Regulation of Hepatic Biliary Secretion

Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions

1969 • 589 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 519 citations

The Glucagon-sensitive Adenyl Cyclase System in Plasma Membranes of Rat Liver

1971 • 469 citations

Micelle formation by bile salts. Physical-chemical and thermodynamic considerations

1972 • 411 citations

Uptake of Taurocholic Acid into Isolated Rat‐Liver Cells

1975 • 275 citations

Secretion of organic anions in the formation of urine and bile.

1959 • 262 citations

Uptake of bile acids by perfused rat liver

1976 • 244 citations

Mechanism of phenobarbital-induced hypercholeresis in the rat

1970 • 209 citations

Canalicular bile production in dogs

1968 • 209 citations

Mechanisms and Control of Secretion of Bile Water and Electrolytes

1974 • 167 citations

Two Sites of Bile Formation as Determined by Mannitol and Erythritol Clearance in the Guinea Pig*

1967 • 165 citations

Mechanisms of Hepatic Bile Formation

1977 • 160 citations

The Enterohepatic Circulation of Bile Salts

1972 • 158 citations

THE RELATIONSHIP BETWEEN TAUROCHOLATE SECRETION RATE AND BILE PRODUCTION IN THE UNANESTHETIZED DOG DURING CHOLINERGIC BLOCKADE AND DURING SECRETIN ADMINISTRATION*

1962 • 157 citations

Canalicular Bile Secretion in Man STUDIES UTILIZING THE BILIARY CLEARANCE OF [14C]MANNITOL

1974 • 129 citations

Biliary lipid secretion and bile composition after acute and chronic interruption of the enterohepatic circulation in the rhesus monkey

1971 • 129 citations

Canalicular bile formation in the isolated perfused rat liver

1971 • 128 citations

Kinetics of Taurocholate Uptake by the Perfused Rat Liver

1975 • 127 citations

Role of bile ducts during secretin choleresis in dogs

1966 • 124 citations

Canalicular bile flow and bile secretory pressure. Evidence for a non-bile salt dependent fraction in the isolated perfused rat liver.

1970 • 113 citations

Relationship between the Biliary Excretion of Bile Acids and the Excretion of Water, Lecithin, and Cholesterol in Man

1971 • 106 citations

Properties of (Na+ + K+)-activated ATPase in rat liver plasma membranes enriched with bile canaliculi

1975 • 97 citations

Regulation of Pool Size of Bile Acids in Man

1977 • 95 citations

Biliary excretion of inulin, sucrose, and mannitol: analysis of bile formation

1961 • 90 citations

Acute taurine depletion and maximal rates of hepatic conjugation and secretion of cholic acid in the dog.

1965 • 84 citations

Relationship between bile flow and Na+, K+-adenosinetriphosphatase in liver plasma membranes enriched in bile canaliculi.

1977 • 79 citations

The Choleretic Effects of Glucagon and Secretin in the Dog

1971 • 77 citations

The enterohepatic circulation of bile acids in man.

1976 • 72 citations

Bile Acid-Induced Increase in Bile Acid-Independent Flow and Plasma Membrane NaK-ATPase Activity in Rat Liver

1978 • 70 citations

Canalicular Bile Production in Man*

1975 • 65 citations

Choleretic effects of cholecystokinin, gastrin II, and caerulein in the dog

1970 • 64 citations

The Effect of Secretin on Bile Formation in Man

1949 • 64 citations

Bile formation in guinea pigs: analysis with inert solutes of graded molecular radius

1968 • 64 citations

The Clearance of Mannitol and Erythritol In Rat Bile.

1967 • 63 citations

Hepatocellular uptake of inulin, sucrose, and mannitol in rats

1970 • 63 citations

Hydrocortisone choleresis in the dog

1970 • 52 citations

Bile Flow and Composition During Bile Acid Depletion and Administration

1974 • 48 citations

Effect of vagus nerve stimulation on hepatic secretion of bile in human subjects

1966 • 47 citations

ON THE EXISTENCE OF SECRETORY NERVES IN THE VAGI FOR AND THE REFLEX EXCITATION AND INHIBITION OF BILE SECRETION

1937 • 46 citations

Cyclic Amp in Secretin Choleresis

1976 • 45 citations

Choleretic effects of secretin and histamine in the dog

1969 • 44 citations

Ouabain-mediated sodium uptake and bile formation by isolated perfused rat liver

1976 • 38 citations

Effect of electrical vagal stimulation on canine hepatic bile flow

1974 • 35 citations

Secretion of Bile in Response to Food with and without Bile in the Intestine

1998 • 34 citations

Synthesis of a heptacosapeptide amide with the hormonal activity of sccretin.

