Gene elimination in carcinogenesis: reinterpretation of the somatic mutation theory.

Carcinogenic Nitroso Compounds

1967 • 1,109 citations

Evidence for the Binding of Polynuclear Aromatic Hydrocarbons to the Nucleic Acids of Mouse Skin : Relation between Carcinogenic Power of Hydrocarbons and their Binding to Deoxyribonucleic Acid

1964 • 687 citations

Mechanisms of chemical carcinogenesis: nature of proximate carcinogens and interactions with macromolecules.

1966 • 489 citations

Effects of Some Chemical Mutagens and Carcinogens on Nucleic Acids

1966 • 370 citations

8-(N-2-Fluorenylacetamido) guanosine, an Arylamidation Reaction Product of Guanosine and the Carcinogen N-Acetoxy-N-2-fluorenylacetamide in Neutral Solution^*

1967 • 335 citations

Localization and Function of Heterochromatin in Drosophila Melanogaster

1951 • 178 citations

Nucleic Acid Guanine: Reaction with the Carcinogen N -Acetoxy-2-Acetylaminofluorene

1966 • 151 citations

The Interaction of Polycyclic Hydrocarbons and Nucleic Acids

1962 • 143 citations

The significance of mutation in relation to the origin of tumors: a review.

1955 • 129 citations

Mutations and decreases in density of transforming DNA produced by derivatives of the carcinogens 2-acetyl-aminofluorene and N-methyl-4-aminoazobenzene.

1968 • 118 citations

Binding of tritium-labeled polycyclic hydrocarbons to DNA of mouse skin.

1967 • 118 citations

Bioassay of 29 Alkylatlng Chemicals by the Pulmonary-Tumor Response In Strain A Mice

1966 • 117 citations

Interaction between DNA and polycyclic aromatic hydrocarbons

1962 • 95 citations

Further experimental studies on the inheritance of susceptibility to a Transplantable tumor, Carcinoma (J. W. A.) of the Japanese waltzing Mouse.

1916 • 95 citations

Cytogenetic analysis of the action of carcinogens and tumour inhibitors indrosophila melanogaster

1954 • 65 citations

COMPARATIVE MUTAGENESIS OF THE DUMPY LOCUS IN DROSOPHILA MELANOGASTER. II. MUTATIONAL MOSAICISM INDUCED WITHOUT APPARENT BREAKAGE BY A MONOFUNCTIONAL ALKYLATING AGENT

1962 • 65 citations

Cytogenetic analysis of the action of carcinogens and tumour inhibitors inDrosophila melanogasterI. 1:2, 3:4-diepoxybutane

1953 • 51 citations

The binding of metabolites of aminoazo dyes to rat liver DNA in vivo.

1967 • 49 citations

Differential mutagenicity of the amine and amide derivatives of nitroso compounds in Drosophila melanogaster

1966 • 47 citations

The interaction of carcinogenic hydrocarbons with tissue constituents. II. 1,2,5,6-Dibenzanthracene-9,10-C14 in skin.

1953 • 45 citations

Studies on the Structure of the Skin Protein-bound Compounds Following Topical Application of 1,2,5,6-Dibenzanthracene-9,10-C¹⁴. I. 2-Phenylphenanthrene-3,2'-dicarboxylic Acid, a Degradation Product^1,2

1955 • 40 citations

Cytogenetic analysis of the action of carcinogens and tumour inhibitors inDrosophila melanogaster iv. The cell stage during spermatogenesis and the induction of intra and inter-genic mutations by 2:4:6-tri(ethyleneimino)-1: 3:5-triazine

1955 • 39 citations

Pulmonary-tumor induction in mice with chemical agents used in the clinical management of lymphomas

1954 • 38 citations

Induction of Mutations by Deoxyribonucleic Acid in Drosophila Melanogaster

1961 • 33 citations

CYTOGENETIC ANALYSIS OF THE ACTION OF CARCINOGENS AND TUMOUR INHIBITORS IN DROSOPHILA MELANOGASTER. XI. MUTAGENIC EFFICIENCY OF THE MESYLOXY ESTERS ON THE SPERM IN RELATION TO MOLECULAR STRUCTURE

1961 • 32 citations

Chemische Konstitution und mutagene Wirkung

1968 • 29 citations

The mutagenic properties of the nucleosides of pyrimidine analogues in Drosophila melanogaster

1966 • 26 citations

CYTOGENETIC ANALYSIS OF THE ACTION OF CARCINOGENS AND TUMOR INHIBITORS IN DROSOPHILA MELANOGASTER. VIII. SELECTIVE MUTAGENIC ACTIVITY OF S-2-CHLOROETHYLCYSTEINE ON THE SPERMATOGONIAL STAGES

1960 • 25 citations

Mutagenic Activity of Cellular Macromolecules in Drosophila Melanogaster

1962 • 24 citations

Mutagenicity in the sperm of Drosophila and the structure of the “nitrogen-mustard” molecule

1960 • 22 citations

DIFFERENTIAL INDUCTION OF CHROMOSOME DELETIONS BY NATURAL AND SYNTHETIC MACROMOLECULES IN DROSOPHILA MELANOGASTER

1965 • 14 citations

THE NATURE AND DISTRIBUTION OF THE MUTATIONS INDUCED BY UNIRRADIATED AND IRRADIATED HETEROLOGOUS DEOXYRIBONUCLEIC ACID IN DROSOPHILA MELANOGASTER

1966 • 13 citations

Mutagenicity of Ionic Polymers and LeukÆmogenic Viruses Relative to Nucleic Acids in Drosophila melanogaster

1964 • 9 citations

STUDIES ON THE MOLECULAR AND CELLULAR MECHANISMS OF HYDROCARBON CARCINOGENESIS

1966 • 7 citations