The complete sequence of botulinum neurotoxin type A and comparison with other clostridial neurotoxins.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1984 • 1,533 citations

Botulinum Neurotoxin and Tetanus Toxin

1989 • 393 citations

Tetanus toxin: primary structure, expression in E. coli, and homology with botulinum toxins.

1986 • 307 citations

In vivo and in vitro transcription of the Clostridium pasteurianum ferredoxin gene. Evidence for "extended" promoter elements in gram-positive organisms.

1986 • 252 citations

Interaction of 125I-labeled botulinum neurotoxins with nerve terminals. II. Autoradiographic evidence for its uptake into motor nerves by acceptor-mediated endocytosis.

1986 • 247 citations

Interaction of 125I-labeled botulinum neurotoxins with nerve terminals. I. Ultrastructural autoradiographic localization and quantitation of distinct membrane acceptors for types A and B on motor nerves.

1986 • 233 citations

Separation, purification, partial characterization and comparison of the heavy and light chains of botulinum neurotoxin types A, B, and E.

1985 • 161 citations

The complete nucleotide sequence of tetanus toxin

1986 • 159 citations

Structure and expression of the human haptoglobin locus.

1985 • 147 citations

Statistical analysis of a rapid in vivo method for the titration of the toxin of Clostridium botulinum

1966 • 134 citations

The tetanus toxin light chain inhibits exocytosis

1989 • 129 citations

Isolated Light Chain of Tetanus Toxin Inhibits Exocytosis: Studies in Digitonin‐Permeabilized Cells

1989 • 61 citations

Interaction of tetanus toxin with lipid vesicles at low pH. Protection of specific polypeptides against proteolysis.

1985 • 45 citations

Membrane integration and intracellular transport of the coronavirus glycoprotein E1, a class III membrane glycoprotein.

1988 • 45 citations

Characterization of bacteriophage nucleic acids obtained from Clostridium botulinum types C and D

1988 • 42 citations

Antigenicites of fragments of Clostridium botulinum type B derivative toxin

1975 • 38 citations

Arrangement of disulfide bridges and positions of sulfhydryl groups in tetanus toxin

1990 • 35 citations

Partial amino acid sequence of the heavy and light chains of botulinum neurotoxin type A

1984 • 30 citations

Partial amino acid sequences of botulinum neurotoxins types B and E

1985 • 29 citations

Effect of diethylpyrocarbonate on the biological activities of botulinum neurotoxin types A and E

1984 • 19 citations

Characterization of botulinum type a neurotoxin gene: Delineation of the N-terminal encoding region

1989 • 17 citations

Botulinum neurotoxin type B (strain 657): partial sequence and similarity with tetanus toxin

1988 • 16 citations