Characterization of immunotoxins active against ovarian cancer cell lines.

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Internalization and processing of transferrin and the transferrin receptor in human carcinoma A431 cells.

1983 • 636 citations

NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin,.

1975 • 619 citations

Characterization of a human ovarian carcinoma cell line (NIH:OVCAR-3) with androgen and estrogen receptors.

1983 • 534 citations

Transferrin receptors in human tissues: their distribution and possible clinical relevance.

1983 • 527 citations

Toxic lectins and related proteins

1982 • 305 citations

Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells

1980 • 305 citations

Immunotoxins: A New Approach to Cancer Therapy

1983 • 282 citations

Antibody-directed cytotoxic agents: use of monoclonal antibody to direct the action of toxin A chains to colorectal carcinoma cells.

1980 • 270 citations

Kinetics of protein synthesis inactivation by ricin-anti-Thy 1.1 monoclonal antibody hybrids. Role of the ricin B subunit demonstrated by reconstitution.

1982 • 200 citations

Kinetics of cytotoxicity induced by immunotoxins. Enhancement by lysosomotropic amines and carboxylic ionophores.

1984 • 194 citations

Experimental model systems of ovarian cancer: applications to the design and evaluation of new treatment approaches.

1984 • 162 citations

Characterization of a xenograft model of human ovarian carcinoma which produces ascites and intraabdominal carcinomatosis in mice.

1984 • 155 citations

The role of lymphatic obstruction in the formation of ascites in a murine ovarian carcinoma.

1972 • 136 citations

Inhibition of Human Acute Lymphoblastic Leukemia Cells by Immunotoxins: Potentiation by Chloroquine

1984 • 124 citations

Evaluation of monoclonal antibodies for the development of breast cancer immunotoxins.

1985 • 114 citations

Blockade of the galactose‐binding sites of ricin by its linkage to antibody

1984 • 93 citations

Pseudomonas exotoxin-anti-TAC. Cell-specific immunotoxin active against cells expressing the human T cell growth factor receptor.

1984 • 92 citations

Anti-transferrin receptor antibody linked to Pseudomonas exotoxin as a model immunotoxin in human ovarian carcinoma cell lines.

1985 • 91 citations

Tissue distribution of breast cancer-associated antigens defined by monoclonal antibodies.

1985 • 88 citations

Enhancement of toxicity of antitransferrin receptor antibody-Pseudomonas exotoxin conjugates by adenovirus.

1983 • 72 citations

Chemotherapy by intravenous administration of conjugates of daunomycin with monoclonal and conventional anti-rat alpha-fetoprotein antibodies.

1982 • 66 citations

Cytotoxicity of a cell-reactive immunotoxin containing ricin A chain is potentiated by an anti-immunotoxin containing ricin B chain.

1984 • 66 citations

Potentiation of cytotoxic activity of immunotoxins on cultured human cells.

1985 • 46 citations