Participation of N-methyl-d-aspartate receptors on methylmercury-induced DNA damage in rat frontal cortex

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Oxidative Stress, Glutamate, and Neurodegenerative Disorders

1993 • 3,746 citations

The Toxicology of Mercury

1997 • 874 citations

Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat

2001 • 389 citations

Apoptosis and Its Relation to the Cell Cycle in the Developing Cerebral Cortex

1997 • 370 citations

Methylmercury developmental neurotoxicity: A comparison of effects in humans and animals

1990 • 267 citations

Neuronal injury and loss after traumatic brain injury: time course and regional variability

2001 • 202 citations

Early acute necrosis, delayed apoptosis and cytoskeletal breakdown in cultured cerebellar granule neurons exposed to methylmercury

2000 • 165 citations

Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures.

1991 • 161 citations

Mercuric compounds inhibit human monocyte function by inducing apoptosis: evidence for formation of reactive oxygen species, development of mitochondrial membrane permeability transition and loss of reductive reserve

1997 • 150 citations

Methylmercury-induced neurotoxicity in cerebral neuron culture is blocked by antioxidants and NMDA receptor antagonists.

1996 • 147 citations

Time course of degenerative alterations in nigral dopaminergic neurons following a 6-hydroxydopamine lesion

2000 • 137 citations

Methylmercury Neurotoxicity in Cultures of Human Neurons, Astrocytes, Neuroblastoma Cells

2001 • 133 citations

Release of ATP from cultured rat astrocytes elicited by glutamate receptor activation

1997 • 131 citations

MK-801, an receptor antagonist, blocks quinolinic acid-induced lipid peroxidation in rat corpus striatum

1993 • 127 citations

Mitochondrial viability and apoptosis induced by aluminum, mercuric mercury and methylmercury in cell lines of neural origin

2004 • 115 citations

Status epilepticus-induced neuronal damage in the rat amygdaloid complex: distribution, time-course and mechanisms

1999 • 103 citations

Expression and activation of caspase 3 following status epilepticus in the rat

2003 • 95 citations

Methylmercury Affects Multiple Subtypes of Calcium Channels in Rat Cerebellar Granule Cells

2000 • 95 citations

In vivo protection of a water-soluble derivative of vitamin E, Trolox, against methylmercury-intoxication in the rat

2001 • 94 citations

The c‐Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK‐ERK and Akt‐independent mechanism

2004 • 93 citations

Apoptotic process of cerebellar degeneration in experimental methylmercury intoxication of rats

1995 • 93 citations

Antioxidants J811 and 17?-estradiol protect cerebellar granule cells from methylmercury-induced apoptotic cell death

2000 • 91 citations

The Consequences of Methylmercury Exposure on Interactive Functions between Astrocytes and Neurons

2002 • 85 citations

Evidence for Interactions between Intracellular Calcium Stores during Methylmercury-Induced Intracellular Calcium Dysregulation in Rat Cerebellar Granule Neurons

2003 • 82 citations

Methylmercury and H2O2 provoke lysosomal damage in human astrocytoma D384 cells followed by apoptosis

2001 • 80 citations

Involvement of enhanced sensitivity of N-methyl-d-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity

2001 • 80 citations

Methylmercury increases glutamate extracellular levels in frontal cortex of awake rats

2002 • 80 citations

Methylmercury enhances arachidonic acid release and cytosolic phospholipase A2 expression in primary cultures of neonatal astrocytes

2002 • 79 citations

Time course assessment of methylmercury effects on C6 glioma cells: submicromolar concentrations induce oxidative DNA damage and apoptosis

2002 • 72 citations

Formation of the Base Modification 8‐Hydroxyl‐2′ ‐ Deoxyguanosine and DNA Fragmentation Following Seizures Induced by Systemic Kainic Acid in the Rat

2000 • 69 citations

The role of intracellular glutathione in methylmercury-induced toxicity in embryonic neuronal cells.

1999 • 68 citations

Translocation of apoptosis‐inducing factor in cerebellar granule cells exposed to neurotoxic agents inducing oxidative stress

2002 • 63 citations

Astrocytes as modulators of mercury-induced neurotoxicity.

1996 • 52 citations

Functional Change of NMDA Receptors Related to Enhancement of Susceptibility to Neurotoxicity in the Developing Pontine Nucleus

1998 • 49 citations

Involvement of caspase 3-like protease in methylmercury-induced apoptosis of primary cultured rat cerebral microglia

2000 • 48 citations

Cellular mechanisms underlying the increase in cytosolic free calcium concentration induced by methylmercury in cerebrocortical synaptosomes from guinea pig.

1989 • 44 citations

Induction of apoptosis by mercury compounds depends on maturation and is not associated with microglial activation

1998 • 42 citations

Effects of methylmercury on electrical responses of neuroblastoma cells.

1982 • 37 citations

Methylmercury Induces Apoptosis in Cultured Rat Dorsal Root Ganglion Neurons

2003 • 37 citations

An evaluation of the role of extracellular amino acids in the delayed neurodegeneration induced by quinolinic acid in the rat striatum

1993 • 34 citations

Protection of methylmercury effects on the in vivo dopamine release by NMDA receptor antagonists and nitric oxide synthase inhibitors

2002 • 28 citations

Two Temporal Stages of Oligodendroglial Response to Excitotoxic Lesion in the Gray Matter of the Adult Rat Brain

2001 • 24 citations

Activation of microglia in kainic acid induced rat retinal apoptosis

2000 • 4 citations