Structural bases of vasopressin/oxytocin receptor function

MODEL SYSTEMS FOR THE STUDY OF SEVEN-TRANSMEMBRANE-SEGMENT RECEPTORS

1991 • 1,357 citations

Structure and expression of a human oxytocin receptor

1992 • 622 citations

Palmitoylation of the human β2-adrenergic receptor

1989 • 599 citations

Molecular cloning of the receptor for human antidiuretic hormone

1992 • 529 citations

Molecular Biology of Muscarinic Acetylcholine Receptors

1996 • 488 citations

In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptors

1992 • 470 citations

Hormonal Stimulation of Phosphatidylinositol Breakdown, with Particular Reference to the Hepatic Effects of Vasopressin

1979 • 431 citations

Two adjacent cysteine residues in the C‐terminal cytoplasmic fragment of bovine rhodopsin are palmitylated

1988 • 409 citations

Vasopressin and Oxytocin Receptors in the Central Nervous System

1996 • 402 citations

Molecular cloning and functional expression of a cDNA encoding the human V1b vasopressin receptor.

1994 • 368 citations

The role of adenosine 3′,5′-phosphate in the action of antidiuretic hormone

1967 • 349 citations

Extrapituitary expression of the rat V1b vasopressin receptor gene.

1995 • 332 citations

Molecular cloning, sequencing, and functional expression of a cDNA encoding the human V1a vasopressin receptor.

1994 • 281 citations

The Binding Site of Neuropeptide Vasopressin V1a Receptor

1995 • 254 citations

Cloning and characterization of the human V3 pituitary vasopressin receptor

1994 • 202 citations

Nephrogenic diabetes insipidus. A V2 vasopressin receptor unable to stimulate adenylyl cyclase

1993 • 185 citations

Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor.

1995 • 174 citations

Functional role of proline and tryptophan residues highly conserved among G protein-coupled receptors studied by mutational analysis of the m3 muscarinic receptor.

1993 • 165 citations

Carbachol and oxytocin stimulate the generation of inositol phosphates in the guinea pig myometrium

1986 • 159 citations

X-linked nephrogenic diabetes insipidus mutations in North America and the Hopewell hypothesis.

1993 • 149 citations

Separate Agonist and Peptide Antagonist Binding Sites of the Oxytocin Receptor Defined by Their Transfer into the V2 Vasopressin Receptor

1996 • 131 citations

Different Single Receptor Domains Determine the Distinct G Protein Coupling Profiles of Members of the Vasopressin Receptor Family

1996 • 129 citations

Functional studies of twelve mutant V2 vasopressin receptors related to nephrogenic diabetes insipidus

1998 • 110 citations

Two aromatic residues regulate the response of the human oxytocin receptor to the partial agonist arginine vasopressin

1996 • 109 citations

Design, Synthesis and Some uses of Receptor-Specific Agonists and Antagonists of Vasopressin and Oxytocin

1993 • 93 citations

A fully active nonglycosylated V2 vasopressin receptor.

1996 • 82 citations

Molecular and functional characterization of V1b vasopressin receptor in rat adrenal medulla.

1996 • 81 citations

Direct identification of an extracellular agonist binding site in the renal V2 vasopressin receptor

1993 • 78 citations

Molecular characterization of a cloned human oxytocin receptor

1994 • 76 citations

Palmitoylation of the V₂Vasopressin Receptor

1997 • 74 citations

An extracellular congenital nephrogenic diabetes insipidus mutation of the vasopressin receptor reduces cell surface expression, affinity for ligand, and coupling to the Gs/adenylyl cyclase system.

1994 • 73 citations

The cloned vasopressin V1a receptor stimulates phospholipase A2, phospholipase C, and phospholipase D through activation of receptor-operated calcium channels

1994 • 68 citations

An extracellular residue determines the agonist specificity of V₂ vasopressin receptors

1995 • 64 citations

Mapping Peptide-binding Domains of the Human V1a Vasopressin Receptor with a Photoactivatable Linear Peptide Antagonist

1997 • 61 citations

Model Systems For The Study Of Seven-Transmembrane-Segment Receptors

1991 • 60 citations

Effects of oxytocin on ionic currents underlying rhythmic activity and contraction in uterine smooth muscle

1976 • 55 citations

Small molecule ligands for oxytocin and vasopressin receptors

1997 • 50 citations

Mutational analysis and molecular modeling of the nonapeptide hormone binding domains of the [Arg8]vasotocin receptor.

1996 • 45 citations

Molecular and functional characterization of V1b vasopressin receptor in rat adrenal medulla

1996 • 36 citations

Molecular recognition of peptide and non-peptide ligands by the extracellular domains of neurohypophysial hormone receptors

1996 • 35 citations

An extracellular congenital nephrogenic diabetes insipidus mutation of the vasopressin receptor reduces cell surface expression, affinity for ligand, and coupling to the Gs/adenylyl cyclase system

1994 • 29 citations

G protein coupling of human platelet V1 vascular vasopressin receptors

1993 • 26 citations

Hepatic Vasopressin Receptor: Differential Effects of Divalent Cations, Guanine Nucleotides, andN-Ethylmaleimide on Agonist and Antagonist Interactions with the V₁Subtype Receptor*

1988 • 25 citations

Three Novel AVPR2 Mutations in Three Japanese Families with X-Linked Nephrogenic Diabetes Insipidus

1996 • 24 citations

A New Series of Photoactivatable and Iodinatable Linear Vasopressin Antagonists

1994 • 23 citations

Differential inactivation of vasopressin receptor subtypes in isolated membranes and intact cells by N‐ethylmaleimide

1990 • 20 citations

Towards understanding the role of the first extracellular loop for the binding of peptide hormones to G-protein coupled receptors

1995 • 17 citations

N-glycosylation plays a role in biosynthesis and internalization of the adenylate cyclase stimulating vasopressin V2-receptor of LLC-PK1 renal epithelial cells: An effect of concanavalin A on binding and expression

1992 • 15 citations

Efficient Photoaffinity Labeling of the Rat V_1a, Vasopressin Receptor using a Linear Azidopeptidic Antagonist

1997 • 14 citations

Synthetic Rat V1a Vasopressin Receptor Fragments Interfere with Vasopressin Binding via Specific Interaction with the Receptor

1997 • 11 citations