Protein surface topology-probing by selective chemical modification and mass spectrometric peptide mapping.

Electrospray Ionization for Mass Spectrometry of Large Biomolecules

1989 • 7,324 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Crystallographic studies of the dynamic properties of lysozyme

1979 • 437 citations

Reversible modification of arginine residues. Application to sequence studies by restriction of tryptic hydrolysis to lysine residues

1975 • 385 citations

Small rearrangements in structures of Fv and Fab fragments of antibody D 1.3 on antigen binding

1990 • 247 citations

Demonstration by NMR of folding domains in lysozyme

1991 • 246 citations

Molecular epitope identification by limited proteolysis of an immobilized antigen-antibody complex and mass spectrometric peptide mapping.

1990 • 165 citations

Identification of functional arginine residues in ribonuclease A and lysozyme

1975 • 155 citations

Analysis of .vphi. and .chi.1 torsion angles for hen lysozyme in solution from proton NMR spin-spin coupling constants

1991 • 123 citations

Molecular dynamics simulations of native and substrate-bound lysozyme

1986 • 112 citations

Competitive labelling, a method for determining the reactivity of individual groups in proteins. The amino groups of porcine elastase

1971 • 111 citations

NMR identification of protein surfaces using paramagnetic probes

1990 • 91 citations

Epitope Mapping by Chemical Modification of Free and Antibody-Bound Protein Antigen

1987 • 87 citations

Recognition of trypsin autolysis products by high-performance liquid chromatography and mass spectrometry

1990 • 82 citations

Plasma desorption mass spectrometry: coming of age

1988 • 76 citations

A rapid, sensitive mass spectrometric method for investigating microscale chemical reactions of surface adsorbed peptides and proteins

1986 • 72 citations

Electrospray ionization mass spectrometric peptide mapping: A rapid, sensitive technique for protein structure analysis

1990 • 64 citations

An X-ray study of the physiological-temperature form of hen egg-white lysozyme at 2 Å resolution

1983 • 37 citations

Mass spectrometric determination of glycosylation sites and oligosaccharide composition of insect-expressed mouse interleukin-3

1991 • 23 citations

Fast atom bombardment mass spectrometric analysis of arginine-containing neuropeptides

1990 • 7 citations