1966 • 33 citations

Analysis of the components of bile flow in the rhesus monkey

1975 • 33 citations

Effect of theophylline of hepatic excretory function

1974 • 33 citations

Hepatocellular Uptake of Bile Acids in the Dog: Evidence for a Common Carrier-Mediated Transport System

1975 • 31 citations

Physiology of bile flow.

1972 • 30 citations

Effect on Bile Formation of Inhibitors of Sodium Transport

1969 • 30 citations

Effects of secretin and bile salt infusions on canine bile composition and flow

1972 • 29 citations

Influence of glucagon on canalicular bile production in the dog.

1974 • 28 citations

Electrolyte composition of the secretin fraction of bile from the perfused pig liver

1968 • 28 citations

THE METABOLISM OF BILE ACIDS

1919 • 27 citations

Possible explanations for the differences in secretory characteristics between conjugated and free bile acids.

1977 • 26 citations

Effect of Selective and Truncal Vagotomy on Insulin-Stimulated Bile Secretion in Dogs

1971 • 25 citations

Choleresis Induced by Stimulation of the Gastric Antrum

1967 • 25 citations

Synthesis and Enterohepatic Circulation of Bile Salts

1977 • 22 citations

Effect of insulin on canalicular bile formation

1976 • 21 citations

Effect of Bile Salt and Secretin upon Bile Flow from the Isolated Perfused Pig Liver

1967 • 21 citations

Bile Production in Fasted and Fed Primates

1974 • 21 citations

Comparison of the choleretic properties of bile acids

1973 • 20 citations

Effect of ethacrynic acid on bile formation in sheep, dogs, rats, guinea pigs and rabbits.

1972 • 20 citations

The choleretic mechanisms of sodium taurocholate, secretin, and glucagon.

1975 • 19 citations

Secretion by the common duct in response to secretin.

1971 • 19 citations

The secretory characteristics of dehydrocholate in the dog: comparison with the natural bile salts.

1976 • 15 citations

Comparison of Dose–Response Relations of Insulin and 2-Deoxy-D-Glucose for Biliary and Gastric Acid Secretion in Dogs

1970 • 15 citations

Hormonal regulation of bile secretion: a study in the isolated, perfused liver.

1969 • 15 citations

The Choleretic Response to Feeding in Dogs

1969 • 14 citations

Role of pyloric antrum in choleresis after insulin and feeding

1967 • 13 citations

The Effect of Vagotomy on Biliary Secretions and Bile Salt Pools in Dogs

1974 • 13 citations

The effect of insulin on bile-salt-independent canalicular secretion.

1978 • 13 citations

Effect of Truncal Vagotomy on 2-Deoxy-D-Glucose and Insulin Choleresis

1972 • 11 citations

Effect of truncal vagotomy on insulin choleresis.

1973 • 9 citations

Effect of pentagastrin on cholecystokinin and secretin choleresis in the dog

1974 • 8 citations

Effect of the histamine (H2) inhibitor metiamide on histamine-stimulated bile flow in dogs

1976 • 8 citations

The effect of atropine on bile secretion in dogs.

1971 • 8 citations

Effect of Pentagastrin on Canine Bile Flow

1973 • 8 citations

Role of the common bile duct in formation of bile and in gastrin-induced choleresis.

1971 • 8 citations

Effect of secretin on bile osmolality.

1969 • 6 citations

Effect of Cholinergic Blockade on Insulin Choleresis in Dogs

1974 • 6 citations

The effect of feeding on the bile salt-independent canalicular secretion in dogs

1978 • 6 citations

An analysis of the choleretic effect of insulin

1973 • 4 citations

Gastro‐Intestinal Hormones and Bile Secretion in the Perfused Pig Liver: The Effects of Secretin, Cholecystokinin and Pentagastrin

1974 • 3 citations

The choleretic effect of pure natural cholecystokinin in dogs.

1973 • 3 citations

The effect of insulin and atropine on bile volume and composition

1977 • 3 citations

The effect of truncal vagotomy on taurocholate choleresis and secretin choleresis

1977 • 3 citations

Assessing Changes in Canalicular Permeability

1972 • 3 citations