Transgene Repeat Arrays Interact With Distant Heterochromatin and Cause Silencing in cis and trans

HETEROCHROMATIN AND GENE EXPRESSION IN DROSOPHILA

1995 • 526 citations

Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila

1994 • 506 citations

Inactivation of gene expression in plants as a consequence of specific sequence duplication.

1994 • 462 citations

Perturbation of Nuclear Architecture by Long-Distance Chromosome Interactions

1996 • 425 citations

Locus Control Region Function and Heterochromatin-Induced Position Effect Variegation

1996 • 373 citations

Mapping simple repeated DNA sequences in heterochromatin of Drosophila melanogaster.

1993 • 345 citations

Heterochromatin Effects on the Frequency and Duration of LCR-Mediated Gene Transcription

1996 • 328 citations

The enhancer of position-effect variegation of Drosophila, E(var)3-93D, codes for a chromatin protein containing a conserved domain common to several transcriptional regulators.

1993 • 178 citations

The vagaries of variegating transgenes

1996 • 165 citations

Variegated transgene expression in mouse mammary gland is determined by the transgene integration locus.

1996 • 153 citations

The role of heterochromatin in the expression of a heterochromatic gene, the rolled locus of Drosophila melanogaster.

1993 • 127 citations

RIGS (repeat-induced gene silencing) in Arabidopsis is transcriptional and alters chromatin configuration.

1996 • 126 citations

Chapter 22 Position-Effect Variegation—An Assay for Nonhistone Chromosomal Proteins and Chromatin Assembly and Modifying Factors

1991 • 104 citations

Trans-inactivation of the Drosophila brown gene: evidence for transcriptional repression and somatic pairing dependence.

1989 • 99 citations

Synapsis-dependent allelic complementation at the decapentaplegic gene complex in Drosophila melanogaster.

1982 • 95 citations

Copy Number and Orientation Determine the Susceptibility of a Gene to Silencing by Nearby Heterochromatin in Drosophila

1996 • 94 citations

Towards an understanding of position effect variegation

1989 • 90 citations

Nuclear organization and gene expression: homologous pairing and long-range interactions

1997 • 86 citations

Cis-effects of heterochromatin on heterochromatic and euchromatic gene activity in Drosophila melanogaster.

1995 • 74 citations

Distance and pairing effects on the brownDominant heterochromatic element in Drosophila.

1995 • 66 citations

Modification of the Drosophila heterochromatic mutation brownDominant by linkage alterations.

1994 • 63 citations

Transvection at the eyes absent gene of Drosophila.

1994 • 60 citations

MOTTLED WHITE 258–18 OF DROSOPHILA MELANOGASTER

1937 • 58 citations

Do transgene arrays form heterochromatin in vertebrates?

1997 • 58 citations

MIP: An Epigenetic Gene Silencing Process in Ascobolus immersus

1995 • 45 citations

Heterochromatic trans-Inactivation of Drosophila white Transgenes

1997 • 31 citations