Physical Interactions among Mcm Proteins and Effects of Mcm Dosage on DNA Replication in Saccharomyces cerevisiae

Experiments in molecular genetics

1972 • 28,260 citations

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

1992 • 1,279 citations

Mammalian Cell Fusion : Studies on the Regulation of DNA Synthesis and Mitosis

1970 • 759 citations

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1988 • 605 citations

Asynchronous Duplication of Chromosomes in Cultured Cells of Chinese Hamster

1960 • 530 citations

The Units of DNA Replication in Drosophila melanogaster Chromosomes

1974 • 518 citations

Eucaryotic DNA: Organization of the genome for replication

1978 • 476 citations

MUTANTS OF S. CEREVISIAE DEFECTIVE IN THE MAINTENANCE OF MINICHROMOSOMES

1984 • 419 citations

Isolation of ORC6 , a Component of the Yeast Origin Recognition Complex by a One-Hybrid System

1993 • 416 citations

A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication

1993 • 400 citations

Protein-DNA interactions at a yeast replication origin

1992 • 380 citations

Localization and Sequence Analysis of Yeast Origins of DNA Replication

1983 • 364 citations

Purification of an MCM-containing complex as a component of the DNA replication licensing system

1995 • 361 citations

A group of interacting yeast DNA replication genes.

1991 • 325 citations

Identification of the yeast MCM3-related protein as a component of xenopus DNA replication licensing factor

1995 • 280 citations

Gene Trap Tagging of PROLIFERA , an Essential MCM2-3-5 -Like Gene in Arabidopsis

1995 • 263 citations

BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication.

1995 • 234 citations

Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast.

1993 • 233 citations

Subcellular localization of yeast CDC46 varies with the cell cycle.

1990 • 226 citations

Autonomously replicating sequences in Saccharomyces cerevisiae.

1980 • 222 citations

MCM3 complex required for cell cycle regulation of DNA replication in vertebrate cells

1995 • 220 citations

Conditional-lethal mutations that suppress genetic defects in morphogenesis by altering structural proteins.

1975 • 212 citations

The origin recognition complex in silencing, cell cycle progression, and DNA replication.

1995 • 204 citations

A yeast origin of replication is activated late in S phase

1991 • 204 citations

Mcm2 and Mcm3, two proteins important for ARS activity, are related in structure and function.

1991 • 196 citations

The role of MCM/P1 proteins in the licensing of DNA replication.

1996 • 176 citations

Close association of a DNA replication origin and anARSelement on chromosome III of the yeast,Saccharomyces cerevisiae

1988 • 175 citations

DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period.

1994 • 173 citations

Evidence suggesting that the ARS elements associated with silencers of the yeast mating-type locus HML do not function as chromosomal DNA replication origins.

1991 • 169 citations

Cell cycle-regulated nuclear import and export of Cdc47, a protein essential for initiation of DNA replication in budding yeast.

1995 • 140 citations

The role of MCM proteins in the cell cycle control of genome duplication

1996 • 139 citations

The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication.

1990 • 138 citations

Ordered Assembly of Nucleoprotein Structures at the Bacteriophage λ Replication Origin during the Initiation of DNA Replication

1989 • 135 citations

The role of MCM/P1 proteins in the licensing of DNA replication

1996 • 131 citations

Interactions of human nuclear proteins P1Mcm3 and P1Cdc46.

1995 • 130 citations

The Nucleosome

1981 • 125 citations

The MCM2-3-5 proteins: are they replication licensing factors?

1994 • 124 citations

Time of Replication of ARS Elements along Yeast Chromosome III

1989 • 115 citations

Interactions of Human Nuclear Proteins P1Mcm3 and P1Cdc46

1995 • 103 citations

Replication fork rate and origin activation during the S phase of Saccharomyces cerevisiae.

1980 • 101 citations

CDC46/MCM5, a yeast protein whose subcellular localization is cell cycle-regulated, is involved in DNA replication at autonomously replicating sequences.

1992 • 99 citations

A Human Homologue of the Yeast Replication Protein Cdc21. Interactions with Other Mcm Proteins

1995 • 87 citations

Cell proliferation and DNA replication defects in a Drosophila MCM2 mutant.

1995 • 82 citations

Fiber autoradiography of replicating yeast DNA

1975 • 74 citations

A Human Homologue of the Yeast Replication Protein Cdc21

1995 • 63 citations

Cdc54 belongs to the Cdc46/Mcm3 family of proteins which are essential for initiation of eukaryotic DNA replication

1995 • 41 citations

REPLICATION OF SMALL CHROMOSOMAL DNAS IN YEAST

1980 • 36 citations

The murine replication protein P1 is differentially expressed during spermatogenesis.

1995 • 8 citations