NPAT links cyclin E–Cdk2 to the regulation of replication-dependent histone gene transcription

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1994 • 2,154 citations

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1994 • 2,071 citations

Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome

1999 • 1,774 citations

Human Cyclin E, a Nuclear Protein Essential for the G₁-to-S Phase Transition

1995 • 1,132 citations

Distinct Roles for Cyclin-Dependent Kinases in Cell Cycle Control

1993 • 1,096 citations

Formation and Activation of a Cyclin E-cdk2 Complex During the G ₁ Phase of the Human Cell Cycle

1992 • 1,046 citations

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

1992 • 1,031 citations

Cdk Phosphorylation Triggers Sequential Intramolecular Interactions that Progressively Block Rb Functions as Cells Move through G1

1999 • 1,028 citations

Acceleration of the G₁/S Phase Transition by Expression of Cyclins Dl and E with an Inducible System

1994 • 986 citations

Rb Interacts with Histone Deacetylase to Repress Transcription

1998 • 965 citations

Structure and Function in the Nucleus

1998 • 925 citations

Cyclin E-CDK2 is a regulator of p27Kip1.

1997 • 915 citations

Association of human cyclin E with a periodic G1-S phase protein kinase

1992 • 900 citations

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1994 • 798 citations

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation.

1993 • 795 citations

Cyclin-Dependent Regulation of G ₁ in Mammalian Fibroblasts

1993 • 767 citations

Regulation of NF-κB by Cyclin-Dependent Kinases Associated with the p300 Coactivator

1997 • 725 citations

Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

1990 • 723 citations

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system.

1994 • 659 citations

Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins

1990 • 656 citations

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

1987 • 516 citations

Requirement of Cdk2-Cyclin E Activity for Repeated Centrosome Reproduction in Xenopus Egg Extracts

1999 • 505 citations

THE REGULATION OF HISTONE SYNTHESIS IN THE CELL CYCLE

1991 • 498 citations

Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes

1991 • 493 citations

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

1997 • 435 citations

Cyclin-dependent kinase control of centrosome duplication

1999 • 423 citations

THE CYTOPLASMIC SYNTHESIS OF HISTONES IN HELA CELLS AND ITS TEMPORAL RELATIONSHIP TO DNA REPLICATION

1967 • 421 citations

Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin.

1991 • 369 citations

PRC1

1998 • 359 citations

Cell cycle–regulated phosphorylation of p220^NPATby cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription

2000 • 356 citations

An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription.

1993 • 342 citations

Nuclear bodies: multifaceted subdomains of the interchromatin space

1999 • 330 citations

The cdk2 kinase is required for the G1-to-S transition in mammalian cells.

1993 • 307 citations

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

1995 • 253 citations

Coiled bodies contain U7 small nuclear RNA and associate with specific DNA sequences in interphase human cells.

1995 • 244 citations

Mitotic Phosphorylation of the Oct-1 Homeodomain and Regulation of Oct-1 DNA Binding Activity

1991 • 237 citations

Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element.

1988 • 234 citations

Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry

1998 • 227 citations

Formation of the 3′ end of histone mRNA

1999 • 221 citations

Early events in DNA replication require cyclin E and are blocked by p21CIP1.

1995 • 197 citations

Activation of a cell-cycle-regulated histone gene by the oncogenic transcription factor IRF-2

1995 • 192 citations

Chromosome-specific alpha satellite DNA: nucleotide sequence analysis of the 2.0 kilobasepair repeat from the human X chromosome

1985 • 188 citations

Cell-cycle regulation of histone gene expression

1986 • 183 citations

Association between the nucleolus and the coiled body

1990 • 175 citations

Cyclin E Associates with BAF155 and BRG1, Components of the Mammalian SWI-SNF Complex, and Alters the Ability of BRG1 To Induce Growth Arrest

1999 • 163 citations

Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene.

1986 • 157 citations

The regulation of histone gene expression during the cell cycle

1991 • 149 citations

U1 and U2 small nuclear RNAs are present in nuclear speckles.

1992 • 141 citations

Stem-Loop Binding Protein Facilitates 3′-End Formation by Stabilizing U7 snRNP Binding to Histone Pre-mRNA

1999 • 128 citations

CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of transcription factor E2F.

