Cholecystokinin modulates the aversive component of morphine withdrawal syndrome in rats

Evidence for coexistence of dopamine and CCK in meso-limbic neurones

1980 • 696 citations

Evidence for the Neuropeptide Cholecystokinin as an Antagonist of Opiate Analgesia

1983 • 582 citations

Biochemical and pharmacological characterization of an extremely potent and selective nonpeptide cholecystokinin antagonist.

1986 • 544 citations

Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity.

1990 • 501 citations

Drug reinforcement studied by the use of place conditioning in rat

1982 • 482 citations

Depression of Mesolimbic Dopamine Transmission and Sensitization to Morphine During Opiate Abstinence

1992 • 224 citations

Cholecystokinin peptides produce marked reduction of dopamine turnover in discrete areas in the rat brain following intraventricular injection

1980 • 196 citations

Profound decrease of mesolimbic dopaminergic neuronal activity in morphine withdrawn rats.

1995 • 167 citations

Cholecystokinin Modulates the Release of Dopamine from the Anterior and Posterior Nucleus Accumbens by Two Different Mechanisms

1991 • 150 citations

Modulation of opioid antinociception by CCK at the supraspinal level: evidence of regulatory mechanisms between CCK and enkephalin systems in the control of pain

1993 • 90 citations

Cholecystokinin B antagonists strongly potentiate antinociception mediated by endogenous enkephalins.

1994 • 90 citations

Cholecystokinin octapeptides alter the release of endogenous dopamine from the rat nucleus accumbens in vitro.

1986 • 85 citations

Heterogeneity of CCK-B receptors involved in animal models of anxiety

1994 • 79 citations

Tolerance and selective cross-tolerance to the motivational effects of opioids

1988 • 64 citations

Morphine place conditioning is differentially affected by CCKA and CCKB receptor antagonists

1992 • 62 citations

The CCKB receptor antagonist, L-365,260, elicits antidepressant-type effects in the forced-swim test in mice

1994 • 56 citations

Occurrence of two cholecystokinin binding sites in guinea-pig brain cortex

1986 • 55 citations

Antidepressant‐like effects of CCK_B antagonists in mice: antagonism by naltrindole

1994 • 52 citations

The CCKB antagonist PD-134,308 facilitates rewarding effects of endogenous enkephalins but does not induce place preference in rats

1996 • 51 citations

A new, highly selective CCK-B receptor radioligand ([3H][N-methyl-Nle28,31]CCK26-33): evidence for CCK-B receptor heterogeneity.

1990 • 51 citations

Effects of CCK8 and of the CCKB-selective agonist BC264 on extracellular dopamine content in the anterior and posterior nucleus accumbens: a microdialysis study in freely moving rats

1993 • 50 citations

Conditioned place preference produced by infusion of Met-enkephalin into the medial preoptic area

1991 • 50 citations

Differential involvement of CCK-A and CCK-B receptors in the regulation of locomotor activity in the mouse

1991 • 46 citations

Opposite role of CCKA and CCKB receptors in the modulation of endogenous enkephalin antidepressant-like effects

1995 • 45 citations

The transfer of rats from a familiar to a novel environment prolongs the increase of extracellular dopamine efflux induced by CCK8 in the posterior nucleus accumbens

1995 • 41 citations

Protein Kinases in the Rat Nucleus Accumbens are Involved in the Aversive Component of Opiate Withdrawal

1996 • 39 citations

Cholecystokinin OctapeptideIn VitroandEx VivoStrongly Modulates Striatal Dopamine D₂Receptors in Rat Forebrain Sections

1995 • 31 citations

Measurement of central nervous system activity of systemically administered CCKB receptor antagonists by ex vivo binding

1994 • 27 citations

Inhibition of morphine withdrawal by the association of RB 101, an inhibitor of enkephalin catabolism, and the CCK_B antagonist PD‐134,308

1995 • 26 citations

CCK‐B Antagonists Exhibit Antidepressant‐Like Effects and Potentiate Endogenous Enkephalin Analgesia

1994 • 10 citations