Biallelic Inactivation of BRCA2 in Fanconi Anemia

Cancer Risks in BRCA2 Mutation Carriers

1999 • 1,477 citations

RING Finger Proteins

2000 • 1,216 citations

Interaction of the Fanconi Anemia Proteins and BRCA1 in a Common Pathway

2001 • 1,206 citations

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

1997 • 1,055 citations

Role of BRCA2 in Control of the RAD51 Recombination and DNA Repair Protein

2001 • 691 citations

Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas.

1996 • 637 citations

Stable Interaction between the Products of the BRCA1 and BRCA2 Tumor Suppressor Genes in Mitotic and Meiotic Cells

1998 • 625 citations

Involvement of Brca2 in DNA Repair

1998 • 624 citations

The emerging genetic and molecular basis of Fanconi anaemia

2001 • 578 citations

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos.

1997 • 537 citations

Convergence of the Fanconi Anemia and Ataxia Telangiectasia Signaling Pathways

2002 • 458 citations

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

1997 • 426 citations

Positional Cloning of a Novel Fanconi Anemia Gene, FANCD2

2001 • 414 citations

Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation.

2001 • 379 citations

Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification

1999 • 315 citations

Evidence for at least four Fanconi anaemia genes including FACC on chromosome 9

1992 • 305 citations

Evidence for at Least Eight Fanconi Anemia Genes

1997 • 292 citations

Brca2 is required for embryonic cellular proliferation in the mouse.

1997 • 285 citations

Fanconi's anemia and malignancies

1996 • 254 citations

Brca2 (XRCC11) Deficiency Results in Radioresistant DNA Synthesis and a Higher Frequency of Spontaneous Deletions

2002 • 252 citations

Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining

2001 • 251 citations

Fanconi anemia and DNA repair

2001 • 194 citations

Moderate frequency of BRCA1 and BRCA2 germ-line mutations in Scandinavian familial breast cancer.

1997 • 181 citations

Complementation Analysis in Fanconi Anemia: Assignment of the Reference FA-H Patient to Group A

2000 • 136 citations

Cancer susceptibility of mice with a homozygous deletion in the COOH-terminal domain of the Brca2 gene.

2002 • 113 citations

Reassessment of Cancer Predisposition of Fanconi Anemia Heterozygotes<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1980 • 74 citations

Studies of gene transfer and reversion to mitomycin C resistance in Fanconi anemia cells

1987 • 18 citations

Hepatocyte-mediated SCE induction by indirect mutagens: Importance of hepatocyte density and cell-to-cell contact

1987 • 5 citations