BRAF mutations in an Italian cohort of thyroid cancers

Mutations of the BRAF gene in human cancer

2002 • 10,249 citations

Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF

2004 • 2,674 citations

High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma.

2003 • 1,490 citations

AJCC Cancer Staging Handbook

2010 • 1,383 citations

BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas

2003 • 1,042 citations

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

1999 • 970 citations

BRAF Mutation in Papillary Thyroid Carcinoma

2003 • 915 citations

BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC

2003 • 671 citations

Clinical Implication of Hot SpotBRAFMutation, V599E, in Papillary Thyroid Cancers

2003 • 539 citations

High prevalence of BRAF gene mutation in papillary thyroid carcinomas and thyroid tumor cell lines.

2003 • 424 citations

Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia.

2002 • 408 citations

Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.

1992 • 391 citations

BRAF mutations are associated with some histological types of papillary thyroid carcinoma

2004 • 366 citations

Development of anticancer drugs targeting the MAP kinase pathway

2000 • 322 citations

BRAF mutations in papillary carcinomas of the thyroid

2003 • 301 citations

Missense mutations of the BRAF gene in human lung adenocarcinoma.

2002 • 283 citations

In ovarian neoplasms, BRAF, but not KRAS, mutations are restricted to low‐grade serous tumours

2004 • 233 citations

RET/NTRK1 rearrangements in thyroid gland tumors of the papillary carcinoma family: correlation with clinicopathological features.

1998 • 175 citations

BRAF and KRAS mutations in stomach cancer

2003 • 139 citations

BRAF T1796A Transversion Mutation in Various Thyroid Neoplasms

2004 • 131 citations

BRAF Gene Is Somatically Mutated but Does Not Make a Major Contribution to Malignant Melanoma Susceptibility: The Italian Melanoma Intergroup Study

2004 • 56 citations