Clinical applications of proton MR spectroscopy

The Nuclear Induction Experiment

1946 • 1,164 citations

Localized high‐resolution proton NMR spectroscopy using stimulated echoes: Initial applications to human brain in vivo

1989 • 712 citations

Development of the human brain: In vivo quantification of metabolite and water content with proton magnetic resonance spectroscopy

1993 • 673 citations

A review of chemical issues in ¹H NMR spectroscopy: N‐acetyl‐l‐aspartate, creatine and choline

1991 • 656 citations

Absolute concentrations of metabolites in the adult human brain in vivo: quantification of localized proton MR spectra.

1993 • 565 citations

Noninvasive differentiation of tumors with use of localized H-1 MR spectroscopy in vivo: initial experience in patients with cerebral tumors.

1989 • 402 citations

Mapping of brain tumor metabolites with proton MR spectroscopic imaging: clinical relevance.

1992 • 357 citations

Alzheimer disease: depiction of increased cerebral myo-inositol with proton MR spectroscopy.

1993 • 354 citations

Metabolic disorders of the brain in chronic hepatic encephalopathy detected with H-1 MR spectroscopy.

1992 • 347 citations

Cerebral metabolism in man after acute stroke: New observations using localized proton NMR spectroscopy

1989 • 326 citations

Age-dependent changes in localized proton and phosphorus MR spectroscopy of the brain.

1990 • 307 citations

Proton MR Spectroscopy of Intracranial Tumours

1990 • 301 citations

Probable Alzheimer disease: diagnosis with proton MR spectroscopy.

1995 • 295 citations

Proton magnetic resonance spectroscopy of human brain in vivo in the evaluation of multiple sclerosis: Assessment of the load of disease

1990 • 289 citations

Human brain tumors: assessment with in vivo proton MR spectroscopy.

1993 • 287 citations

High-resolution 1H nuclear magnetic resonance study of cerebral hypoxia in vivo.

1983 • 283 citations

Human brain tumors: spectral patterns detected with localized H-1 MR spectroscopy.

1992 • 265 citations

Functional Brain Imaging

2013 • 264 citations

Metabolic imaging of patients with intracranial tumors: H-1 MR spectroscopic imaging and PET.

1990 • 262 citations

Mitochondrial disorders: analysis of their clinical and imaging characteristics.

1993 • 256 citations

Gray matter heterotopias: MR characteristics and correlation with developmental and neurologic manifestations.

1992 • 244 citations

Deep white matter infarction: correlation of MR imaging and histopathologic findings.

1988 • 239 citations

Subclinical hepatic encephalopathy: proton MR spectroscopic abnormalities.

1994 • 212 citations

Human brain infarction: proton MR spectroscopy.

1992 • 180 citations

Acute stroke: evaluation with serial proton MR spectroscopic imaging.

1994 • 171 citations

Metabolic and destructive brain disorders in children: findings with localized proton MR spectroscopy.

1991 • 171 citations

Temporal lobe epilepsy: presurgical localization with proton chemical shift imaging.

1994 • 163 citations

AIDS dementia complex: evaluation with proton MR spectroscopic imaging.

1995 • 147 citations

Localized 1H NMR Spectroscopy in Fifty Cases of Newly Diagnosed Intracranial Tumors

1991 • 139 citations

Magnetic Resonance in Epilepsy.

1997 • 136 citations

Proton magnetic resonance spectroscopy of human brain: Applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities

1992 • 134 citations

Solvent-suppressed spatially resolved spectroscopy. An approach to high-resolution NMR on a whole-body MR system

1986 • 126 citations

MELAS syndrome: imaging and proton MR spectroscopic findings.

1995 • 125 citations

Proton MR spectroscopy of HIV-infected patients: characterization of abnormalities with imaging and clinical correlation.

1993 • 119 citations

¹H and ³¹P magnetic resonance spectroscopy of the brain in degenerative cerebral disorders

1992 • 113 citations

Proton MR spectroscopy of the brain in 14 patients with Parkinson disease.

1995 • 108 citations

¹H NMR detection of cerebral myo‐inositol

1985 • 105 citations

Proton magnetic resonance and human thyroid neoplasia I: Discrimination between benign and malignant neoplasms

1994 • 89 citations

Central nervous system trans‐synaptic effects of acute axonal injury: a ¹h magnetic resonance spectroscopy study

1995 • 86 citations

Childhood adrenoleukodystrophy: assessment with proton MR spectroscopy.

1993 • 80 citations

Use of computed tomography, magnetic resonance imaging, and localized 1H magnetic resonance spectroscopy in canavan's disease: A case Report

1991 • 71 citations

Analysis of cerebral structural changes in systemic lupus erythematosus by proton MR spectroscopy.

1994 • 59 citations

Measurement of human brain lithium in vivo by MR spectroscopy.

1993 • 40 citations

Correlation between choline level and Gd‐DTPA enhancement in patients with brain metastases of mammary carcinoma

1994 • 40 citations

Proton MR spectroscopy of brain abnormalities in neonates born to HIV-positive mothers.

1994 • 26 citations

PROTON SPECTROSCOPY OF THE BRAIN IN HIV-INFECTION - CORRELATION WITH CLINICAL, IMMUNOLOGICAL, AND MR-IMAGING FINDINGS

1993 • 26 citations

Ocular MR imaging and spectroscopy: an ex vivo study.

1986 • 25 citations

The use of magnetic resonance imaging and spectroscopy in the assessment of patients with head and neck and other superficial human malignancies

1989 • 25 citations

Potential Use of In Vivo Proton Spectroscopy for Head and Neck Lesions

1989 • 15 citations

Proton MR spectroscopy in a possible enhancing hamartoma in a patient with neurofibromatosis type 1

1995 • 15 citations

Proton MR Spectroscopic Characteristics of a Presumed Giant Subcortical Heterotopia

1993 • 14 citations

Measurement of psychoactive drugs in the human brain in vivo by MR spectroscopy

1993 • 12 citations

In Vitro NMR Evaluation of Human Thyroid Lesions

1989 • 9 citations