Sulfasalazine in early rheumatoid arthritis. A 48‐week double‐blind, prospective, placebo‐controlled study

THERAPEUTIC CRITERIA IN RHEUMATOID ARTHRITIS

1949 • 2,904 citations

CLINICAL STUDIES WITH AN ARTICULAR INDEX FOR THE ASSESSMENT OF JOINT TENDERNESS IN PATIENTS WITH RHEUMATOID ARTHRITIS

1968 • 1,360 citations

A double‐blind, placebo‐controlled trial

1986 • 1,281 citations

Preliminary criteria for clinical remission in rheumatoid arthritis

1981 • 806 citations

The Effect of a Hormone of the Adrenal Cortex (17-hydroxy-11-dehydrocorticosterone: Compound E) and of Pituitary Adrenocorticotropic Hormone on Rheumatoid Arthritis

1949 • 781 citations

Diagnostic Criteria for Rheumatoid Arthritis: 1958 Revision

1959 • 685 citations

LONG-TERM OUTCOME OF TREATING RHEUMATOID ARTHRITIS: RESULTS AFTER 20 YEARS

1987 • 593 citations

EFFECTS OF HYDROXYCHLOROQUINE AND SULPHASALAZINE ON PROGRESSION OF JOINT DAMAGE IN RHEUMATOID ARTHRITIS

1989 • 568 citations

The comparative efficacy and toxicity of second‐line drugs in rheumatoid arthritis results of two metaanalyses

1990 • 471 citations

Biannual Radiographic Assessments of Hands and Feet in a Three‐Year Prospective Followup of Patients with Early Rheumatoid Arthritis

1992 • 441 citations

Salazopyrin, a new sulfanilamide preparation. A. Therapeutic Results in Rheumatic Polyarthritis. B. Therapeutic Results in Ulcerative Colitis. C. Toxic Manifestations in Treatment with Sulfanilamide Preparations.

1942 • 358 citations

Evidence of significant radiographic damage in rheumatoid arthritis within the first 2 years of disease.

1989 • 346 citations

Taking mortality in rheumatoid arthritis seriously--predictive markers, socioeconomic status and comorbidity.

1986 • 328 citations

Radiographic changes in early rheumatoid disease.

1977 • 304 citations

Remodeling the pyramid--a concept whose time has come.

1989 • 246 citations

Prediction of erosiveness and rate of development of new erosions in early rheumatoid arthritis.

1988 • 222 citations

Does Drug Therapy Slow Radiographic Deterioration in Rheumatoid Arthritis?

1983 • 189 citations

Sulphasalazine in rheumatoid arthritis.

1980 • 176 citations

Sulphasalazine in rheumatoid arthritis: a double blind comparison of sulphasalazine with placebo and sodium aurothiomalate.

1983 • 168 citations

Early rheumatoid arthritis —onset, course, and outcome over 2 years

1990 • 151 citations

Sulphasalazine for rheumatoid arthritis: toxicity in 774 patients monitored for one to 11 years.

1986 • 141 citations

Which component of sulphasalazine is active in rheumatoid arthritis?

1985 • 138 citations

The effect of a hormone of the adrenal cortex ( 17-hydroxy-11-dehydrocortisone: compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis: preliminary report

1949 • 137 citations

Long-term treatment of rheumatoid arthritis with sulphasalazine, gold, or penicillamine: a comparison using life-table methods.

1987 • 137 citations

Comparison between penicillamine and sulphasalazine in rheumatoid arthritis: Leeds-Birmingham trial.

1983 • 124 citations

A controlled trial comparing sulfasalazine, gold sodium thiomalate, and placebo in rheumatoid arthritis

1988 • 116 citations

Auranofin improves outcome in early rheumatoid arthritis. Results from a 2-year, double blind placebo controlled study.

1988 • 91 citations

Sulphasalazine: a safe, effective agent for prolonged control of rheumatoid arthritis. A comparison with sodium aurothiomalate.

1985 • 89 citations

Salazopyrin in rheumatoid arthritis

1978 • 87 citations

Salazopyrin in the Treatment of Rheumatoid Arthritis

1949 • 85 citations

Effect of acetylator phenotype on efficacy and toxicity of sulphasalazine in rheumatoid arthritis.

1985 • 67 citations

A double blind comparative study of sulphasalazine and hydroxychloroquine in rheumatoid arthritis: evidence of an earlier effect of sulphasalazine.

1989 • 64 citations

Effect of sulphasalazine on the radiological progression of rheumatoid arthritis.

1987 • 61 citations

Effect of sulphasalazine and its active metabolite, 5-amino-salicylic acid, on toxic oxygen metabolite production by neutrophils.

1989 • 59 citations

LONG-TERM SECOND-LINE TREATMENT: A PROSPECTIVE DRUG SURVIVAL STUDY

1992 • 58 citations

Value of joint scintigraphy in the prediction of erosiveness in early rheumatoid arthritis.

1988 • 56 citations

Survival in rheumatoid arthritis

1987 • 55 citations

SHOULD DISEASE-MODIFYING AGENTS BE USED IN MILD RHEUMATOID ARTHRITIS?

1991 • 50 citations

Bone resorption by cells isolated from rheumatoid synovium.

1992 • 50 citations

The radiographic criterion in the 1987 revised criteria for rheumatoid arthritis. Reassessment in a prospective study of early disease

1992 • 37 citations

Is the beneficial effect of sulfasalazine due to inhibition of synovial neovascularization?

1991 • 33 citations

SULPHASALAZINE FOR RHEUMATOID ARTHRITIS: RELATIONSHIP BETWEEN DOSE, ACETYLATOR PHENOTYPE AND RESPONSE TO TREATMENT

1986 • 29 citations

Clinical and laboratory effects of prolonged therapy with sulfasalazine, gold or penicillamine: the effects of disease duration on treatment response.

1990 • 28 citations

A prospective study of early onset rheumatoid arthritis over fifteen years: prognostic features and outcome

1987 • 26 citations

Influence of Acetylator Status on Sulphasalazine Efficacy and Toxicity in Patients with Rheumatoid Arthrftis

1992 • 25 citations

Degree and Extent of Response to Sulphasalazine or Penicillamine Therapy for Rheumatoid Arthritis: Results from a Routine Clinical Environment over a Two-Year Period

1990 • 25 citations

Inhibition of cell mediated cytotoxicity by sulphasalazine: effect of in vivo treatment with 5-aminosalicylic acid and sulphasalazine on in vitro natural killer cell activity.

1990 • 23 citations

Effect of sulphasalazine and sulphapyridine on neutrophil superoxide production: role of cytosolic free calcium.

1990 • 23 citations

Prospective trial comparing the use of sulphasalazine and auranofin as second line drugs in patients with rheumatoid arthritis.

1992 • 23 citations

Sulphasalazine inhibition of human granulocyte activation by inhibition of second messenger compounds.

1992 • 21 citations

Classification of antirheumatic drugs. A new proposal

1992 • 18 citations

Auranofin (SK&F) in Early Rheumatoid Arthritis: Results from a 24-month Double-blind, Placebo-controlled StudyEffect on Clinical and Biochemical Assessments

1989 • 15 citations

The use of sulphasalazine as a disease modifying antirheumatic drug

1990 • 14 citations

Seronegative arthritis and the bowel

1989 • 10 citations