Evidence that stress and surgical interventions promote tumor development by suppressing natural killer cell activity

Natural Killer Cells: Their Roles in Defenses Against Disease

1981 • 1,353 citations

HEALTH PSYCHOLOGY: Psychological Factors and Physical Disease from the Perspective of Human Psychoneuroimmunology

1996 • 727 citations

Effects of stress on immune cell distribution. Dynamics and hormonal mechanisms.

1995 • 719 citations

Catecholamine-Induced Leukocytosis: Early Observations, Current Research, and Future Directions

1996 • 508 citations

Stress and Immune Responses After Surgical Treatment for Regional Breast Cancer

1998 • 395 citations

Stress-related immune suppression: Health implications

1987 • 389 citations

Stress and cancer.

1981 • 367 citations

Monoclonal antibody to a triggering structure expressed on rat natural killer cells and adherent lymphokine-activated killer cells.

1989 • 365 citations

Role of NK cells in the control of metastatic spread and growth of tumor cells in mice

1982 • 357 citations

Natural killer cells and cancer

1996 • 317 citations

Perturbing the organism: the biology of stressful experience

1993 • 283 citations

Stress and cancer.

1981 • 282 citations

Direct evidence for the role of LGL in the inhibition of experimental tumor metastases.

1985 • 279 citations

Role of organ-associated NK cells in decreased formation of experimental metastases in lung and liver.

1985 • 275 citations

In vivo beta-adrenergic stimulation suppresses natural killer activity and compromises resistance to tumor metastasis in rats.

1998 • 253 citations

MORTALITY AFTER BEREAVEMENT

1981 • 251 citations

Psychological Stress, Neuroimmunomodulation, and Susceptibility to Infectious Diseases in Animals and Man: A Review

1997 • 250 citations

Catecholamines modulate human NK cell circulation and function via spleen-independent beta 2-adrenergic mechanisms.

1996 • 248 citations

Stress increases metastatic spread of a mammary tumor in rats: Evidence for mediation by the immune system

1991 • 244 citations

Prognostic risk assessment in primary breast cancer by behavioral and immunological parameters.

1985 • 235 citations

In Vivo β-Adrenergic Stimulation Suppresses Natural Killer Activity and Compromises Resistance to Tumor Metastasis in Rats

1998 • 210 citations

Prognostic risk assessment in primary breast cancer by behavioral and immunological parameters.

1985 • 181 citations

In vivo role of natural killer cells: involvement of large granular lymphocytes in the clearance of tumor cells in anti-asialo GM1-treated rats.

1983 • 166 citations

Natural killer cell activity in patients with hepatocellular carcinoma

1998 • 137 citations

The role of natural killer cells in the control of tumor growth and metastasis

1985 • 130 citations

Acute alcohol intoxication suppresses natural killer cell activity and promotes tumor metastasis

1996 • 130 citations

Sympathetic nervous system mediates central corticotropin-releasing factor induced suppression of natural killer cytotoxicity.

1990 • 128 citations

The Role of LGL/NK Cells in Surgery-Induced Promotion of Metastasis and Its Attenuation by Morphine

1994 • 127 citations

Evidence for the role of natural immunity in the control of metastatic spread of head and neck cancer

1987 • 123 citations

Large granular lymphocyte leukemia. A heterogeneous lymphocytic leukemia in F344 rats.

1983 • 121 citations

Surgical stress impairs natural killer cell programming of tumor for lysis in patients with sarcomas and other solid tumors

1992 • 102 citations

Social confrontation and tumor metastasis in rats: Defeat and β-adrenergic mechanisms

1996 • 100 citations

Effect of Morphine on Growth of Metastatic Colon Cancer In Vivo

1991 • 93 citations

PSYCHONEUROIMMUNOLOGY

1991 • 90 citations

In vivo treatment with monoclonal antibody 3.2.3 selectively eliminates natural killer cells in rats.

1990 • 89 citations

New frontiers in stress research : modulation of brain function

1998 • 71 citations

Perturbing the Organism: The Biology of Stressful Experience

1993 • 67 citations

An Immunopharmacological Analysis of Adrenaline-Induced Suppression of Human Natural Killer Cell Cytotoxicity

1989 • 61 citations

Increased susceptibility to metastasis during pro-oestrus/oestrus in rats: possible role of oestradiol and natural killer cells

1996 • 51 citations

Lytic units reconsidered: Pitfalls in calculation and usage

1990 • 45 citations

Immunological and hormonal responses to lung surgery during one-lung ventilation.

1993 • 43 citations

Exercise-induced alterations in natural killer cell number and function

1996 • 40 citations

Effect of restraint stress on immune system and experimental B16 melanoma metastasis in aged mice

1997 • 39 citations

Functional heterogeneity between NKR-P1bright/Lycopersicon esculentum lectin (L.E.)bright and NKR-P1bright/L.E.dim subpopulations of rat natural killer cells.

1992 • 34 citations

The Challenge of Postoperative Infections Does the Surgeon Make a Difference?

1997 • 33 citations

The Challenge of Postoperative Infections: Does the Surgeon Make a Difference?

1997 • 25 citations

Origin and functions of human natural killer cells

1994 • 24 citations

Sympathetic nervous system modulation of tumor metastases and host defense mechanisms

1992 • 21 citations

Modulation of Immunity and Neoplasia by Neuropeptides Released by Stressors

1991 • 12 citations

Immunoaugmentative therapy. An unproven cancer treatment

1993 • 10 citations

Large granular lymphocyte (LGL) lymphoproliferative diseases: Naturally cytotoxic tumors in man and experimental animals

1985 • 9 citations

Immunoaugmentative Therapy

1993 • 3 citations