Induction Therapy in the Modern Era of Combined-Modality Therapy for Locally Advanced Head and Neck Cancer

Cancer Statistics, 2007

2007 • 7,372 citations

Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck

2006 • 4,800 citations

Postoperative Concurrent Radiotherapy and Chemotherapy for High-Risk Squamous-Cell Carcinoma of the Head and Neck

2004 • 2,992 citations

Postoperative Irradiation with or without Concomitant Chemotherapy for Locally Advanced Head and Neck Cancer

2004 • 2,842 citations

Induction Chemotherapy plus Radiation Compared with Surgery plus Radiation in Patients with Advanced Laryngeal Cancer

1991 • 2,563 citations

Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data

2000 • 2,411 citations

An Intergroup Phase III Comparison of Standard Radiation Therapy and Two Schedules of Concurrent Chemoradiotherapy in Patients With Unresectable Squamous Cell Head and Neck Cancer

2002 • 1,679 citations

Cisplatin and Fluorouracil Alone or with Docetaxel in Head and Neck Cancer

2007 • 1,629 citations

Cisplatin, Fluorouracil, and Docetaxel in Unresectable Head and Neck Cancer

2007 • 1,612 citations

Larynx Preservation in Pyriform Sinus Cancer: Preliminary Results of a European Organization for Research and Treatment of Cancer Phase III Trial

1996 • 1,305 citations

Randomized Trial of Radiation Therapy Versus Concomitant Chemotherapy and Radiation Therapy for Advanced-Stage Oropharynx Carcinoma

1999 • 1,063 citations

Final Results of the 94–01 French Head and Neck Oncology and Radiotherapy Group Randomized Trial Comparing Radiotherapy Alone With Concomitant Radiochemotherapy in Advanced-Stage Oropharynx Carcinoma

2003 • 868 citations

Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data

2000 • 566 citations

Phase III Trial of Initial Chemotherapy in Stage III or IV Head and Neck Cancers: a Study by the Gruppo di Studio sui Tumori della Testa e del Collo

1994 • 416 citations

Intensified hyperfractionated accelerated radiotherapy limits the additional benefit of simultaneous chemotherapy—results of a multicentric randomized German trial in advanced head-and-neck cancer

2001 • 358 citations

Human papillomavirus type 16 and squamous cell carcinoma of the head and neck.

2002 • 281 citations

Randomized trial of neoadjuvant chemotherapy in oropharyngeal carcinoma

2000 • 250 citations

Docetaxel (Taxotere®): An active drug for the treatment of patients with advanced squamous cell carcinoma of the head and neck

1994 • 249 citations

Docetaxel: an active drug for squamous cell carcinoma of the head and neck.

1996 • 233 citations

Randomized comparison of neoadjuvant cisplatin and fluorouracil infusion followed by radiation versus concomitant treatment in advanced head and neck cancer.

1994 • 202 citations

Randomized Phase III Trial of Neoadjuvant Chemotherapy in Head and Neck Cancer: 10-Year Follow-Up

2004 • 189 citations

Long-term results of Intergroup RTOG 91–11: A phase III trial to preserve the larynx—Induction cisplatin/5-FU and radiation therapy versus concurrent cisplatin and radiation therapy versus radiation therapy

2006 • 176 citations

Concomitant Boost Radiation Plus Concurrent Cisplatin for Advanced Head and Neck Carcinomas: Radiation Therapy Oncology Group Phase II Trial 99-14

2005 • 164 citations

Multicenter Phase I-II Trial of Docetaxel, Cisplatin, and Fluorouracil Induction Chemotherapy for Patients With Locally Advanced Squamous Cell Cancer of the Head and Neck

2001 • 158 citations

Phase II Trial of Docetaxel, Cisplatin, Fluorouracil, and Leucovorin as Induction for Squamous Cell Carcinoma of the Head and Neck

1999 • 128 citations

Induction chemotherapy with docetaxel, cisplatin, fluorouracil, and leucovorin for squamous cell carcinoma of the head and neck: a phase I/II trial.

1998 • 116 citations

End points for new agents in induction chemotherapy for locally advanced head and neck cancers

2002 • 105 citations

Docetaxel, cisplatin, and 5‐fluorouracil‐based induction chemotherapy in patients with locally advanced squamous cell carcinoma of the head and neck

2003 • 92 citations

Efficacy of intensified hyperfractionated and accelerated radiotherapy and concurrent chemotherapy with carboplatin and 5-fluorouracil: Updated results of a randomized multicentric trial in advanced head-and-neck cancer

2006 • 90 citations

Docetaxel, cisplatin and 5-fluorouracil in patients with locally advanced unresectable head and neck cancer: a phase I–II feasibility study

2004 • 86 citations

Randomized phase III trial comparing induction chemotherapy using cisplatin (P) fluorouracil (F) with or without docetaxel (T) for organ preservation in hypopharynx and larynx cancer. Preliminary results of GORTEC 2000–01

2006 • 72 citations

Phase I/II Trial of Outpatient Docetaxel, Cisplatin, 5-Fluorouracil, Leucovorin (opTPFL) as Induction for Squamous Cell Carcinoma of the Head and Neck (SCCHN)

2002 • 57 citations

Evaluation of High-Dose Cisplatin and 5-FU Infusion as Initial Therapy in Advanced Head and Neck Cancer

1988 • 48 citations

Paclitaxel (Taxol) for the treatment of head and neck cancer.

1994 • 41 citations

Neoadjuvant chemotherapy in head and neck cancer: Should it be revisited?

2007 • 39 citations

Phase III study on larynx preservation comparing induction chemotherapy and radiotherapy versus alternating chemoradiotherapy in resectable hypopharynx and larynx cancers. EORTC protocol 24954–22950

2007 • 21 citations

Impact on quality of life (QoL) of the addition of docetaxel (T) to neoadjuvant cisplatin plus 5-fluorouracil treatment in patients with locally advanced unresectable squamous cell carcinoma of the head and neck (SCCHN): EORTC study 24971

2006 • 19 citations

Is laryngeal preservation (LP) with induction chemotherapy (ICT) safe in the treatment of hypopharyngeal SCC? Final results of the phase III EORTC 24891 trial

2004 • 15 citations