Fluorescence lifetime imaging: an application to the detection of skin tumors

New trends in photobiology

1992 • 1,194 citations

5‐Aminolevulinic Acid‐Based Photodynamic Therapy: Principles and Experimental Research

1997 • 630 citations

PHTHALOCYANINES AS PHOTODYNAMIC SENSITIZERS*

1991 • 539 citations

Photodynamic therapy of non-melanoma malignant tumours of the skin using topical δ-amino levulinic acid sensitization and laser irradiation

1994 • 432 citations

Ultraviolet laser‐induced fluorescence of colonic tissue: Basic biology and diagnostic potential

1992 • 430 citations

Autofluorescence of normal and malignant bronchial tissue

1991 • 383 citations

PRECLINICAL EXAMINATION OF FIRST and SECOND GENERATION PHOTOSENSITIZERS USED IN PHOTODYNAMIC THERAPY

1991 • 353 citations

Repetitive photodynamic therapy with topical δ-aminolaevulinic acid as an appropriate approach to the routine treatment of superficial non-melanoma skin tumours

1995 • 271 citations

Fluorescence photodetection of neoplastic urothelial lesions following intravesical instillation of 5-aminolevulinic acid

1994 • 270 citations

Porphyrins, porphyrias, cancer and photodynamic therapy — a model for carcinogenesis

1993 • 209 citations

Inhalation of 5-aminolevulinic acid: a new technique for fluorescence detection of early stage lung cancer

1996 • 161 citations

Fluorescence and Absorption Contrast Mechanisms for Biomedical Optical Imaging Using Frequency-Domain Techniques

1997 • 151 citations

Lipofuscin: Resolution of Discrepant Fluorescence Data

1982 • 149 citations

Development of a multivariate statistical algorithm to analyze human cervical tissue fluorescence spectra acquired in vivo

1996 • 142 citations

Natural fluorescence of normal and neoplastic human colon: A comprehensive “ex vivo” study

1995 • 122 citations

Rapid multiexcitation fluorescence spectroscopy system for in vivo tissue diagnosis

1996 • 117 citations

Rapid acquisition, analysis, and display of fluorescence lifetime-resolved images for real-time applications

1997 • 109 citations

Malignant tumor and atherosclerotic plaque diagnosis using laser-induced fluorescence

1990 • 85 citations

Laser excited fluorescence of hematoporphyrin derivative for diagnosis of cancer

1984 • 74 citations

Quantification of the hematoporphyrin derivative by fluorescence measurement using dual-wavelength excitation and dual-wavelength detection

1993 • 74 citations

Fluorescence Lifetime Imaging of Experimental Tumors in Hematoporphyrin Derivative‐Sensitized Mice

1997 • 73 citations

Laser-Induced Fluorescence Studies of Hematoporphyrin Derivative (HPD) in Normal and Tumor Tissue of Rat

1984 • 63 citations

TIME‐GATED FLUORESCENCE IMAGING FOR THE DIAGNOSIS OF TUMORS IN A MURINE MODEL

1993 • 62 citations

Kinetics and localisation of PpIX fluorescence after topical and systemic ALA application, observed in skin and skin tumours of UVB-treated mice

1996 • 62 citations

Fundamental Differences of Excitation Spectrum between Malignant and Benign Breast Tissues

1997 • 60 citations

Time-resolved in-vivo fluorescence of photosensitizing porphyrins

1993 • 57 citations

Clinical results of photodynamic therapy for superficial skin malignancies or actinic keratosis using topical 5-aminolaevulinic acid

1996 • 52 citations

Intrinsic Fluorescence of Proteins

1983 • 50 citations

Digital background subtraction for fluorescence imaging

1986 • 45 citations

Characterization of ultraviolet laser-induced autofluorescence of ceroid deposits and other structures in atherosclerotic plaques as a potential diagnostic for laser angiosurgery

1992 • 40 citations

Endoscopic tissue characterization by frequency-domain fluorescence lifetime imaging (FD-FLIM)

1997 • 37 citations

Tumor detection in mice by measurement of fluorescence decay time matrices

1995 • 27 citations

RATIOING FLUOROMETER PROBE FOR LOCALIZING CARCINOMA IN SITU IN BRONCHI OF THE LUNG

1987 • 25 citations

Characterization of the fluorescent morphological structures in human arterial wall using ultraviolet-excited microspectrofluorimetry

1991 • 25 citations

High contrast fluorescence imaging using two-wavelength laser excitation and image processing

1987 • 14 citations

Spectral variations of laser-induced tissue emission during in vivo detection of malignancies in the female genital tract

1997 • 9 citations

Whole-field fluorescence lifetime imaging with picosecond resolution for biomedicine

1998 • 3 citations

Whole-Field Fluorescence Lifetime Imaging with Picosecond Resolution for Biomedicine

2005 • 1 citations