Pulmonary antiallergic and antiinflammatory effects of a novel, orallyactive phosphodiesterase IV inhibitor (WAY-127093B) in guinea pigs and rats

Characterization of allergen-induced bronchial hyperresponsiveness and airway inflammation in actively sensitized Brown-Norway rats

1991 • 164 citations

Inhibition of antigen-induced bronchoconstriction and eosinophil infiltration in the guinea pig by the cyclic AMP-specific phosphodiesterase inhibitor, rolipram.

1993 • 127 citations

Inflammatory Cell Populations in the Airways and Parenchyma after Antigen Challenge in the Rat

1993 • 82 citations

Effect of Acute and Chronic Antigen Inhalation on Airway Morphology and Responsiveness in Actively Sensitized Rats

1992 • 71 citations

Pulmonary antiallergic and bronchodilator effects of isozyme-selective phosphodiesterase inhibitors in guinea pigs.

1993 • 70 citations

Phosphodiesterase-IV inhibition, respiratory muscle relaxation and bronchodilation by WAY-PDA-641.

1994 • 30 citations

Model of bronchial allergic inflammation in the Brown Norway rat. Pharmacological modulation

1992 • 30 citations

Leukotrienes mediate antigen-induced airway hyper-reactivity in guinea pigs.

1994 • 11 citations