Age- and gender-related changes in the distribution of osteocalcin in the extracellular matrix of normal male and female bone. Possible involvement of osteocalcin in bone remodeling.

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Negative regulation of transforming growth factor-β by the proteoglycan decorin

1990 • 1,490 citations

Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis.

1981 • 1,193 citations

Osteonectin, a bone-specific protein linking mineral to collagen

1981 • 1,131 citations

Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence.

1986 • 1,078 citations

Relationship of cell growth to the regulation of tissue‐specific gene expression during osteoblast differentiation

1990 • 934 citations

Osteopontin--a possible anchor of osteoclasts to bone.

1990 • 816 citations

Characterization of a gamma-carboxyglutamic acid-containing protein from bone.

1976 • 782 citations

Direct identification of the calcium-binding amino acid, gamma-carboxyglutamate, in mineralized tissue.

1975 • 741 citations

Deduced protein sequence of bone small proteoglycan I (biglycan) shows homology with proteoglycan II (decorin) and several nonconnective tissue proteins in a variety of species

1989 • 706 citations

Human bone cellsin vitro

1985 • 696 citations

Expression and localization of the two small proteoglycans biglycan and decorin in developing human skeletal and non-skeletal tissues.

1990 • 657 citations

On Aging Bone Loss

1982 • 545 citations

Purification and partial characterization of small proteoglycans I and II, bone sialoproteins I and II, and osteonectin from the mineral compartment of developing human bone.

1987 • 437 citations

Different pattern of alkaline phosphatase, osteopontin, and osteocalcin expression in developing rat bone visualized by in situ hybridization

1990 • 436 citations

Mineral and collagen-binding proteins of fetal calf bone.

1981 • 379 citations

Structure of the rat osteocalcin gene and regulation of vitamin D-dependent expression.

1989 • 372 citations

Impaired vitamin D metabolism with aging in women. Possible role in pathogenesis of senile osteoporosis.

1984 • 360 citations

Nutritional status in a healthy elderly population: vitamin C

1982 • 342 citations

The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer.

1990 • 313 citations

A method for decarboxylation of gamma-carboxyglutamic acid in proteins. Properties of the decarboxylated gamma-carboxyglutamic acid protein from calf bone.

1979 • 277 citations

Recruitment of osteoclast precursors by purified bone matrix constituents.

1982 • 266 citations

Osteocalcin‐hydroxyapatite interaction in the extracellular organic matrix of bone

1989 • 220 citations

Nutritional status in a healthy elderly population: vitamin D

1982 • 217 citations

Rat osteoclasts adhere to a wide range of rgd (arg-gly-asp) peptide-containing proteins, including the bone sialoproteins and fibronectin, via a β3 integrin

1992 • 215 citations

Noncollagenous Proteins Influencing the Local Mechanisms of Calcification

1985 • 201 citations

Ultrastructural immunolocalization of noncollagenous (osteopontin and osteocalcin) and plasma (albumin and α2HS-glycoprotein) proteins in rat bone

1993 • 193 citations

Advancing Age Results in Reduction of Intestinal and Bone 1,25-Dihydroxyvitamin D Receptor

1990 • 180 citations

Alterations in Calcium, Vitamin D, and Parathyroid Hormone Physiology in Normal Men with Aging: Relationship to the Development of Senile Osteopenia*

1986 • 170 citations

Distribution of noncollagenous proteins in the matrix of adult human bone: Evidence of anatomic and functional heterogeneity

1993 • 167 citations

High‐resolution immunolocalization of osteopontin and osteocalcin in bone and cartilage during endochondral ossification in the chicken tibia

1992 • 166 citations

Serum Vitamin D₂and Vitamin D₃Metabolite Concentrations and Absorption of Vitamin D₂in Elderly Subjects*

1986 • 159 citations

Age changes in bone mineralization, cortical thickness, and Haversian canal area

1980 • 158 citations

Impaired recruitment and differentiation of osteoclast progenitors by osteocalcin-deplete bone implants

1987 • 153 citations

Resorption of implanted bone prepared from normal and warfarin-treated rats.

1984 • 153 citations

Perspectives: Adhesion receptors in bone

1989 • 136 citations

Age-related Changes in Parathyroid Hormone and 25 Hydroxycholecalciferol Levels

1983 • 131 citations

Transcriptional regulation of osteopontin production in rat osteoblast-like cells by parathyroid hormone.

1989 • 130 citations

Influence of vitamin D on parathyroid function in the elderly.

1992 • 123 citations

Transcriptional Regulation of Osteocalcin Production by Transforming Growth Factor-β in Rat Osteoblast-Like Cells

1989 • 114 citations

Human bone cells in vitro.

1985 • 111 citations

Heterogeneity of human bone

1990 • 106 citations

Vitamin D deficiency causes a selective reduction in deposition of transforming growth factor beta in rat bone: possible mechanism for impaired osteoinduction.

1991 • 105 citations

Ultrastructural Immunolocalization of Osteopontin in Metaphyseal and Cortical Bone

1991 • 89 citations

Morphology and biochemistry of bone remodeling: possible control by vitamin D, parathyroid hormone, and other substances.

1988 • 71 citations

Osteopetrosis in the Rat: Coexistence of Reductions in Osteocalcin and Bone Resorption*

1990 • 61 citations

Normal bone particles are preferentially resorbed in the presence of osteocalcin-deficient bone particlesIn vivo

1991 • 55 citations

Influence of vitamin D on parathyroid function in the elderly

1992 • 52 citations

Production and Metabolic Clearance of 1,25-Dihydroxyvitamin D in Men: Effect of Advancing Age*

1990 • 50 citations

Immunolocalization of noncollagenous bone matrix proteins in lumbar vertebrae from intact and surgically menopausal cynomolgus monkeys

1993 • 50 citations

Effect of declining renal function on bone density in aging women

1988 • 45 citations

Changes in Vitamin D Metabolism during Natural and Medical Menopause

1990 • 44 citations

Mineralization Ability of Cultured Human Osteoblast-like Periosteal Cells Does Not Decline With Aging

1991 • 41 citations

Age‐related changes in bone density, serum parathyroid hormone, calcium absorption and other indices of bone metabolism in Chinese women

1992 • 40 citations

Cellular activity, matrix proteins, and aging bone

1990 • 40 citations

Changes with Age in the Non-Collagenous Proteins of Human Bone

1985 • 38 citations

Matrix in Cartilage and Bone Development: Current Views on the Function and Regulation of Major Organic Components

1991 • 38 citations

Matrix protein profiles in calf bone development

1985 • 36 citations

Zonal Osteons in Cortical Bone

1974 • 30 citations

Osteoclast recruitment in response to human bone matrix is age related

1992 • 30 citations

Monoclonal antibodies against osteonectin show conservation of epitopes across species

1989 • 25 citations

The relationship of monocytic cells to the differentiation and resorption of bone.

1982 • 15 citations

TGF-beta and extracellular matrix related influences on gene expression and phenotype.

1991 • 10 citations

Sex and age distribution of 1,25(OH)2D3 receptors in peripheral blood mononuclear cells from normal human subjects

1990 • 4 citations