Anticarcinogenic Effects of Retinoids in Animals

TISSUE CHANGES FOLLOWING DEPRIVATION OF FAT-SOLUBLE A VITAMIN

1925 • 1,630 citations

Diet and cancer

1979 • 555 citations

Dietary vitamin a and human lung cancer

1975 • 397 citations

N-(4-Hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat.

1979 • 388 citations

Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotion.

1979 • 361 citations

13- cis -Retinoic Acid: Inhibition of Bladder Carcinogenesis in the Rat

1977 • 256 citations

Vitamin A acid (retinoic acid), a potent inhibitor of 12-O-tetradecanoyl-phorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis.

1977 • 234 citations

DIETARY RISK FACTORS IN HUMAN BLADDER CANCER

1979 • 232 citations

Vitamin A and Lung Cancer<xref ref-type="fn" rid="FN2">2</xref>

1979 • 222 citations

An inhibitory effect of vitamin A on the induction of tumors of forestomach and cervix in the Syrian hamster by carcinogenic polycyclic hydrocarbons.

1965 • 218 citations

Growth factors produced by sarcoma virus-transformed cells.

1978 • 191 citations

Inhibition of carcinogenesis by retinoids.

1983 • 186 citations

Retinyl acetate inhibits mammary carcinogenesis induced by N-methyl-N-nitrosourea

1977 • 159 citations

Histogenesis of Squamous Metaplasia in the Hamster Tracheal Epithelium Caused by Vitamin A Deficiency or Benzo[&lt;italic&gt;a&lt;/italic&gt;]pyrene-Ferric Oxide

1972 • 156 citations

Reversible inhibition by retinoids of 3-methylcholanthrene-induced neoplastic transformation in C3H/10T1/2 clone 8 cells.

1979 • 154 citations

Inhibition of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis by retinyl acetate.

1976 • 149 citations

Rat Colon Carcinomas Associated with Aflatoxin and Marginal Vitamin A 2 3

1973 • 145 citations

Retinoids and Cancer

1984 • 143 citations

Induction by dimethylhydrazine of intestinal carcinoma in normal rats and rats fed high or low levels of vitamin A.

1973 • 136 citations

Retinoids block phenotypic cell transformation produced by sarcoma growth factor

1978 • 127 citations

A vitamin A analogue inhibits radiation-induced oncogenic transformation

1978 • 126 citations

13- cis -Retinoic Acid: Inhibition of Bladder Carcinogenesis Induced in Rats by N -Butyl- N -(4-hydroxybutyl)nitrosamine

1977 • 112 citations

α and β-Retinyl acetate reverse metaplasias of vitamin A deficiency in hamster trachea in organ culture

1974 • 111 citations

FROM VITAMIN A TO RETINOIDS IN EXPERIMENTAL AND CLINICAL ONCOLOGY: ACHIEVEMENTS, FAILURES, AND OUTLOOK

1981 • 110 citations

Inhibition of the effects of methylcholanthrene on mouse prostate in organ culture by vitamin A and its analogs.

1974 • 105 citations

Reversal of methylcholanthrene-induced changes in mouse prostates in vitro by retinoic acid and its analogues

1976 • 99 citations

Effect of retinoic acid, butylated hydroxytoluene, selenium and sorbic acid on azo-dye hepatocarcinogenesis

1980 • 96 citations

MULTISTAGE CARCINOGENESIS IN THE URINARY BLADDER

1980 • 95 citations

The influence of vitamin a on the susceptibility of the rat lung to 3‐methylcholanthrene

1976 • 95 citations

Preventive role of vitamin a in colon carcinogenesis in rats

1977 • 89 citations

Effect of avitaminosis A and hypervitaminosis A on urinary bladder carcinogenicity of N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamide.

1976 • 88 citations

12th International Congress of Chemotherapy

1980 • 79 citations

N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder cancer in C57BL/6 X DBA/2 F1 mice as a useful model for study of chemoprevention of cancer with retinoids.