1996 • 118 citations

BRCA1 Is Phosphorylated at Serine 1497 In Vivo at a Cyclin-Dependent Kinase 2 Phosphorylation Site

1999 • 115 citations

Histone 3' ends: essential and regulatory functions.

1992 • 115 citations

Purification of the human histone H4 gene-specific transcription factors H4TF-1 and H4TF-2.

1988 • 113 citations

The human histone gene cluster at the D6S105 locus

1997 • 112 citations

Mutagenesis of the pRB Pocket Reveals that Cell Cycle Arrest Functions Are Separable from Binding to Viral Oncoproteins

2000 • 112 citations

Changes in histone synthesis and modification at the beginning of mouse development correlate with the establishment of chromatin mediated repression of transcription

1997 • 108 citations

Structure andin vitrotranscription of a human H4 histone gene

1983 • 104 citations

Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts.

1996 • 102 citations

Cyclin E Associates with Components of the Pre-mRNA Splicing Machinery in Mammalian Cells

1998 • 91 citations

Cell-cycle regulatory sequences in a hamster histone promoter and their interactions with cellular factors

1987 • 89 citations

Histone H1 subtype-specific consensus elements mediate cell cycle-regulated transcription in vitro.

1989 • 88 citations

Microinjection of Anti-coilin Antibodies Affects the Structure of Coiled Bodies

1998 • 86 citations

Quantitative and qualitative changes in histone gene expression during early mouse embryo development.

1985 • 82 citations

Developmental regulation of chromatin composition during mouse embryogenesis: somatic histone H1 is first detectable at the 4-cell stage

1992 • 81 citations

Overlapping and CpG methylation-sensitive protein-DNA interactions at the histone H4 transcriptional cell cycle domain: distinctions between two human H4 gene promoters.

1992 • 80 citations

Cell cycle-dependent localization of the CDK2-cyclin E complex in Cajal (coiled) bodies

2000 • 77 citations

Identification of Promoter Elements Necessary for Transcriptional Regulation of a Human Histone H4 Gene In Vitro

1985 • 76 citations

Multiple Sequence Elements Are Required for Maximal in Vitro Transcription of a Human Histone H2B Gene

1986 • 73 citations

Regulation of histone gene expression

1992 • 67 citations

Delineation of a human histone H4 cell cycle element in vivo: the master switch for H4 gene transcription.

1994 • 66 citations

Biochemical demonstration of complex formation of histone pre-mRNA with U7 small nuclear ribonucleoprotein and hairpin binding factors.

1992 • 59 citations

The E2F Transcription Factor Activates a Replication-Dependent Human H2A Gene in Early S Phase of the Cell Cycle

1996 • 54 citations

Accumulation of E2F-4·DP-1 DNA Binding Complexes Correlates with Induction of dhfr Gene Expression during the G1 to S Phase Transition

1997 • 39 citations

Identification of AP-2 as an interactive target of Rb and a regulator of the G1/S control element of the hamster histone H3.2 promoter

1998 • 30 citations

H1TF2A, the large subunit of a heterodimeric, glutamine-rich CCAAT-binding transcription factor involved in histone H1 cell cycle regulation.

1994 • 30 citations

Identification of promoter elements necessary for transcriptional regulation of a human histone H4 gene in vitro.

1985 • 29 citations

Proviral Inactivation of the Npat Gene of Mpv 20 Mice Results in Early Embryonic Arrest

1997 • 27 citations

Single-copy flanking sequences in human histone gene clusters map to chromosomes 1 and 6

1991 • 27 citations

RNA polymerase II transcription factors H4TF-1 and H4TF-2 require metal to bind specific DNA sequences.

1987 • 24 citations

Regulation of the Mouse Histone H2A.X Gene Promoter by the Transcription Factor E2F and CCAAT Binding Protein

1995 • 20 citations

Overlapping and CpG Methylation-Sensitive Protein-DNA Interactions at the Histone H4 Transcriptional Cell Cycle Domain: Distinctions between Two Human H4 Gene Promoters

1992 • 18 citations

Immunological analysis of chromatin: FIS and CHIPS

1998 • 16 citations

H1TF2A, the Large Subunit of a Heterodimeric, Glutamine-Rich CCAAT-Binding Transcription Factor Involved in Histone H1 Cell Cycle Regulation

1994 • 11 citations

RNA Polymerase II Transcription Factors H4TF-1 and H4TF-2 Require Metal to Bind Specific DNA Sequences

1987 • 8 citations