Changes in J chain and mu chain RNA expression as a function of B cell differentiation.

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Selected methods in cellular immunology

1981 • 1,915 citations

Methylmercury as a reversible denaturing agent for agarose gel electrophoresis

1976 • 1,323 citations

Identification of a T cell-derived b cell growth factor distinct from interleukin 2.

1982 • 1,095 citations

A plaque assay for all cells secreting Ig of a given type or class

1976 • 1,034 citations

Separation of cells by velocity sedimentation

1969 • 988 citations

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

1978 • 972 citations

Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways

1980 • 880 citations

Two mRNAs with different 3′ ends encode membrane-bound and secreted forms of immunoglobulin μ chain

1980 • 659 citations

[15] Detection of specific RNAs or specific fragments of DNA by fractionation in gels and transfer to diazobenzyloxymethyl paper

1979 • 587 citations

Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends

1980 • 562 citations

Regulation of B-Cell Growth and Differentiation by Soluble Factors

1983 • 432 citations

Messenger RNA for myosin polypeptides: Isolation from single myogenic cell cultures

1977 • 417 citations

Murine B Cell Leukemia Line with Inducible Surface Immunoglobulin Expression

1978 • 388 citations

Membrane Immunoglobulins and Antigen Receptors on B and T Lymphocytes

1974 • 382 citations

Frequency of B lymphocytes responsive to anti-immunoglobulin.

1982 • 302 citations

Immunoglobulin M and Secretory Immunoglobulin A: Presence of a Common Polypeptide Chain Different from Light Chains

1971 • 245 citations

Structure and Function of the J Chain

1975 • 172 citations

Antigen-induced T cell-replacing factor (TRF). III. Establishment of T cell hybrid clone continuously producing TRF and functional analysis of released TRF.

1980 • 166 citations

Characterization of productive and sterile transcripts from the immunoglobulin heavy-chain locus: processing of micron and muS mRNA.

1983 • 165 citations

B cell helper factors. I. Requirement for both interleukin 2 and another 40,000 mol wt factor.

1981 • 159 citations

Mode of regulation of immunoglobulin μ- and δ-chain expression varies during B-lymphocyte maturation

1984 • 146 citations

B Lymphocyte: Activation by Insoluble Anti-Immunoglobulin: Induction of Immunoglobulin Secretion by a T Cell-Dependent Soluble Factor

1979 • 128 citations

Culture supernatants of a stimulated T-cell line have helper activity that acts synergistically with interleukin 2 in the response of B cells to antigen.

1981 • 119 citations

T cell-dependent activation of resting B cells: requirement for both nonspecific unrestricted and antigen-specific Ia-restricted soluble factors.

1981 • 115 citations

Soluble factors involved in B cell differentiation: identification of two distinct T cell-replacing factors (TRF).

1983 • 101 citations

A Third Signal in B Cell Activation Given by TRF

1975 • 95 citations

Triggering mechanism of B lymphocytes. I. Effect of anti-immunoglobulin and enhancing soluble factor on differentiation and proliferation of B cells.

1975 • 90 citations

Separate Signals for the Initiation of Proliferation and Differentiation in the B Cell Response to Antigen

1975 • 74 citations

Expression of J chain RNA in cell lines representing different stages of B lymphocyte differentiation

1981 • 70 citations

B cell differentiation induced by lipopolysaccharide. IV. Development of immunoglobulin class restriction in precursors of IgG-synthesizing cells.

1976 • 63 citations

Characterization of Productive and Sterile Transcripts from the Immunoglobulin Heavy-Chain Locus: Processing of μ_m and μ_s mRNA

1983 • 63 citations

Assembly and secretion of pentameric IgM in a fusion between a nonsecreting B cell lymphoma and an IgG-secreting plasmacytoma.

1979 • 61 citations

Parallel synthesis of immunoglobulins and J chain in pokeweed mitogen-stimulated normal cells and in lymphoblastoid cell lines.

1977 • 61 citations

Primary structure of the immunoglobulin J chain from the mouse.

1982 • 55 citations

Evidence for hydrophobic region within heavy chains of mouse B lymphocyte membrane-bound IgM

1979 • 49 citations

Intracellular Events in the Differentiation of B Lymphocytes to Pentamer IgM Synthesis

1979 • 12 citations