Pathogenesis of secondary hyperparathyroidism

Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid

1993 • 2,625 citations

A novel cyclin encoded by a bcl1-linked candidate oncogene

1991 • 1,286 citations

Mutations in the human Ca2+-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism

1993 • 1,038 citations

Decreased 1,25-dihydroxyvitamin D3 receptor density is associated with a more severe form of parathyroid hyperplasia in chronic uremic patients.

1993 • 594 citations

Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro.

1996 • 512 citations

Depressed expression of calcium receptor in parathyroid gland tissue of patients with hyperparathyroidism

1997 • 494 citations

Reduced immunostaining for the extracellular Ca2+-sensing receptor in primary and uremic secondary hyperparathyroidism.

1996 • 487 citations

Effect of Phosphate, Calcium and Magnesium on Bone Resorption and Hormonal Responses in Tissue Culture

1969 • 410 citations

Parathyroid cell proliferation in normal and chronic renal failure rats. The effects of calcium, phosphate, and vitamin D.

1995 • 407 citations

Molecular cloning and chromosomal mapping of DNA rearranged with the parathyroid hormone gene in a parathyroid adenoma.

1989 • 367 citations

Direct effect of phosphorus on PTH secretion from whole rat parathyroid glands in vitro

1996 • 326 citations

RNA-Protein Binding and Post-transcriptional Regulation of Parathyroid Hormone Gene Expression by Calcium and Phosphate

1998 • 302 citations

The role of phosphate in the secretion of parathyroid hormone in man

1970 • 290 citations

Reduced Binding of [³H]l,25-Dihydroxyvitamin D₃in the Parathyroid Glands of Patients with Renal Failure

1987 • 273 citations

On the prevention of secondary hyperparathyroidism in experimental chronic renal disease using “proportional reduction” of dietary phosphorus intake

1972 • 271 citations

1,25(OH)2 vitamin D3 inhibits parathyroid cell proliferation in experimental uremia

1989 • 269 citations

Abnormal Regulation of Parathyroid Hormone Release by Calcium in Secondary Hyperparathyroidism due to Chronic Renal Failure*

1982 • 256 citations

Up-regulation of the vitamin D receptor in response to 1,25-dihydroxyvitamin D3 results from ligand-induced stabilization.

1992 • 224 citations

Rat calcium-sensing receptor is regulated by vitamin D but not by calcium

1996 • 224 citations

Parathyroid hormone gene expression in hypophosphatemic rats.

1995 • 203 citations

Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors.

1991 • 203 citations

Hyperparathyroidism and renal failure

1973 • 173 citations

1,25-(OH)2D receptors are decreased in parathyroid glands from chronically uremic dogs

1989 • 149 citations

Inhibition of calcitriol receptor binding to vitamin D response elements by uremic toxins.

1995 • 141 citations

A direct effect in vitro of phosphate on PTH release from bovine parathyroid tissue slices but not from dispersed parathyroid cells

1996 • 135 citations

Parathyroid hormone secretion in vivo. Demonstration of a calcium-independent nonsuppressible component of secretion.

1976 • 134 citations

Diminished parathyroid 1,25(OH)2D3 receptors in experimental uremia

1987 • 123 citations

Molecular Cloning and Hormonal Regulation of PiT-1, a Sodium-Dependent Phosphate Cotransporter from Rat Parathyroid Glands¹

1998 • 108 citations

A direct effect in vitro of phosphate on PTH release from bovine parathyroid tissue slices but not from dispersed parathyroid cells

1996 • 100 citations

1,25-Dihydroxyvitamin D3 and 22-oxacalcitriol prevent the decrease in vitamin D receptor content in the parathyroid glands of uremic rats

1996 • 96 citations

Prevention of Enhanced Parathyroid Hormone Secretion, Synthesis and Hyperplasia by Mild Dietary Phosphorus Restriction in Early Chronic Renal Failure in Rats: Possible Direct Role of Phosphorus

1995 • 85 citations

Parathyroid cell proliferation in the rat: effect of age and of phosphate administration and recovery.

1996 • 71 citations

Experimental Model for Hyperparathyroidism: Effect of Excessive Numbers of Transplanted Isologous Parathyroid Glands

1966 • 69 citations

Negative regulatory elements in the human parathyroid hormone gene.

1991 • 60 citations

Altered Adenylate Cyclase Kinetics in Hyperfunctioning Human Parathyroid Glands*

1981 • 43 citations

Inhibition of nuclear uptake of calcitriol receptor by uremic ultrafiltrate

1994 • 33 citations