1981 • 75 citations

Chemoprevention of mammary tumorigenesis by a combined regimen of selenium and vitamin A

1981 • 75 citations

Synergistic effect of chronic prolactin suppression and retinoid treatment in the prophylaxis of N-methyl-N-nitrosourea-induced mammary tumorigenesis in female Sprague-Dawley rats.

1980 • 69 citations

Inhibition of Benzo[&lt;italic&gt;a&lt;/italic&gt;]pyrene-Induced Mammary Carcinogenesis by Retinyl Acetate&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN3"&gt;3&lt;/xref&gt;

1981 • 67 citations

Inhibition and Reversal by β-Retinoic Acid of Hyperplasia Induced in Cultured Mouse Prostate Tissue by 3-Methylcholanthrene or N -Methyl- N′ -nitro- N -nitrosoguanidine 2

1976 • 64 citations

Effect of combined selenium and retinyl acetate treatment on mammary carcinogenesis.

1981 • 60 citations

N-(4-hydroxyphenyl)-all-trans-retinamide pharmacokinetics in female rats and mice.

1986 • 53 citations

Effect of Retinyl Acetate on the Incidence of Mammary Carcinomas and Hepatomas in Mice&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;

1980 • 46 citations

Vitamin A and benzo(a)pyrene carcinogenesis in the respiratory tract of hamsters fed a semisynthetic diet.

1975 • 45 citations

Inhibition of pancreatic carcinogenesis by retinoids in azaserine-treated rats.

1982 • 40 citations

Influence of delayed administration of retinyl acetate on mammary carcinogenesis.

1982 • 39 citations

Effect of retinoids on the induction of colon cancer in F344 rats by N-methyl-N-nitrosourea or by 1,2-dimethyihydrazine

1981 • 38 citations

Distribution of retinoic acid-binding proteins in normal and neoplastic mammary tissues.

1980 • 34 citations

Effect of three retinoids on tracheal carcinogenesis with N-methyl-N-nitrosourea in hamsters.

1981 • 33 citations

The influence of retinyl acetate on the postinitiation phase of preneoplastic lung nodules in rats.

1976 • 32 citations

Nuclear interactions of retinoic acid-binding protein in chemically induced mammary adenocarcinoma

1982 • 32 citations

Inhibition of mammary and urinary bladder carcinogenesis by a retinoid and a maleic anhydride-divinyl ether copolymer (MVE-2)

1982 • 30 citations

Diet and anticarcinogenesis in the mouse skin two-stage model.

1983 • 27 citations

Retinoids inhibit prolactin-induced development of the mammary gland in vitro

1983 • 26 citations

Inhibitory effect of an aromatic retinoic acid analog on urinary bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.

1980 • 25 citations

Retinoic acid binding proteins and steroid receptor levels in human breast cancer

1982 • 19 citations

Inhibition of DNA synthesis by retinyl acetate during chemically induced mammary carcinogenesis.

1980 • 19 citations

Sex differences in the effects of retinoids on carcinogenesis by N-nitrosobis(2-oxopropyl)amine in Syrian hamsters

1981 • 18 citations

Retinoid Binding in Normal and Neoplastic Mammary Tissue

1982 • 16 citations

Retinoids and Mammary Gland Differentiation

1985 • 16 citations

Experiments on the influence of an aromatic retinoid on the chemical carcinogenesis in rats by butyl-butanol-nitrosamine and 1,2-dimethylhydrazine.

1978 • 15 citations

Hormonal regulation of retinoic acid-binding proteins in the mammary gland

1981 • 12 citations

Inhibition by Retinoids of Neoplastic Transformation in vitro : Cellular and Biochemical Mechanisms

1985 • 11 citations

Histogenesis and Dose Dependence of &lt;italic&gt;N&lt;/italic&gt;-Methyl-&lt;italic&gt;N&lt;/italic&gt;-nitrosourea-Induced Carcinoma in a Localized Area of the Hamster Trachea&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN3"&gt;3&lt;/xref&gt;

1980 • 10 citations

Deleted Work

1955 • 0 citations