DISCORDANT NEURAL TISSUE XENOGRAFTS SURVIVE LONGER IN IMMUNOGLOBULIN DEFICIENT MICE1

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

1991 • 1,783 citations

Perivascular Microglial Cells of the CNS Are Bone Marrow-Derived and Present Antigen in Vivo

1988 • 1,451 citations

Antigen-specific interaction between T and B cells

1985 • 1,396 citations

T‐lymphocyte entry into the central nervous system

1991 • 1,168 citations

Cytotoxicity of microglia

1993 • 1,042 citations

Man, apes, and Old World monkeys differ from other mammals in the expression of alpha-galactosyl epitopes on nucleated cells.

1988 • 924 citations

Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain

1985 • 881 citations

Neuropathological Evidence of Graft Survival and Striatal Reinnervation after the Transplantation of Fetal Mesencephalic Tissue in a Patient with Parkinson's Disease

1995 • 857 citations

Immunologically Privileged Sites

1978 • 815 citations

Cervical lymphatics, the blood-brain barrier and the immunoreactivity of the brain: a new view

1992 • 653 citations

Bilateral Fetal Mesencephalic Grafting in Two Patients with Parkinsonism Induced by 1-Methyl-4-Phenyl-L,2,3,6-Tetrahydropyridine (MPTP)

1992 • 499 citations

Short‐ and long‐term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease

1997 • 358 citations

Immunological aspects of grafting in the mammalian central nervous system. A review and speculative synthesis

1988 • 296 citations

Successful T cell priming in B cell-deficient mice.

1995 • 284 citations

The kinetics and morphological characteristics of the macrophage-microglial response to kainic acid-induced neuronal degeneration

1991 • 252 citations

Lazaroids improve the survival of grafted rat embryonic dopamine neurons.

1994 • 225 citations

THE BARRIER TO XENOTRANSPLANTATION

1991 • 205 citations

Antigen-Dependent Intrathecal Antibody Synthesis in the Normal Rat Brain: Tissue Entry and Local Retention of Antigen-Specific B Cells

1998 • 195 citations

Cross-species neural grafting in a rat model of Parkinson's disease

1982 • 192 citations

Cyclosporin A increases survival of cross-species intrastriatal grafts of embryonic dopamine-containing neurons

1985 • 186 citations

Enhanced antigen presentation using human Fc gamma receptor (monocyte/macrophage)-specific immunogens.

1992 • 177 citations

Intracerebral xenografts of dopamine neurons: the role of immunosuppression and the blood-brain barrier

1989 • 174 citations

Xenotransplantation of Porcine Fetal Ventral Mesencephalon in a Rat Model of Parkinson's Disease: Functional Recovery and Graft Morphology

1996 • 171 citations

THE MAIN INFILTRATING CELL IN XENOGRAFT REJECTION IS A CD4+ MACROPHAGE AND NOT A T LYMPHOCYTE

1995 • 145 citations

Temporal pattern of host responses against intrastriatal grafts of syngeneic, allogeneic or xenogeneic embryonic neuronal tissue in rats

1995 • 136 citations

Effects of cool storage on survival and function of intrastriatal ventral mesencephalic grafts

1991 • 120 citations

Neural transplantation

1997 • 119 citations

Mechanisms of allograft rejection in the rat brain

1990 • 110 citations

Leukocyte infiltration and glial reactions in xenografts of mouse brain tissue undergoing rejection in the adult rat brain. A light and electron microscopical immunocytochemical study

1991 • 105 citations

Neural xenotransplantation: Reconstruction of neuronal circuitry across species barriers

1994 • 105 citations

Antioxidant treatment protects striatal neurons against excitotoxic insults

1996 • 91 citations

XENOGRAFT REJECTION OF PORCINE ISLET-LIKE CELL CLUSTERS IN NORMAL AND NATURAL KILLER CELL-DEPLETED MICE1

1996 • 87 citations

Indefinite survival of neural xenografts induced with anti-CD4 monoclonal antibodies

1996 • 86 citations

Sequential Intracerebral Transplantation of Allogeneic and Syngeneic Fetal Dopamine-Rich Neuronal Tissue in Adult Rats: Will the First Graft be Rejected?

1993 • 71 citations

Histological signs of immune reactions against allogeneic solid fetal neural grafts in the mouse cerebellum depend on the MHC locus

1988 • 66 citations

Certain Host-Donor Rat Strain Combinations Do Not Reject Brain Allografts after Systemic Sensitization

1993 • 62 citations

Acute cellular xenograft rejection

1997 • 54 citations

XENOGRAFT REJECTION OF PORCINE ISLET-LIKE CELL CLUSTERS IN IMMUNOGLOBULIN- OR Fc-RECEPTOR ??-DEFICIENT MICE1

1996 • 53 citations

Chapter 16 The effect of site of transplantation and histocompatibility differences on the survival of neural tissue transplanted to the CNS of defined inbred rat strains

1990 • 48 citations

Contributions of Donor and Host Blood Vessels in CNS Allografts

1996 • 47 citations

Triple immunosuppression protects murine intracerebral, hippocampal xenografts in adult rat hosts: effects on cellular infiltration, major histocompatibility complex antigen induction and blood–brain barrier leakage

1997 • 44 citations

Immune reactions following systemic immunization prior or subsequent to intrastriatal transplantation of allogeneic mesencephalic tissue in adult rats

1995 • 43 citations

Robust survival of isolated bovine adrenal chromaffin cells following intrastriatal transplantation: a novel hypothesis of adrenal graft viability

1993 • 42 citations

Quinolinic acid‐induced inflammation in the striatum does not impair the survival of neural allografts in the rat

1998 • 40 citations

Fetal tissue transplanation in Parkinson’s disease

1998 • 40 citations

Specificities of human IgM and IgG anticarbohydrate xenoantibodies found in the sera of diabetic patients grafted with fetal pig islets

1994 • 37 citations

Integrity of the blood‐brain barrier in retinal xenografts is correlated with the immunological status of the host

1989 • 31 citations

Morphology of the avian brain

1891 • 29 citations

Fetal tissue transplantation in Parkinson's disease

1993 • 27 citations

FcγRII on Human B Cells Can Mediate Enhanced Antigen Presentation

1996 • 27 citations

Ontogenesis of embryonic porcine ventral mesencephalon in the perspective of its potential use as a xenograft in Parkinson's disease

1997 • 27 citations

B-CELL RECONSTITUTION AND XENOREACTIVE ANTI-PIG NATURAL ANTIBODY PRODUCTION IN SEVERE COMBINED IMMUNODEFICIENT MICE RECONSTITUTED WITH IMMUNOCOMPETENT B CELLS FROM VARYING SOURCES1

1998 • 25 citations

Role of anti‐donor antibody in the rejection of pig proislet xenografts in mice

1998 • 20 citations