Increase of daunorubicin and vincristine accumulation in multidrug resistant human ovarian carcinoma cells by a monoclonal antibody reacting with P-glycoprotein

Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

1983 • 1,001 citations

The principles and practice of oncology

2001 • 966 citations

Isolation and expression of a complementary DNA that confers multidrug resistance

1986 • 808 citations

Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenetic studies.

1970 • 752 citations

Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance

1986 • 680 citations

Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies.

1986 • 561 citations

Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein.

1987 • 538 citations

Reversal of Adriamycin Resistance by Verapamil in Human Ovarian Cancer

1984 • 398 citations

Circumvention of vincristine and Adriamycin resistance in vitro and in vivo by calcium influx blockers.

1983 • 384 citations

Overexpression and amplification of five genes in a multidrug-resistant Chinese hamster ovary cell line.

1986 • 253 citations

Carrier-mediated transport of daunorubicin, adriamycin, and rubidazone in ehrlich ascites tumour cells

1978 • 121 citations

Reversal of Vinca alkaloid resistance but not multiple drug resistance in human leukemic cells by verapamil.

1986 • 96 citations

Decreased retention of actinomycin D as the basis for cross-resistance in anthracycline-resistant sublines of P388 leukemia.

1977 • 87 citations

Verapamil-mediated sensitization of doxorubicin-selected pleiotropic resistance in human sarcoma cells: selectivity for drugs which produce DNA scission.

1986 • 73 citations

Plasma membrane proteins and glycoproteins from chinese hamster cells sensitive and resistant to actinomycin D

1978 • 66 citations

Circumvention of resistance to anthracyclines by calcium antagonists and other membrane-perturbing agents.

1986 • 37 citations

Daunomycin accumulation in resistant tumor cells as a screening model for resistance modifying drugs: Role of protein binding

1987 • 29 citations

Factors governing the modulation of vinca-alkaloid resistance in doxorubicin-resistant cells by the calmodulin inhibitor trifluoperazine

1986 • 24 citations

Purine modulation of thymidine activity in L1210 leukemia cells in vitro

1982 • 14 citations