Treatment of Gaucher disease with an enzyme inhibitor

Preparation of the active isomer of 1-phenyl-2-decanoylamino-3-morpholino-1-propanol, inhibitor of murine glucocerebroside synthetase

1987 • 254 citations

N-butyldeoxygalactonojirimycin inhibits glycolipid biosynthesis but does not affect N-linked oligosaccharide processing.

1994 • 175 citations

Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth.

1995 • 148 citations

Increased risk of cancer in patients with gaucher disease

1993 • 124 citations

Inhibition of Sphingolipid Synthesis by Cycloserine In Vitro and In Vivo

1984 • 110 citations

Effects of D‐threo‐PDMP, an inhibitor of glucosylceramide synthetase, on expression of cell surface glycolipid antigen and binding to adhesive proteins by B16 melanoma cells

1989 • 99 citations

A role for glycosphingolipid accumulation in the renal hypertrophy of streptozotocin-induced diabetes mellitus.

1993 • 95 citations

Antitumor activity via inhibition of glycosphingolipid biosynthesis

1987 • 74 citations

Epithelial glucosphingolipid expression as a determinant of bacterial adherence and cytokine production

1994 • 62 citations

A ceramide analogue (PDMP) inhibits glycolipid synthesis in fish embryos

1992 • 45 citations

Stimulation of liver growth and DNA synthesis by glucosylceramide

1988 • 44 citations

Rapid kidney changes resulting from glycosphingolipid depletion by treatment with a glucosyltransferase inhibitor

1991 • 28 citations

Metabolism of D-[3H]threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, an inhibitor of glucosylceramide synthesis, and the synergistic action of an inhibitor of microsomal monooxygenase

1991 • 26 citations

Control of kidney size by sex hormones: possible involvement of glucosylceramide

1992 • 26 citations

Effects of the glucosphingolipid synthesis inhibitor, PDMP, on lysosomes in cultured cells.

1994 • 26 citations

Human glucocerebrosidase catalyses transglucosylation between glucocerebroside and retinol

1994 • 23 citations

Brain Glucocerebrosidase in Gaucher's Disease

1982 • 18 citations

Changes in liver lipids after administration of 2‐decanoylamino‐3‐morpholinopropiophenone and chlorpromazine

1982 • 15 citations

Uptake by neuroblastoma cells of glucosylceramide, glucosylceramide glucosidase, its stimulator protein, and phosphatidylserine

1986 • 15 citations

Normalization of liver glucosylceramide levels in the “Gaucher” mouse by phosphatidylserine injection

1988 • 14 citations