Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease

“Mini-mental state”

1975 • 82,784 citations

Clinical diagnosis of Alzheimer's disease

1984 • 27,279 citations

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

1993 • 8,888 citations

The Neuropsychiatric Inventory

1994 • 7,026 citations

Vascular dementia

1993 • 4,707 citations

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

1993 • 4,145 citations

A new rating scale for Alzheimer's disease

1984 • 3,948 citations

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

1993 • 3,693 citations

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

1995 • 3,603 citations

Preclinical Evidence of Alzheimer's Disease in Persons Homozygous for the ε4 Allele for Apolipoprotein E

1996 • 1,320 citations

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

1993 • 940 citations

Donepezil for dementia due to Alzheimer's disease

2018 • 863 citations

Development of a Functional Measure for Persons With Alzheimer’s Disease: The Disability Assessment for Dementia

1999 • 850 citations

A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD

2001 • 723 citations

APOLIPOPROTEIN E ALLELES AS RISK FACTORS IN ALZHEIMER'S DISEASE

1996 • 677 citations

Hyperinsulinemia and risk of Alzheimer disease

2004 • 666 citations

Association of diabetes mellitus and dementia: The Rotterdam Study

1996 • 650 citations

Validity and Reliability of the Alzheimerʼs Disease Cooperative Study-Clinical Global Impression of Change

1997 • 620 citations

Effects of intranasal insulin on cognition in memory-impaired older adults: Modulation by APOE genotype

2005 • 597 citations

Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease.

1995 • 596 citations

Preserved Cognition in Patients With Early Alzheimer Disease and Amnestic Mild Cognitive Impairment During Treatment With Rosiglitazone: A Preliminary Study

2005 • 584 citations

Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone

2004 • 576 citations

Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications

2005 • 566 citations

Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation.

1997 • 524 citations

Rivastigmine for Alzheimer's disease

2015 • 522 citations

Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer’s Disease Treatment Studies

2002 • 477 citations

The Role of Insulin Resistance in the Pathogenesis of Alzheimer??s Disease

2003 • 390 citations

Neuron-Specific Apolipoprotein E4 Proteolysis Is Associated with Increased Tau Phosphorylation in Brains of Transgenic Mice

2004 • 370 citations

Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

2001 • 366 citations

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

2003 • 328 citations

Transport of Insulin Across the Blood-Brain Barrier: Saturability at Euglycemic Doses of Insulin

1997 • 312 citations

Validity and Reliability of the Alzheimer’s Disease Cooperative Study-Clinical Global Impression of Change (ADCS-CGIC)

1997 • 310 citations

Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity

2005 • 300 citations

Peroxisome proliferator‐activated receptor‐γ agonists prevent experimental autoimmune encephalomyelitis

2002 • 286 citations

Longitudinal association of vascular and Alzheimer's dementias, diabetes, and glucose tolerance

1999 • 227 citations

Galantamine for Alzheimer's disease

2004 • 187 citations

Mitochondrial damage in Alzheimer's disease varies with apolipoprotein E genotype

2000 • 175 citations

Donepezil Therapy in Clinical Practice

2000 • 166 citations

Peroxisome Proliferator-activated Receptor γ Thiazolidinedione Agonists Increase Glucose Metabolism in Astrocytes

2003 • 157 citations

Rivastigmine for Alzheimer's disease

2000 • 152 citations

Thiazolidinedione Activation of Peroxisome Proliferator-activated Receptor γ Can Enhance Mitochondrial Potential and Promote Cell Survival

2002 • 115 citations

Lack of association between apolipoprotein E genoype and ischaemic stroke in a Scottish population

2001 • 64 citations

Comparison of adipose tissue changes following administration of rosiglitazone in the dog and rat

2001 • 43 citations

Clinical and Neuroimaging Features of Familial Alzheimer's Diseasea

1996 • 38 citations

Deleted Work

1955 • 0 citations