Repair of Large Insertion/Deletion Heterologies in Human Nuclear Extracts Is Directed by a 5′ Single-strand Break and Is Independent of the Mismatch Repair System

Genomic sequencing.

1984 • 8,343 citations

de la Chapelle, A.

1997 • 3,184 citations

Mutation of a mutL Homolog in Hereditary Colon Cancer

1994 • 1,834 citations

MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY

1996 • 1,485 citations

Frameshift Mutations and the Genetic Code

1966 • 1,400 citations

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1993 • 1,042 citations

MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH REPAIR

1991 • 876 citations

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

1995 • 599 citations

Biochemistry and genetics of eukaryotic mismatch repair.

1996 • 598 citations

DNA Mismatch Correction in a Defined System

1989 • 551 citations

Mutations of GTBP in Genetically Unstable Cells

1995 • 471 citations

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.

1990 • 408 citations

Isolation of MutSβ from Human Cells and Comparison of the Mismatch Repair Specificities of MutSβ and MutSα

1998 • 405 citations

Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.

1995 • 403 citations

Genetic recombination

1989 • 373 citations

Heteroduplex repair in extracts of human HeLa cells

1991 • 355 citations

Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions.

1992 • 353 citations

Mispair specificity of methyl-directed DNA mismatch correction in vitro.

1988 • 341 citations

Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability.

1994 • 332 citations

Replication of Eukaryotic Chromosomes: A Close-up of the Replication Fork

1980 • 330 citations

EFFECTS OF HIGH LEVELS OF DNA ADENINE METHYLATION ON METHYL-DIRECTED MISMATCH REPAIR IN ESCHERICHIA COLI

1983 • 294 citations

Heteroduplex deoxyribonucleic acid base mismatch repair in bacteria

1986 • 252 citations

FRAMESHIFT MUTATION: DETERMINANTS OF SPECIFICITY

1990 • 238 citations

DNA Polymerase δ Is Required for Human Mismatch Repair in Vitro

1997 • 227 citations

Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction

1993 • 224 citations

Repair of DNA heteroduplexes containing small heterologous sequences in Escherichia coli.

1992 • 215 citations

Involvement of DNA polymerase alpha in simian virus 40 DNA replication.

1978 • 214 citations

Repair of DNA loops involves DNA-mismatch and nucleotide-excision repair proteins

1997 • 146 citations

DNA Loop Repair by Human Cell Extracts

1994 • 125 citations

The Recombination of Genetic Material

1988 • 116 citations

Requirement for d(GATC) sequences in Escherichia coli mutHLS mismatch correction.

1987 • 109 citations

Detection of heteroduplex DNA molecules among the products of Saccharomyces cerevisiae meiosis.

1990 • 107 citations

A Naturally Occurring hPMS2 Mutation Can Confer a Dominant Negative Mutator Phenotype

1998 • 98 citations

A hPMS2 Mutant Cell Line Is Defective in Strand-specific Mismatch Repair

1995 • 89 citations

Role of DNA polymerase γ in adenovirus DNA replication

1978 • 66 citations

Repair of heteroduplex DNA molecules with multibase loops in Escherichia coli

1993 • 51 citations

Repair of single-stranded loops in heteroduplex DNA transfected into mammalian cells.

1987 • 47 citations

Single gene complementation of the hPMS2 defect in HEC-1-A endometrial carcinoma cells.

1998 • 42 citations

Repair of single-stranded DNA nicks, gaps, and loops in mammalian cells.

1987 • 41 citations

Large non-homology in heteroduplex DNA is processed differently than single base pair mismatches

1987 • 32 citations

Methyl-directed Repair of Mismatched Small Heterologous Sequences in Cell Extracts from Escherichia coli

1997 • 29 citations

Heteroduplex-induced mutagenesis in mammalian cells

1988 • 14 citations

Effects of nicks on repair of single-stranded loops in heteroduplex DNA in mammalian cells

1989 • 11 citations