Radiation-Induced Cognitive Impairments are Associated with Changes in Indicators of Hippocampal Neurogenesis

Developments of a water-maze procedure for studying spatial learning in the rat

1984 • 6,896 citations

Neurogenesis in the adult human hippocampus

1998 • 6,181 citations

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

1999 • 3,805 citations

More hippocampal neurons in adult mice living in an enriched environment

1997 • 3,476 citations

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

1996 • 3,079 citations

Functional neurogenesis in the adult hippocampus

2002 • 2,813 citations

The linear-quadratic formula and progress in fractionated radiotherapy

1989 • 2,150 citations

Learning enhances adult neurogenesis in the hippocampal formation

1999 • 2,134 citations

Neurogenesis in the adult is involved in the formation of trace memories

2001 • 2,014 citations

Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat

1993 • 1,215 citations

Irradiation induces neural precursor-cell dysfunction

2002 • 1,189 citations

Therapeutic irradiation and brain injury

1980 • 985 citations

Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice

2002 • 954 citations

Ethologically-based animal models of anxiety disorders

1990 • 841 citations

Enriched environment increases neurogenesis in the adult rat dentate gyrus and improves spatial memory

1999 • 840 citations

Stress and hippocampal neurogenesis

1999 • 799 citations

The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis

2002 • 752 citations

Multipotent progenitor cells in the adult dentate gyrus

1998 • 722 citations

Neurobehavioral sequelae of cranial irradiation in adults: a review of radiation-induced encephalopathy.

1994 • 713 citations

Extreme sensitivity of adult neurogenesis to low doses of X-irradiation.

2003 • 643 citations

Adult-generated neurons in the dentate gyrus send axonal projections to field CA3 and are surrounded by synaptic vesicles

1999 • 561 citations

Analysis of neurogenesis and programmed cell death reveals a self-renewing capacity in the adult rat brain

2000 • 497 citations

Arrested neuronal proliferation and impaired hippocampal function following fractionated brain irradiation in the adult rat

2003 • 476 citations

Inducible and Reversible Enhancement of Learning, Memory, and Long-Term Potentiation by Genetic Inhibition of Calcineurin

2001 • 464 citations

Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal ltp in the range of the θ frequency

1995 • 464 citations

Why New Neurons? Possible Functions for Adult Hippocampal Neurogenesis

2002 • 464 citations

Neuropsychological effects of cranial radiation: current knowledge and future directions

1995 • 432 citations

Evidence that granule cells generated in the dentate gyrus of adult rats extend axonal projections

1988 • 429 citations

Doublecortin expression in the adult rat telencephalon

2001 • 422 citations

Associative Memory Formation Increases the Observation of Dendritic Spines in the Hippocampus

2003 • 397 citations

Hippocampal lesions cause learning deficits in inbred mice in the Morris water maze and conditioned-fear task.

1997 • 362 citations

Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: Increased susceptibility of females

1998 • 354 citations

Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients

2001 • 307 citations

X-irradiation causes a prolonged reduction in cell proliferation in the dentate gyrus of adult rats

2000 • 302 citations

Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains

1999 • 291 citations

Long-term intellectual outcome in children with posterior fossa tumors according to radiation doses and volumes

1999 • 280 citations

Behavioral profiles of inbred strains on novel olfactory, spatial and emotional tests for reference memory in mice

2002 • 275 citations

Pathogenesis of Irradiation-Induced Cognitive Dysfunction

1996 • 266 citations

Time- and dose-related changes in the white matter of the rat brain after single doses of X rays

1988 • 253 citations

Of Mice and Mazes: Similarities Between Mice and Rats on Dry Land But Not Water Mazes

1996 • 247 citations

LTP saturation and spatial learning disruption: effects of task variables and saturation levels

1994 • 218 citations

Ionizing radiation-induced apoptosis of proliferating stem cells in the dentate gyrus of the adult rat hippocampus

1999 • 202 citations

Neuropsychologic effects of cranial irradiation, intrathecal methotrexate, and systemic methotrexate in childhood cancer.

1994 • 193 citations

Spatial Long-Term Memory Is Related to Mossy Fiber Synaptogenesis

2001 • 183 citations

Influence of task parameters on rotarod performance and sensitivity to ethanol in mice

2003 • 176 citations

Mice are not little rats

2000 • 159 citations

Adaptation of the circular platform spatial memory task for mice: use in detecting cognitive impairment in the APPSW transgenic mouse model for Alzheimer’s disease

1999 • 154 citations

Learning and adult neurogenesis: Survival with or without proliferation?

2003 • 147 citations

Neurocognitive effects of therapeutic irradiation for base of skull tumors

2000 • 146 citations

Ibotenate lesions of the hippocampus impair spatial learning but not contextual fear conditioning in mice

1998 • 134 citations

Effects of radiation therapy on neuropsychological functioning in patients with nasopharyngeal carcinoma.

1989 • 128 citations

Hypothalamic–Pituitary–Adrenal Dysfunction inApoe^−/−Mice: Possible Role in Behavioral and Metabolic Alterations

2000 • 127 citations

Late behavioural and neuropathological effects of local brain irradiation in the rat

1998 • 97 citations

Selective vulnerability to radiation in the hippocampal dentate granule cells

2000 • 73 citations

Repair Capacity of Adult Rat Glial Progenitor Cells Determined by anin VitroClonogenic Assay afterin Vitroorin VivoFractionated Irradiation

1993 • 65 citations

The effects of X-irradiation on the postnatally-forming granule cell populations in the olfactory bulb, hippocampus, and cerebellum of the rat

1975 • 63 citations

Cognitive Dysfunction and Histological Findings in Adult Rats One Year After Whole Brain Irradiation.

2001 • 57 citations

Hippocampal dysfunction and behavioral deficit in the water maze in mice: An unresolved issue?

2002 • 55 citations

Brain tumors in children and adolescents—III. effects of radiation and hormone status on intelligence and on working, associative and serial-order memory

1992 • 54 citations

Radiation-induced cognitive dysfunction: An experimental model in the old rat

1995 • 52 citations

A prospective study of cognitive functioning following low-dose cranial radiation for bone marrow transplantation.

1992 • 48 citations

Adult‐generated neurons in the dentate gyrus send axonal projections to field CA3 and are surrounded by synaptic vesicles

1999 • 43 citations

Learning impairments of hippocampal-lesioned mice in a paddling pool.

2002 • 39 citations

Target cells of apoptosis in the adult murine dentate gyrus and O4 immunoreactivity after ionizing radiation

2000 • 22 citations

Deleted Work

1955 • 0 citations