Regulation of the Murine αB-Crystallin/Small Heat Shock Protein Gene in Cardiac Muscle

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

1990 • 2,273 citations

Alpha-crystallin can function as a molecular chaperone.

1992 • 1,822 citations

The myoD Gene Family: Nodal Point During Specification of the Muscle Cell Lineage

1991 • 1,564 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

Differences and Similarities in DNA-Binding Preferences of MyoD and E2A Protein Complexes Revealed by Binding Site Selection

1990 • 957 citations

Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors

1986 • 883 citations

B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo

1985 • 859 citations

Production of Malignancy in Vitro. IV. The Mouse Fibroblast Cultures and Changes Seen in the Living Cells

1943 • 843 citations

Cytoplasmic activation of human nuclear genes in stable heterocaryons

1983 • 839 citations

A novel rapid assay for chloramphenicol acetyltransferase gene expression

1987 • 802 citations

MyoD family: a paradigm for development?

1990 • 776 citations

LENS CRYSTALLINS: THE EVOLUTION AND EXPRESSION OF PROTEINS FOR A HIGHLY SPECIALIZED TISSUE

1988 • 770 citations

An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter

1985 • 763 citations

Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line

1982 • 674 citations

Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis

1989 • 662 citations

The Heart and Cardiovascular System

1992 • 655 citations

Early expression of the myogenic regulatory gene, myf-5, in precursor cells of skeletal muscle in the mouse embryo

1991 • 548 citations

αB subunit of lens-specific protein α-crystallin is present in other ocular and non-ocular tissues

1989 • 538 citations

Alpha B-crystallin is a small heat shock protein.

1991 • 526 citations

Evolution of the alpha-crystallin/small heat-shock protein family.

1993 • 464 citations

Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. fos/jun expression is associated with sarcomere assembly; Egr-1 induction is primarily an alpha 1-mediated response.

1990 • 444 citations

Upstream regions of the human cardiac actin gene that modulate its transcription in muscle cells: presence of an evolutionarily conserved repeated motif.

1986 • 432 citations

Enzyme/crystallins: Gene sharing as an evolutionary strategy

1989 • 403 citations

Evolution of the Functional Human β-Actin Gene and Its Multi-Pseudogene Family: Conservation of Noncoding Regions and Chromosomal Dispersion of Pseudogenes

1985 • 378 citations

Expression of the murine alpha B-crystallin gene is not restricted to the lens.

1989 • 377 citations

Cell-type-specific contacts to immunoglobulin enhancers in nuclei

1985 • 341 citations

Muscle-specific expression of the cardiac alpha-actin gene requires MyoD1, CArG-box binding factor, and Sp1.

1990 • 334 citations

Cellular distribution of alpha B-crystallin in non-lenticular tissues.

1990 • 295 citations

The SRE: a growth factor responsive transcriptional regulator.

1990 • 287 citations

The muscle regulatory gene, Myf-6, has a biphasic pattern of expression during early mouse development.

1991 • 265 citations

Evolution of eye lens crystallins: the stress connection

1989 • 209 citations

Duplicated CArG Box Domains Have Positive and Mutually Dependent Regulatory Roles in Expression of the Human α-Cardiac Actin Gene

1987 • 192 citations

Xenopus cytoskeletal actin and human c-fos gene promoters share a conserved protein-binding site.

1987 • 181 citations

The Adenovirus Major Late Transcription Factor Activates the Rat γ-Fibrinogen Promoter

1987 • 177 citations

A MyoD1-independent muscle-specific enhancer controls the expression of the beta-myosin heavy chain gene in skeletal and cardiac muscle cells.

1991 • 175 citations

The sarcomeric actin CArG-binding factor is indistinguishable from the c-fos serum response factor.

1989 • 166 citations

Expression of a human placental alkaline phosphatase gene in transfected cells: use as a reporter for studies of gene expression.

1988 • 165 citations

The major late transcription factor binds to and activates the mouse metallothionein I promoter.

1987 • 160 citations

A complex array of positive and negative elements regulates the chicken alpha A-crystallin gene: involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins.

1994 • 146 citations

A conserved 28-base-pair element (HF-1) in the rat cardiac myosin light-chain-2 gene confers cardiac-specific and alpha-adrenergic-inducible expression in cultured neonatal rat myocardial cells.

1991 • 144 citations

Lens crystallins. Innovation associated with changes in gene regulation.

1992 • 143 citations

Multiple regulatory elements contribute differentially to muscle creatine kinase enhancer activity in skeletal and cardiac muscle.

