Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts

Molecular portraits of human breast tumours

2000 • 15,445 citations

Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer

2013 • 12,861 citations

Gene expression profiling predicts clinical outcome of breast cancer

2002 • 9,314 citations

A Gene-Expression Signature as a Predictor of Survival in Breast Cancer

2002 • 6,428 citations

pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long‐term follow‐up

1991 • 5,979 citations

Ki67 expression in breast cancer

2016 • 4,269 citations

Tamoxifen for early breast cancer: an overview of the randomised trials

1998 • 4,082 citations

A molecular signature of metastasis in primary solid tumors

2002 • 2,424 citations

Polychemotherapy for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group.

1998 • 2,199 citations

Polychemotherapy for early breast cancer: an overview of the randomised trials

1998 • 2,023 citations

Breast cancer classification and prognosis based on gene expression profiles from a population-based study

2003 • 2,013 citations

Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial

2002 • 1,954 citations

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

1998 • 1,850 citations

A Randomized Trial of Exemestane after Two to Three Years of Tamoxifen Therapy in Postmenopausal Women with Primary Breast Cancer

2004 • 1,746 citations

Pathological prognostic factors in breast cancer

1999 • 1,676 citations

Randomized Trial of Dose-Dense Versus Conventionally Scheduled and Sequential Versus Concurrent Combination Chemotherapy as Postoperative Adjuvant Treatment of Node-Positive Primary Breast Cancer: First Report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741

2003 • 1,525 citations

Distinctive gene expression patterns in human mammary epithelial cells and breast cancers

1999 • 1,410 citations

Cancer—Principles & Practice of Oncology

1983 • 1,403 citations

National Institutes of Health Consensus Development Conference Statement: Geriatric Assessment Methods for Clinical Decision‐making

1988 • 1,353 citations

Improved Outcomes From Adding Sequential Paclitaxel but Not From Escalating Doxorubicin Dose in an Adjuvant Chemotherapy Regimen for Patients With Node-Positive Primary Breast Cancer

2003 • 1,286 citations

Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: an overview of the randomised trials

2000 • 1,127 citations

Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression

2004 • 1,025 citations

Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer

2003 • 889 citations

National Institutes of Health Consensus Development Conference Statement: Adjuvant Therapy for Breast Cancer, November 1-3, 2000

2001 • 888 citations

Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: an overview of the randomised trials

2000 • 833 citations

A prediction-based resampling method for estimating the number of clusters in a dataset

2002 • 694 citations

erbB-2, p53, and Efficacy of Adjuvant Therapy in Lymph Node-Positive Breast Cancer

1998 • 628 citations

Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group.

1998 • 602 citations

Meeting Highlights: International Consensus Panel on the Treatment of Primary Breast Cancer

2001 • 561 citations

Long-term survival rates of cancer patients achieved by the end of the 20th century: a period analysis

2002 • 532 citations

Compromised HOXA5 function can limit p53 expression in human breast tumours

2000 • 466 citations

Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling

2003 • 464 citations

Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy

1995 • 458 citations

The p53 Gene in Breast Cancer: Prognostic Value of Complementary DNA Sequencing Versus Immunohistochemistry

1996 • 387 citations

[Malignant tumors of the breast].

1960 • 271 citations

A Randomized Trial of Letrozole in Postmenopausal Women After Five Years of Tamoxifen Therapy for Early-Stage Breast Cancer

2004 • 264 citations

Tailored fluorouracil, epirubicin, and cyclophosphamide compared with marrow-supported high-dose chemotherapy as adjuvant treatment for high-risk breast cancer: a randomised trial

2000 • 259 citations

SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers.

2002 • 214 citations

Characterization of topoisomerase II alpha gene amplification and deletion in breast cancer.

1999 • 191 citations

Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group.

2000 • 177 citations

Characterization of topoisomerase II? gene amplification and deletion in breast cancer

1999 • 153 citations

Growth factor receptor cross-talk with estrogen receptor as a mechanism for tamoxifen resistance in breast cancer

2003 • 145 citations

HOXA5-Induced Apoptosis in Breast Cancer Cells Is Mediated by Caspases 2 and 8

2003 • 134 citations

Pre-validation and inference in microarrays

2002 • 127 citations

HOXA5 Regulates Expression of the Progesterone Receptor

2000 • 76 citations

Molecular classification of breast cancer patients by gene expression profiling*

2001 • 75 citations

Overexpression of cyclin E protein is associated with specific mutation types in the p53 gene and poor survival in human breast cancer

2003 • 71 citations

Identification of Transcriptional Targets of HOXA5

2005 • 52 citations

Correlation test to assess low-level processing of high-density oligonucleotide microarray data

2005 • 52 citations

Statistical Applications in Genetics and Molecular Biology

2003 • 13 citations