Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model.

1987 • 222 citations

Transforming growth factor alpha and epidermal growth factor in human pancreatic cancer

1991 • 213 citations

Immunohistochemical evidence of autocrine growth factors in adenocarcinoma of the human lung.

1990 • 174 citations

Developmental Expression of Rat Transforming Growth Factor-α mRNA

1985 • 147 citations

Acute and chronic hepatitis revisited. Review by an international group.

1977 • 147 citations

Transforming Growth Factor Alpha Dramatically Enhances Oncogene-Induced Carcinogenesis in Transgenic Mouse Pancreas and Liver

1993 • 131 citations

Elevation of transforming growth factor alpha and its relationship to the epidermal growth factor and alpha-fetoprotein levels in patients with hepatocellular carcinoma.

1987 • 129 citations

Developmental expression of rat transforming growth factor-alpha mRNA.

1985 • 114 citations

Regulation of transforming growth factor expression in rat intestinal epithelial cell lines.

1991 • 109 citations

Immunoreactivity of transforming growth factor alpha in the normal adult gastrointestinal tract.

1992 • 107 citations

Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver.

1993 • 77 citations

Transforming growth factor-alpha in human hepatocellular carcinoma and coexpression with hepatitis B surface antigen in adjacent liver

1992 • 74 citations

Proliferating cell nuclear antigen in oesophageal diseases; correlation with transforming growth factor alpha expression.

1992 • 70 citations

Expression of transforming growth factor alpha in human tissues: Immunohistochemical study and Northern blot analysis

1992 • 68 citations

Epidermal growth factor receptor as a target for therapy with antireceptor monoclonal antibodies.

1992 • 63 citations

Transforming Growth Factor-α and Epidermal Growth Factor Expression in Human Fetal Gastrointestinal Tract

1993 • 62 citations

Immunoreactive transforming growth factor alpha is commonly present in colorectal neoplasia.

1991 • 38 citations

Detection of transforming growth factor alpha in human urine and plasma

1990 • 36 citations

Serum levels of transforming growth factor-α in patients after partial hepatectomy as determined with an enzyme-linked immunosorbent assay

1993 • 36 citations

The Coupling between Transforming Growth Factor-α and the Epidermal Growth Factor Receptor during Rat Liver Regeneration

1993 • 35 citations

Expression of transforming growth factor alpha in human hepatocellular carcinoma

1993 • 29 citations

Transforming growth factor alpha in epithelial proliferative diseases of the breast.

1992 • 26 citations

[Immunohistochemical studies on epidermal growth factor receptor in hepatocellular carcinoma].

1991 • 13 citations

The effects of continuous exposure to epidermal growth factor on the spontaneous transformation of cultured rat liver epithelial cells.

1992 • 10 citations

A case of Echinostoma infection.

1999 • 6 citations

Immunohistochemical analysis of EGF receptor and myc product in human hepatoma cells.

1989 • 3 citations