Effect of dystrophin gene deletions on mRNA levels and processing in Duchenne and Becker muscular dystrophies

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Dystrophin: The protein product of the duchenne muscular dystrophy locus

1987 • 4,477 citations

The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein

1988 • 1,501 citations

The Molecular Basis of Muscular Dystrophy in the mdx Mouse: a Point Mutation

1989 • 1,171 citations

An explanation for the phenotypic differences between patients bearing partial deletions of the DMD locus

1988 • 1,140 citations

The molecular basis for Duchenne versus Becker muscular dystrophy: correlation of severity with type of deletion.

1989 • 940 citations

Characterization of Dystrophin in Muscle-Biopsy Specimens from Patients with Duchenne's or Becker's Muscular Dystrophy

1988 • 910 citations

Transcription of the dystrophin gene in human muscle and non-muscle tissues

1988 • 733 citations

Illegitimate transcription: transcription of any gene in any cell type.

1989 • 647 citations

Very mild muscular dystrophy associated with the deletion of 46% of dystrophin

1990 • 578 citations

Topography of the Duchenne muscular dystrophy (DMD) gene: FIGE and cDNA analysis of 194 cases reveals 115 deletions and 13 duplications.

1989 • 498 citations

Detailed analysis of the repeat domain of dystrophin reveals four potential hinge segments that may confer flexibility.

1990 • 384 citations

Alternative splicing of human dystrophin mRNA generates isoforms at the carboxy terminus

1989 • 332 citations

Dystrophin abnormalities in Duchenne/Becker muscular dystrophy

1989 • 330 citations

Frame-Shift Deletions in Patients with Duchenne and Becker Muscular Dystrophy

1988 • 276 citations

Nonsense mutations in the human beta-globin gene affect mRNA metabolism.

1988 • 229 citations

Quantitative estimation of minor mRNAs by cDNA‐polymerase chain reaction

1990 • 196 citations

Expression of the Murine Duchenne Muscular Dystrophy Gene in Muscle and Brain

1988 • 190 citations

Familial X-linked myalgia and cramps: A nonprogressive myopathy associated with a deletion in the dystrophin gene

1989 • 141 citations

GENETICS OF DUCHENNE MUSCULAR DYSTROPHY

1988 • 124 citations

Beta O-39 thalassemia gene: a premature termination codon causes beta- mRNA deficiency without affecting cytoplasmic beta-mRNA stability

1984 • 106 citations

Intranuclear defect in beta-globin mRNA accumulation due to a premature translation termination codon

1984 • 102 citations

Beta O-39 thalassemia gene: a premature termination codon causes beta- mRNA deficiency without affecting cytoplasmic beta-mRNA stability

1984 • 82 citations

Gene deletions in X-linked muscular dystrophy.

1989 • 73 citations

Cloning of the Duchenne/Becker Muscular Dystrophy Locus

1988 • 68 citations

Duchenne Muscular Dystrophy Gene Expression in Normal and Diseased Human Muscle

1988 • 59 citations

Analysis of molecular deletions with cDNA probes in patients with Duchenne and Becker muscular dystrophies

1989 • 31 citations

Transcription of the dystrophin gene in Duchenne muscular dystrophy muscle

1989 • 18 citations