Von Willebrand's disease with spontaneous platelet aggregation induced by an abnormal plasma von Willebrand factor.

A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa.

1983 • 780 citations

Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor

1983 • 469 citations

Platelets have more than one binding site for von Willebrand factor.

1983 • 459 citations

Heightened Interaction between Platelets and Factor VIII/von Willebrand Factor in a New Subtype of von Willebrand's Disease

1980 • 381 citations

[67] Thiobarbituric acid assay of sialic acids

1963 • 265 citations

Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated platelets.

1982 • 261 citations

Platelet Aggregation Induced by I-Desamino-8-D-Arginine Vasopressin (dDAVP) in Type IIb von Willebrand's Disease

1983 • 260 citations

Evidence that three adhesive proteins interact with a common recognition site on activated platelets.

1984 • 254 citations

Factor VIII-related protein circulates in normal human plasma as high molecular weight multimers

1980 • 238 citations

Pseudo-von Willebrand's Disease

1982 • 219 citations

Platelet-type von Willebrand's disease: characterization of a new bleeding disorder

1982 • 197 citations

Prostacyclin inhibits mobilisation of fibrinogen-binding sites on human ADP- and thrombin-treated platelets

1980 • 193 citations

Thrombin-induced exposure and prostacyclin inhibition of the receptor for factor VIII/von Willebrand factor on human platelets.

1982 • 190 citations

Enzymic methods for the micro assay of D-mannose, D-glucose, D-galactose, and L-fucose from acid hydrolyzates of glycoproteins

1969 • 152 citations

Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregation.

1985 • 150 citations

Heterogeneity of human whole blood platelet subpopulations. II. Use of a subhuman primate model to analyze the relationship between density and platelet age

1978 • 148 citations

Properties of human asialo-factor VIII. A ristocetin-independent platelet-aggregating agent.

1981 • 126 citations

Fibrinogen competes with von Willebrand factor for binding to the glycoprotein IIb/IIIa complex when platelets are stimulated with thrombin

1984 • 119 citations

Effect of multimeric structure of the factor VIII/von Willebrand factor protein on binding to platelets

1981 • 115 citations

von Willebrand factor binds to platelets and induces aggregation in platelet-type but not type IIB von Willebrand disease.

1983 • 103 citations

Interaction of von Willebrand factor with human platelets in the plasma milieu.

1984 • 95 citations

Asialo von Willebrand factor interactions with platelets. Interdependence of glycoproteins Ib and IIb/IIIa for binding and aggregation.

1985 • 93 citations

Studies of the human factor VIII/von Willebrand factor protein. III. Qualitative defects in von Willebrand's disease.

1975 • 93 citations

Inhibition of von Willebrand factor–platelet interaction by fibrinogen

1984 • 72 citations

Evidence that changes in platelet cyclic AMP levels regulate the fibrinogen receptor on human platelets.

1982 • 70 citations

Aggregation of Human Platelets by Bovine or Human Factor VIII: Role of Carbohydrate Side Chains

1973 • 68 citations

Studies with a murine monoclonal antibody that abolishes ristocetin- induced binding of von Willebrand factor to platelets: additional evidence in support of GPIb as a platelet receptor for von Willebrand factor

1983 • 62 citations

Studies on the pathophysiology and treatment of von willebrand's disease. IV. Mechanism of increased ristocetin-induced platelet aggregation in von willebrand's disease

1980 • 45 citations

Inhibition of von Willebrand factor-dependent platelet function by increased platelet cyclic AMP and its prevention by cytoskeleton- disrupting agents

1981 • 35 citations

Characterization of the defect of the factor VIII/von Willebrand factor protein in von Willebrand's disease

1982 • 34 citations

Further characterization of platelet-type von Willebrand's disease in Japan

1984 • 32 citations

Von willebrand disease with an increased ristocetin‐induced platelet aggregation and a qualitative abnormality of the factor VIII protein

1980 • 32 citations

Platelet‐Aggregating Activity in Neuraminidase‐Treated Human Cryoprecipitates: Its Correlation with Factor‐VIII‐Related Antigen

1974 • 26 citations

Factor VIII and Human Platelet Aggregation

1976 • 24 citations

In vivo interaction of von Willebrand factor with platelets following cryoprecipitate transfusion in platelet-type von Willebrand's disease

1984 • 19 citations

In vivo interaction of von Willebrand factor with platelets following cryoprecipitate transfusion in platelet-type von Willebrand's disease

1984 • 18 citations

Differentiation of patients with subtype IIb‐like von Willebrand's disease by means of perfusion experiments with reconstituted blood

1985 • 17 citations

Factor VIII-related protein circulates in normal human plasma as high molecular weight multimers

1980 • 14 citations

Factor VIII and Human Platelet Aggregation

1976 • 12 citations

Effect of multimeric structure of the factor VIII/von Willebrand factor protein on binding to platelets

1981 • 11 citations

Inhibition of von Willebrand factor-dependent platelet function by increased platelet cyclic AMP and its prevention by cytoskeleton- disrupting agents

1981 • 3 citations

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