The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A

1993 • 1,941 citations

Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC

1993 • 1,273 citations

A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma

1994 • 1,140 citations

Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC

1994 • 646 citations

Single missense mutation in the tyrosine kinasecatalytic domain of the RET protooncogene is associated with multiple endocrineneoplasia type 2B.

1994 • 591 citations

Point mutation within the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours

1994 • 531 citations

Clinical Screening as Compared with DNA Analysis in Families with Multiple Endocrine Neoplasia Type 2A

1994 • 453 citations

Diversity of RET proto-oncogene mutations in familial and sporadic Hirschsprung disease

1995 • 311 citations

Familial medullary thyroid carcinoma without associated endocrinopathies: A distinct clinical entity

1986 • 307 citations

Syndrome of Bilateral Pheochromocytoma, Medullary Thyroid Carcinoma and Multiple Neuromas

1968 • 298 citations

Embryogenesis of intramural ganglia of the gut and its relation to Hirschsprung's disease

1967 • 281 citations

Genotype‐phenotype correlation in multiple endocrine neoplasia type 2: report of the International RET Mutation Consortium

1995 • 272 citations

A novel point mutation in the tyrosine kinase domain of the RET proto-oncogene in sporadic medullary thyroid carcinoma and in a family with FMTC.

1995 • 253 citations

Diverse phenotypes associated with exon 10 mutations of the RET proto-oncogene

1994 • 246 citations

Mutation analysis of the RET receptor tyrosine kinase in Hirschsprung disease

1995 • 243 citations

RET mutations in exons 13 and 14 of FMTC patients.

1995 • 220 citations

Multiple Endocrine Neoplasia Type 2a Associated with Cutaneous Lichen Amyloidosis

1989 • 216 citations

Low frequency of germline mutations in the RET proto‐oncogene in patients with apparently sporadic medullary thyroid carcinoma

1995 • 175 citations

Analysis ofRET protooncogene point mutations distinguishes heritable from nonheritable medullary thyroid carcinomas

1995 • 136 citations

Mutations of codon 918 in the RET proto-oncogene correlate to poor prognosis in sporadic medullary thyroid carcinomas.

1995 • 134 citations

RET proto-oncogene mutations in French MEN 2A and FMTC families

1994 • 128 citations

Hirschsprungʼs Disease in a Family with Multiple Endocrine Neoplasia Type 2

1982 • 126 citations

Cost comparison of molecular versus conventional screening of relatives at risk for retinoblastoma.

1996 • 101 citations

Mutational analysis of multiple endocrine neoplasia type 2A associated with Hirschsprung's disease

1995 • 99 citations

Genetic Aspects of Multiple Endocrine Neoplasia

1984 • 95 citations

RET proto-oncogene point mutations in sporadic neuroendocrine tumors.

1996 • 81 citations

The identification of false positive responses to the pentagastrin stimulation test in RET mutation negative members of MEN 2A families

1996 • 75 citations

Role of the RET proto-oncogene in sporadic hyperparathyroidism and in hyperparathyroidism of multiple endocrine neoplasia type 2.

1996 • 71 citations

10 Multiple endocrine neoplasia

1988 • 54 citations

Family Screening in Medullary Thyroid Carcinoma Presenting Without a Family History

1988 • 32 citations

Haplotype analysis of MEN 2 mutations

1994 • 24 citations

Unusual features of multiple endocrine neoplasia.

1992 • 17 citations

RET mutations in MEN 2 associated diseases

1994 • 8 citations

Of double stomachs

1975 • 2 citations