Binding of phorbol esters to high‐affinity sites on murine fibroblastic cells elicits a mitogenic response

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

1963 • 2,742 citations

Enzymatic iodination of polypeptides with 125I to high specific activity

1971 • 1,170 citations

Some current perspectives on chemical carcinogenesis in humans and experimental animals: Presidential Address.

1978 • 938 citations

Membrane receptors for hormones and neurotransmitters.

1976 • 573 citations

Hormonal regulation of peptide receptors and target cell responses

1979 • 531 citations

Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors

1979 • 517 citations

Tumor Promoters and the Mechanism of Tumor Promotion

1980 • 415 citations

Specific binding of phorbol ester tumor promoters

1980 • 364 citations

Phorbol esters and vasopressin stimulate DNA synthesis by a common mechanism

1980 • 334 citations

Serum rapidly stimulates ouabain-sensitive 86-RB+ influx in quiescent 3T3 cells.

1975 • 329 citations

Serum stimulates the Na+,K+ pump in quiescent fibroblasts by increasing Na+ entry.

1978 • 319 citations

Specific high affinity cell membrane receptors for biologically active phorbol and ingenol esters

1980 • 274 citations

Vasopressin stimulation of mouse 3T3 cell growth.

1979 • 210 citations

Stimulation of DNA synthesis by tumour promoter and pure mitogenic factors

1978 • 207 citations

Inhibition of epidermal growth factor binding to surface receptors by tumor promotors

1979 • 206 citations

Sequential Aspects of Chemical Carcinogenesis: Skin

1975 • 159 citations

Mechanism of tumor promoter inhibition of cellular binding of epidermal growth factor

1979 • 154 citations

Specific binding of phorbol ester tumor promoters to mouse skin

1980 • 152 citations

Cyclic AMP: a mitogenic signal for Swiss 3T3 cells.

1981 • 150 citations

Characterization of phorbol ester receptors and their down-modulation in GH4C1 rat pituitary cells.

1981 • 142 citations

Mechanisms of Tumor Promotion and Cocarcinogenesis

1979 • 142 citations

A possible naturally occurring tumor promoter, teleocidin B from Streptomyces

1979 • 130 citations

Vasopressin inhibition of epidermal growth factor binding to cultured mouse cells.

1981 • 130 citations

Similarity of teleocidin B and phorbol ester tumour promoters in effects on membrane receptors

1981 • 116 citations

Identification of receptors for phorbol ester tumor promoters in intact mammalian cells and of an inhibitor of receptor binding in biologic fluids.

1981 • 114 citations

Prostaglandin E-mediated mitogenic stimulation of mouse epidermis in vivo by divalent cation ionophore A 23187 and by tumor promoter 12-O-tetradecanoylphorbol-13-acetate.

1981 • 110 citations

Phorbol ester stimulation of Na influx and Na-K pump activity in swiss 3T3 cells

1981 • 106 citations

The tumor promoter 12‐0‐tetradecanoyl‐phorbol‐13‐acetate enhances the proliferative response of Balb/c‐3T3 cells to hormonal growth factors

1979 • 103 citations

Mechanisms of tumor promotion and cocarcinogenesis

1978 • 97 citations

Induction of cell division: Role of cell membrane sites

1972 • 90 citations

Specific binding of phorbol ester tumor promoters to intact primary epidermal cells from Sencar mice.

1981 • 89 citations

Melittin stimulates Na entry, Na-K pump activity and DNA synthesis in quiescent cultures of mouse cells

1981 • 88 citations

Calcium‐dependent stimulation of BALB/c 3T3 mouse cell DNA synthesis by a tumor‐promoting phorbol ester (PMA)

1976 • 88 citations

Kinetics and subcellular localization of specific [3H]phorbol 12, 13-dibutyrate binding by mouse brain.

1981 • 77 citations

Stimulation of ⁸⁶Rb⁺ and ³²P_i movements in 3T3 cells by prostaglandins and phorbol esters

1978 • 64 citations

Synergistic stimulation of early events and DNA synthesis by phorbol esters, polypeptide growth factors, and retinoids in cultured fibroblasts

1979 • 64 citations

Vasopressin-sensitive kidney adenylate cyclase. Structural requirements for attachment to the receptor and enzyme activation: studies with vasopressin analogues.

1975 • 61 citations

Retinoids enhance mitogenesis by tumour promotor and polypeptide growth factors

1979 • 49 citations

Neurohypophyseal hormone-responsive renal adenylate cyclase. II. Relationship between hormonal occupancy of neurohypophyseal hormone receptor sites and adenylate cyclase activation.

1978 • 29 citations

Vitamin B12 enhances the stimulation of DNA synthesis by serum in resting cultures of 3T6 cells

1977 • 27 citations