Sensitive detection of RNAs in single cells by flow cytometry

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

1986 • 3,231 citations

High-Resolution Mapping of Human Chromosome 11 by in Situ Hybridization with Cosmid Clones

1990 • 1,357 citations

Intracellular localization of messenger RNAs for cytoskeletal proteins

1986 • 639 citations

Sensitive, high-resolution chromatin and chromosome mapping in situ: Presence and orientation of two closely integrated copies of EBV in a lymphoma line

1988 • 550 citations

Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle.

1983 • 452 citations

Highly localized tracks of specific transcripts within interphase nuclei visualized by in situ hybridization

1989 • 434 citations

THE CYTOPLASMIC SYNTHESIS OF HISTONES IN HELA CELLS AND ITS TEMPORAL RELATIONSHIP TO DNA REPLICATION

1967 • 421 citations

Separation of basal histone synthesis from S-phase histone synthesis in dividing cells

1981 • 352 citations

The synthesis of oligonucleotides containing an aliphatic amino group at the 5′ terminus: synthesis of fluorescent DNA primers for use in DNA sequence analysis

1985 • 334 citations

Coordinate regulation of multiple histone mRNAs during the cell cycle in HeLa cells

1983 • 278 citations

The proximity of DNA sequences in interphase cell nuclei is correlated to genomic distance and permits ordering of cosmids spanning 250 kilobase pairs

1989 • 230 citations

Regulation of Human Histone Gene Expression: Kinetics of Accumulation and Changes in the Rate of Synthesis and in the Half-Lives of Individual Histone mRNAs During the HeLa Cell Cycle

1983 • 218 citations

Mapping of single-copy DNA sequences on human chromosomes by in situ hybridization with biotinylated probes: enhancement of detection sensitivity by intensified-fluorescence digital-imaging microscopy.

1989 • 138 citations

Five-parameter fluorescence imaging: wound healing of living Swiss 3T3 cells.

1987 • 127 citations

Regulation of human histone gene expression: transcriptional and posttranscriptional control in the coupling of histone messenger RNA stability with DNA replication

1987 • 111 citations

Direct visualization of single copy genes on banded metaphase chromosomes by nonisotopicin situhybridization

1988 • 110 citations

Sensitive and high resolution in situ hybridization to human chromosomes using biotin labelled probes: assignment of the human thymocyte CD1 antigen genes to chromosome 1.

1988 • 96 citations

Fluorescence in situ hybridization to interphase cell nuclei in suspension allows flow cytometric analysis of chromosome content and microscopic analysis of nuclear organization

1988 • 95 citations

Detection of DNA Sequences in Nuclei in Suspension by in Situ Hybridization and Dual Beam Flow Cytometry

1985 • 92 citations

Analysis of histone gene expression during the cell cycle in HeLa cells by using cloned human histone genes.

1982 • 83 citations

Reassessment of histone gene expression during cell cycle in human cells by using homologous H4 histone cDNA.

1979 • 66 citations

Flow cytometric detection of ribosomal RNA in suspended cells by fluorescent in situ hybridization

1988 • 58 citations

Cytochemical hybridization with fluorochrome-labeled RNA. II. Applications.

1981 • 51 citations

Comparison of 35S and biotin as labels for in situ hybridization: use of an HPV model system.

1991 • 49 citations

A method for nucleic acid hybridization to isolated chromosomes in suspension

1987 • 45 citations

Flow cytometric detection of β-globin mRNA in murine haemopoietic tissues using fluorescent in situ hybridization

1990 • 25 citations