Positive Cooperativity of Acetylcholine and Other Agonists with Allosteric Ligands on Muscarinic Acetylcholine Receptors

Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells.

1989 • 627 citations

Estimation of the affinities of allosteric ligands using radioligand binding and pharmacological null methods.

1988 • 335 citations

Modification of the binding properties of muscarinic receptors by gallamine.

1983 • 321 citations

Detection, quantitation, and verification of allosteric interactions of agents with labeled and unlabeled ligands at G protein-coupled receptors: interactions of strychnine and acetylcholine at muscarinic receptors.

1995 • 259 citations

THE INHIBITORY EFFECT OF GALLAMINE ON MUSCARINIC RECEPTORS

1976 • 249 citations

Xanomeline: a novel muscarinic receptor agonist with functional selectivity for M1 receptors.

1994 • 165 citations

Allosteric modulation of muscarinic acetylcholine receptors

1995 • 155 citations

Novel functional M1 selective muscarinic agonists. Synthesis and structure-activity relationships of 3-(1,2,5-thiadiazolyl)-1,2,5,6-tetrahydro-1-methylpyridines

1992 • 151 citations

Activation of muscarinic acetylcholine receptors via their allosteric binding sites.

1996 • 109 citations

Allosteric antagonists of the muscarinic acetylcholine receptor

1991 • 102 citations

Mechanisms of steric and cooperative actions of alcuronium on cardiac muscarinic acetylcholine receptors.

1994 • 91 citations

Ligand binding properties of muscarinic acetylcholine receptor subtypes (m1-m5) expressed in baculovirus-infected insect cells.

1995 • 77 citations

Subtype selectivity of the positive allosteric action of alcuronium at cloned M1-M5 muscarinic acetylcholine receptors.

1995 • 72 citations

Positive cooperativity in the binding of alcuronium and N-methylscopolamine to muscarinic acetylcholine receptors.

1990 • 70 citations

Neurochemical effects of the M1 muscarinic agonist xanomeline (LY246708/NNC11-0232).

1994 • 60 citations

‘Inverse agonists’, cooperativity and drug action at benzodiazepine receptors

1986 • 52 citations

Interaction of the neuromuscular blocking drugs alcuronium, decamethonium, gallamine, pancuronium, ritebronium, tercuronium and d-tubocurarine with muscarinic acetylcholine receptors in the heart and ileum

1985 • 45 citations

Competition between positive and negative allosteric effectors on muscarinic receptors.

1995 • 42 citations

Positive and negative allosteric interactions on muscarinic receptors

1995 • 38 citations

Allosteric regulation of G-protein-linked receptors

1995 • 32 citations

Assessment of the allosteric interactions of the bisquaternary heptane-1,7-bis(dimethyl-3'-phthalimidopropyl)ammonium bromide at M1 and M2 muscarine receptors.

1994 • 31 citations

Protection by Alcuronium of Muscarinic Receptors Against Chemical Inactivation and Location of the Allosteric Binding Site for Alcuronium

1994 • 29 citations

Two populations of muscarinic binding sites in the chick heart distinguished by affinities for ligands and selective inactivation

1994 • 25 citations

Allosteric Interactions of Muscarinic Receptors and Their Regulation by Other Membrane Proteins

1989 • 21 citations

Positive allosteric action of eburnamonine on cardiac muscarinic acetylcholine receptors

1996 • 18 citations

Antimuscarinic and Ganglion-Blocking Activity of Neuromuscular Blocking Agents

1986 • 13 citations

Allosteric interactions between alcuronium and ligands binding to the classical binding site on cardiac muscarinic receptors

1995 • 7 citations

<b>ALLOSTERIC BINDING OF 9-METHOXY-ALPHA-LAPACHONE AND ALCURONIUM TO THE MUSCARINIC ACETYLCHOLINE RECEPTOR m2 </b><b>SUBTYPE </b>

1995 • 5 citations