Octamer function in the chicken lambda immunoglobulin light chain promoter

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

A simple phase-extraction assay for chloramphenicol acyltransferase activity

1988 • 1,006 citations

A hyperconversion mechanism generates the chicken light chain preimmune repertoire

1987 • 693 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

Somatic hyperconversion diversifies the single VH gene of the chicken with a high incidence in the D region

1989 • 467 citations

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

1987 • 398 citations

A single rearrangement event generates most of the chicken immunoglobulin light chain diversity

1985 • 338 citations

Cell lines derived from avian lymphomas exhibit two distinct phenotypes

1985 • 213 citations

Chicken IgL gene rearrangement involves deletion of a circular episome and addition of single nonrandom nucleotides to both coding segments

1989 • 159 citations

Fine mapping of an immunoglobulin gene activator.

1984 • 144 citations

Complete sequence of a chicken lambda light chain immunoglobulin derived from the nucleotide sequence of its mRNA.

1983 • 86 citations

Promoter, enhancer and silencer elements regulate rearrangement of an immunoglobulin transgene.

1993 • 85 citations

Rearrangement of a chicken immunoglobulin gene occurs in the lymphoid lineage of transgenic mice

1987 • 64 citations

Use of filtered pipet tips to elute DNA from agarose gels.

1995 • 47 citations

Cell‐Type Specific Regulation of a K Immunoglobulin Gene by Promoter and Enhancer Elements

1986 • 21 citations

The chicken immunoglobulin λ light chain gene is transcriptionally controlled by a modularly organized enhancer and an octamer-dependent silencer

1995 • 17 citations