Reciprocal Rb inactivation and p16INK4 expression in primary lung cancers and cell lines.

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1993 • 3,680 citations

A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types

1994 • 2,821 citations

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

1994 • 1,806 citations

A novel cyclin encoded by a bcl1-linked candidate oncogene

1991 • 1,286 citations

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

1993 • 1,258 citations

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

1994 • 1,142 citations

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

1993 • 1,047 citations

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

1992 • 1,023 citations

Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining.

1994 • 673 citations

Amplification and expression of the human cyclin D gene in esophageal cancer.

1992 • 411 citations

Cyclin E, a Potential Prognostic Marker in Breast Cancer.

1997 • 346 citations

Frequent somatic mutation of the MTS1/CDK4I (multiple tumor suppressor/cyclin-dependent kinase 4 inhibitor) gene in esophageal squamous cell carcinoma.

1994 • 345 citations

The Human Homolog of the JE Gene Encodes a Monocyte Secretory Protein

1989 • 227 citations

The Molecular Biology of Lung Cancer Pathogenesis

1993 • 116 citations

Amplification and expression of the bcl-1 gene in human solid tumor cell lines.

1992 • 45 citations