The role of organic osmolytes in osmoregulation: From bacteria to mammals

Living with Water Stress: Evolution of Osmolyte Systems

1982 • 3,735 citations

The Mechanism of Salt Tolerance in Halophytes

1977 • 1,957 citations

Microbial water stress

1976 • 742 citations

Renal medullary organic osmolytes

1991 • 516 citations

Role of amino acids in osmoregulation of non-halophilic bacteria

1975 • 509 citations

Water Relations of Sugar-tolerant Yeasts: the Role of Intracellular Polyols

1972 • 399 citations

Predominant osmotically active organic solutes in rat and rabbit renal medullas.

1986 • 382 citations

The salt relations of marine and halophilic species of the unicellular green alga,Dunaliella

1974 • 355 citations

Untersuchungen zum Problem der Harnkonzentrierung und Harnverd�nnung

1956 • 246 citations

Survival of Frogs in Low Temperature

1982 • 201 citations

The Control of Emergence and Metabolism by External Osmotic Pressure and the Role of Free Glycerol in Developing Cysts of Artemia Salina

1964 • 182 citations

Betaine and choline levels in plants and their relationship to NaCl stress

1975 • 174 citations

Induction of aldose reductase and sorbitol in renal inner medullary cells by elevated extracellular NaCl.

1987 • 173 citations

Adaptation of nitrogen metabolism to hyperosmotic environment in Amphibia

1981 • 141 citations

Carbon-13 Nuclear Magnetic Resonance Study of Osmoregulation in a Blue-Green Alga

1980 • 138 citations

Intracellular osmoregulatory role of amino acids and urea in marine elasmobranchs

1976 • 136 citations

Osmoregulatory changes in myo-inositol transport by renal cells.

1989 • 132 citations

ROLE OF GLYCEROL IN THE COLD-HARDENING OF BRACON CEPHI (GAHAN)

1959 • 127 citations

Purification of rat papillary collecting duct cells: functional and metabolic assessment

1987 • 124 citations

The free amino-acid pool in Callinectes sapidus (Rathbun) tissues and its role in the osmotic intracellular regulation

1972 • 123 citations

Survey of osmolytes in renal cell lines

1988 • 119 citations

Intra- and extracellular element concentrations of rat renal papilla in antidiuresis

1984 • 113 citations

Target Cell Polarity and Membrane Phosphorylation in Relation to the Mechanism of Action of Antidiuretic Hormone

1974 • 107 citations

[Studies on the problem of urine concentration and dilution; distribution of electrolytes (sodium, potassium, calcium, magnesium, anorganic phosphate), urea amino acids and exogenous creatinine in the cortex and medulla of dog kidney in various diuretic conditions].

1956 • 106 citations

Osmoregulation of betaine transport in mammalian renal medullary cells

1990 • 104 citations

Free amino acids in tissues of the skate Raja erinacea and the stingray Dasyatis sabina: Effects of environmental dilution

1977 • 103 citations

Osmoregulation by slow changes in aldose reductase and rapid changes in sorbitol flux

1988 • 98 citations

Halotolerance of Dunaliella

1979 • 97 citations

Natural Occurrence of Glycerol in Insects and Its Relation to Their Ability to Survive Freezing

1957 • 97 citations

RETRACTED: Accumulation of glycerophosphocholine (GPC) by renal cells: osmotic regulation of GPC:choline phosphodiesterase.

1991 • 95 citations

Nitrogen-14 nuclear magnetic resonance spectroscopy of mammalian tissues

1983 • 86 citations

Der einfluß von NaCl auf die Prolinkonzentration verschiedener Halophyten

1975 • 84 citations

OSMOTIC CONSTITUENTS OF THE BLOOD PLASMA AND PARIETAL MUSCLE OF SQUALUS ACANTHIAS L

1975 • 82 citations

Myo-inositol and betaine transporters regulated by tonicity are basolateral in MDCK cells

1991 • 79 citations

Vasopressin stimulates endocytosis in kidney collecting duct principal cells.