1993 • 143 citations

The CArG promoter sequence is necessary for muscle-specific transcription of the cardiac actin gene in Xenopus embryos.

1989 • 140 citations

Alpha-crystallin/small heat shock protein has autokinase activity.

1994 • 138 citations

Developmental regulation of creatine kinase gene expression by myogenic factors in embryonic mouse and chick skeletal muscle

1991 • 125 citations

A combination of closely associated positive and negative cis-acting promoter elements regulates transcription of the skeletal alpha-actin gene.

1990 • 124 citations

A ubiquitous factor (HF-1a) and a distinct muscle factor (HF-1b/MEF-2) form an E-box-independent pathway for cardiac muscle gene expression.

1992 • 123 citations

The gene for the helix-loop-helix protein, Id, is specifically expressed in neural precursors

1992 • 115 citations

Lens Proteins and Their Genes

1991 • 113 citations

Analysis of the upstream regions governing expression of the chicken cardiac troponin T gene in embryonic cardiac and skeletal muscle cells.

1988 • 109 citations

Retention of lens specificity in long-term cultures of diploid rabbit lens epithelial cells

1986 • 107 citations

Pax-6 and lens-specific transcription of the chicken delta 1-crystallin gene.

1995 • 104 citations

Myocardial activation of the human cardiac alpha-actin promoter by helix-loop-helix proteins.

1992 • 96 citations

Cardiac alpha-crystallin

1990 • 95 citations

αB-Crystallin in Skeletal Muscle: Purification and Localization1

1991 • 90 citations

Fiber type- and position-dependent expression of a myosin light chain-CAT transgene detected with a novel histochemical stain for CAT.

1991 • 88 citations

Evidence that the transcription factor USF is a component of the human beta-globin locus control region heteromeric protein complex.

1993 • 88 citations

Nucleotide sequence and expression of the human skeletal ?-actin gene: Evolution of functional regulatory domains*1

1988 • 84 citations

Multiple CArG boxes in the human cardiac actin gene promoter required for expression in embryonic cardiac muscle cells developing in vitro from embryonal carcinoma cells.

1991 • 81 citations

The basic helix-loop-helix protein upstream stimulating factor regulates the cardiac ventricular myosin light-chain 2 gene via independent cis regulatory elements.

1994 • 79 citations

Synthesis of α-crystallin by a cell line derived from the lens of a transgenic animal

1990 • 76 citations

Identification of the human beta-actin enhancer and its binding factor.

1988 • 67 citations

The murine alpha B-crystallin/small heat shock protein enhancer: identification of alpha BE-1, alpha BE-2, alpha BE-3, and MRF control elements.

1993 • 65 citations

Expression of the Murine αB-Crystallin Gene in Lens and Skeletal Muscle: Identification of a Muscle-Preferred Enhancer

1991 • 64 citations

Cardiac alpha-crystallin

1990 • 62 citations

Multiple mRNAs of rat brain alpha-crystallin B chain result from alternative transcriptional initiation.

1990 • 59 citations

DNA-binding site for two skeletal actin promoter factors is important for expression in muscle cells.

1988 • 58 citations

Identification of a lens-specific regulatory region (LSR) of the murine αB-crystallin gene

1994 • 55 citations

CC Ar GG boxes, cis-acting elements with a dual specificity

1990 • 53 citations

Expression of the alpha-myosin heavy chain gene in the heart is regulated in part by an E-box-dependent mechanism.

1993 • 43 citations

The myosin light chain enhancer and the skeletal actin promoter share a binding site for factors involved in muscle-specific gene expression.

1991 • 42 citations

Identification and Characterization of a Factor That Binds to Two Human Sarcomeric Actin Promoters

1989 • 34 citations

Differential use of the regulatory elements of the αB-crystallin enhancer in cultured murine lung (MLg), lens (αTN4-1) and muscle (C2C12) cells

1995 • 33 citations

The E Box Is Essential for Activity of the Cardiac Actin Promoter in Skeletal but Not in Cardiac Muscle

1994 • 33 citations

Interaction of a protein factor within a thyroid hormone-sensitive region of rat alpha-myosin heavy chain gene.

1987 • 27 citations

Potential role of helix-loop-helix proteins in cardiac gene expression.

1993 • 22 citations

The leucine zipper is necessary for stabilizing a dimer of the helix-loop-helix transcription factor USF but not for maintenance of an elongated conformation.

1994 • 22 citations