Stable association between the bovine papillomavirus E5 transforming protein and activated platelet-derived growth factor receptor in transformed mouse cells.

Oncogenes and signal transduction

1991 • 2,816 citations

Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 • 653 citations

Association between the PDGF receptor and members of the src family of tyrosine kinases

1990 • 650 citations

Two Different Subunits Associate to Create Isoform-Specific Platelet-derived Growth Factor Receptors

1989 • 633 citations

Polyoma virus transforming protein associates with the product of the c-src cellular gene

1983 • 497 citations

Platelet-derived growth factor: mechanism of action and possible in vivo function.

1990 • 491 citations

Activation of cell growth by binding of Friend spleen focus-forming virus gp55 glycoprotein to the erythropoietin receptor

1990 • 468 citations

Dimerization of B-type Platelet-derived Growth Factor Receptors Occurs After Ligand Binding and Is Closely Associated with Receptor Kinase Activation

1989 • 366 citations

Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation

1984 • 333 citations

Autocrine Stimulation of Intracellular PDGF Receptors in v- sis -Transformed Cells

1988 • 267 citations

Friend spleen focus-forming virus glycoprotein gp55 interacts with the erythropoietin receptor in the endoplasmic reticulum and affects receptor metabolism.

1990 • 244 citations

The E5 Transforming Gene of Bovine Papillomavirus Encodes a Small, Hydrophobic Polypeptide

1986 • 226 citations

Transformation and replication in mouse cells of a bovine papillomavirus--pML2 plasmid vector that can be rescued in bacteria.

1982 • 226 citations

Activation of the platelet-derived growth factor receptor by the bovine papillomavirus E5 transforming protein.

1991 • 224 citations

E5 open reading frame of bovine papillomavirus type 1 encodes a transforming gene

1986 • 206 citations

Ligand-induced dimerization of the platelet-derived growth factor receptor

1989 • 190 citations

Bovine papillomavirus E5 oncoprotein binds to the 16K component of vacuolar H+-ATPases

1991 • 182 citations

The bovine papillomavirus E5 transforming protein can stimulate the transforming activity of EGF and CSF-1 receptors

1989 • 176 citations

Translation of open reading frame E5 of bovine papillomavirus is required for its transforming activity.

1986 • 151 citations

Rapid turnover of the platelet-derived growth factor receptor in sis-transformed cells and reversal by suramin. Implications for the mechanism of autocrine transformation.

1988 • 147 citations

The E5 oncoprotein of bovine papillomavirus is oriented asymmetrically in golgi and plasma membranes

1989 • 133 citations

Tumorigenic transformation of murine keratinocytes by the E5 genes of bovine papillomavirus type 1 and human papillomavirus type 16

1991 • 126 citations

44-amino-acid E5 transforming protein of bovine papillomavirus requires a hydrophobic core and specific carboxyl-terminal amino acids.

1988 • 115 citations

Autocrine mechanism for v-sis transformation requires cell surface localization of internally activated growth factor receptors.

1989 • 112 citations

Genetic and biochemical definition of the bovine papillomavirus E5 transforming protein.

1987 • 92 citations

Activation of erythropoietin receptors by Friend viral gp55 and by erythropoietin and down-modulation by the murine Fv-2r resistance gene.

1990 • 90 citations

The E5 oncoprotein of bovine papillomavirus binds to a 16 kd cellular protein.

1990 • 77 citations

Localization of bovine papillomavirus type 1 E5 protein to transformed basal keratinocytes and permissive differentiated cells in fibropapilloma tissue.

1992 • 71 citations

A glutamine residue in the membrane-associating domain of the bovine papillomavirus type 1 E5 oncoprotein mediates its binding to a transmembrane component of the vacuolar H(+)-ATPase

1992 • 67 citations

Demonstration that a chemically synthesized BPV1 oncoprotein and its C-terminal domain function to induce cellular DNA synthesis

1987 • 56 citations

44-Amino-Acid E5 Transforming Protein of Bovine Papillomavirus Requires a Hydrophobic Core and Specific Carboxyl-Terminal Amino Acids

1988 • 55 citations

Transforming activity of a 16-amino-acid segment of the bovine papillomavirus E5 protein linked to random sequences of hydrophobic amino acids

1989 • 49 citations

The central hydrophobic domain of the bovine papillomavirus E5 transforming protein can be functionally replaced by many hydrophobic amino acid sequences containing a glutamine

1992 • 47 citations

Genetic evidence that acute morphologic transformation, induction of cellular DNA synthesis, and focus formation are mediated by a single activity of the bovine papillomavirus E5 protein.

1989 • 45 citations

The E5 gene of bovine papillomavirus type 1 is sufficient for complete oncogenic transformation of mouse fibroblasts.

1988 • 37 citations