1988 • 71 citations

Holeuryhalinity and its mechanisms in a cirriped crustacean, Balanus improvisus

1976 • 70 citations

Studies on the Chemical Composition of Muscle Tissue

1965 • 70 citations

OSMOREGULATION IN A MARINE CILIATE,MIAMIENSIS AVIDUS.II. REGULATION OF INTRACELLUAR FREE AMINO ACIDS

1969 • 69 citations

Osmotically active organic solutes in the renal inner medulla

1987 • 68 citations

Regulation of organic osmolyte concentrations in tubules from rat renal inner medulla

1989 • 67 citations

Na‐K‐Cl Cotransport in Chloride‐transporting Epithelia^a

1985 • 65 citations

Steps in p-aminohippurate transport by kidney slices

1958 • 62 citations

Chemical composition of the body fluids andmuscle of the hagfish Myxine glutinosa and the rabbit‐fish Chimaera monstrosa

1976 • 60 citations

Role of Changes in Solute Concentration in Maintaining Favorable Water Balance in Field‐Grown Cotton¹

1977 • 59 citations

Development of sodium regulation and de novo synthesis of Na+K‐activated ATPase in larval brine shrimp, Artemia salina

1977 • 59 citations

The time course of changes in renal tissue composition during water diuresis in the rat

1968 • 58 citations

Osmoregulation of renal papillary cells

1985 • 56 citations

High NaCl induces stable changes in phenotype and karyotype of renal cells in culture

1987 • 55 citations

From Dogfish to Dogs: Trimethylamines Protect Proteins from Urea

1986 • 52 citations

Intracellular sorbitol content in isolated rat inner medullary collecting duct cells

1989 • 52 citations

Adenosine receptor-mediated calcium mobilization in cortical collecting tubule cells

1988 • 52 citations

�ber das Vorkommen von Phosphorverbindungen in verschiedenen Nierenabschnitten und �nderungen ihrer Konzentration in Abh�ngigkeit vom Diuresezustand

1956 • 50 citations

A SURVEY OF THE EFFECT OF OSMOTIC DILUTION ON FREE AMINO ACIDS OF VARIOUS POLYCHAETES

1968 • 47 citations

A novel sorbitol transport mechanism in cultured renal papillary epithelial cells

1989 • 46 citations

Regulation of the Predominant Renal Medullary Organic Solutes In Vivo

1990 • 45 citations

Osmotically regulated taurine content in rat renal inner medulla

1991 • 43 citations

Activation of osmolyte efflux from cultured renal papillary epithelial cells

1991 • 41 citations

Comparative Aspects of Cell Osmoregulation and Volume Control

1988 • 40 citations

Some effects of inorganic ions on the active transport of phenol red by isolated kidney tubules of the flounder

1952 • 39 citations

Effect of partial Na pump and Na-H exchange inhibition on [Ca]i during acidosis in cardiac cells

1991 • 39 citations

Localization of phosphorus metabolites and sodium ions in the rat kidney

1986 • 35 citations

p-Aminohippuric acid transport into brush border vesicles isolated from flounder kidney

1979 • 34 citations

Osmotic constituents of some echinoderm muscles

1980 • 32 citations

Role of Ca2+ in sorbitol release from rat inner medullary collecting duct (IMCD) cells under hypoosmotic stress

1990 • 32 citations

Renal transport mechanisms.

1967 • 31 citations

NMR studies of renal phosphate metabolites in vivo: effects of hydration and dehydration

1988 • 28 citations

Effects of low water potentials on some aspects of carbohydrate metabolism in Chlorella pyrenoidosa

1967 • 26 citations

Cellular Osmoregulation in Renal Medulla

1988 • 26 citations

Osmotic Regulation

1979 • 24 citations

Studies on Water in Barnacle Muscle Fibres I. The Dry Weight Components of Fresh Fibres

1981 • 19 citations

Determination of intact-tissue glycerophosphorylcholine levels by quantitative 31P nuclear magnetic resonance spectroscopy and correlation with spectrophotometric quantification

1985 • 17 citations

Renal excretion of chlorphenol red and related organic acids in the intact flounder Pseudopleuronectes americanus

1977 • 16 citations

Untersuchungen zur Ökologie and Physiologie der marinen Blaualgenflechte Lichina pygmaea AG. III. Einige Aspekte der photosynthetischen C-Fixierung unter osmoregulatorischen Bedingungen

1975 • 16 citations

Phosphorus Metabolites by NMR

1984 • 15 citations

The Quantity and Chemical Composition of Ascophyllum nodosum (L) Le Jol. along the Coast between the Rivers Ölfusá and Thjorsá (Southern Iceland)

1964 • 15 citations

Biochemie der osmotischen Regulation bei Poterioochromonas malhamensis

1979 • 13 citations

Cellular osmoregulation in the renal papilla

1988 • 9 citations

Nefrología pediátrica

2009 • 9 citations

Frost-resistance in the diapausing pupa of the cecropia silkworm: A preliminary experiment

1967 • 2 citations