Differences in Glucose Transporter Gene Expression between Rat Pancreatic α- and β-Cells Are Correlated to Differences in Glucose Transport but Not in Glucose Utilization

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Sequence and Structure of a Human Glucose Transporter

1985 • 1,557 citations

Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and β-pancreatic islet cells

1988 • 786 citations

Developmental Expression of PDGF, TGF-α, and TGF-β Genes in Preimplantation Mouse Embryos

1988 • 688 citations

Pancreatic islet glucose metabolism and regulation of insulin secretion

1986 • 506 citations

A New in Vitro Model for the Study of Pancreatic A and B Cells*

1985 • 345 citations

Generation of cDNA Probes Directed by Amino Acid Sequence: Cloning of Urate Oxidase

1988 • 325 citations

Family of Glucose-Transporter Genes: Implications for Glucose Homeostasis and Diabetes

1990 • 310 citations

Expression of human glucose transporters in Xenopus oocytes: kinetic characterization and substrate specificities of the erythrocyte, liver, and brain isoforms

1991 • 298 citations

Glucokinase as pancreatic beta cell glucose sensor and diabetes gene.

1993 • 281 citations

Diabetic Hyperglycemia: Link to Impaired Glucose Transport in Pancreatic β Cells

1991 • 260 citations

Characterization of the Effects of Arginine and Glucose on Glucagon and Insulin Release from the Perfused Rat Pancreas

1974 • 231 citations

Glucose sensing in pancreatic islet beta cells: the key role of glucokinase and the glycolytic intermediates.

1993 • 209 citations

The high Km glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence.

1990 • 204 citations

Heterogeneity in Pancreatic β-cell Population

1992 • 198 citations

Localization of the Pancreatic Beta Cell Glucose Transporter to Specific Plasma Membrane Domains

1989 • 195 citations

The ubiquitous glucose transporter GLUT-1 belongs to the glucose-regulated protein family of stress-inducible proteins.

1991 • 172 citations

Heterogeneity in glucose sensitivity among pancreatic beta-cells is correlated to differences in glucose phosphorylation rather than glucose transport.

1993 • 168 citations

Interplay of Nutrients and Hormones in the Regulation of Glucagon Release*

1985 • 162 citations

Transfection of AtT-20ins cells with GLUT-2 but not GLUT-1 confers glucose-stimulated insulin secretion. Relationship to glucose metabolism

1993 • 154 citations

Elusive Proximal Signals of β-Cells for Insulin Secretion

1990 • 151 citations

Glucose deprivation and hexose transporter polypeptides of murine fibroblasts.

1986 • 149 citations

Molecular and Cellular Physiology of GLUT-2, a High-KmFacilitated Diffusion Glucose Transporter

1992 • 125 citations

Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion.

1994 • 125 citations

Regulation of beta-cell glucose transporter gene expression.

1990 • 107 citations

Effect of nutrients, hormones and serum on survival of rat islet beta cells in culture

1994 • 105 citations

Intra-islet insulin permits glucose to directly suppress pancreatic A cell function.

1991 • 103 citations

Differences in glucose handling by pancreatic A- and B-cells.

1984 • 91 citations

Expression of yeast hexokinase in pancreatic beta cells of transgenic mice reduces blood glucose, enhances insulin secretion, and decreases diabetes.

1992 • 75 citations

Expression and function of GLUT-1 and GLUT-2 glucose transporter isoforms in cells of cultured rat pancreatic islets.

1992 • 73 citations

Glucokinase and candidate genes for Type 2 (non-insulin-dependent) diabetes mellitus

1993 • 71 citations

Replacement of intracellular C-terminal domain of GLUT1 glucose transporter with that of GLUT2 increases Vmax and Km of transport activity.

1992 • 61 citations

GLUT2 surface expression and intracellular transport via the constitutive pathway in pancreatic beta cells and insulinoma: evidence for a block in trans-Golgi network exit by brefeldin A.

1993 • 41 citations

Glucose Transporter Isotypes Switch in T-Antigen-Transformed Pancreatic β Cells Growing in Culture and in Mice

1992 • 34 citations