Antibody to E- and L-Selectin Does Not Prevent Lung Injury or Mortality in Septic Baboons

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

J Heart Lung Transplant 2021;40(4).

2021 • 6,783 citations

Endothelial Leukocyte Adhesion Molecule 1: an Inducible Receptor for Neutrophils Related to Complement Regulatory Proteins and Lectins

1989 • 2,045 citations

Selectins.

1993 • 869 citations

Measurement of continuous distributions of ventilation-perfusion ratios: theory

1974 • 801 citations

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells.

1986 • 748 citations

State of the Art

1983 • 655 citations

Adult Respiratory-Distress Syndrome

1982 • 554 citations

Soluble L-selectin is present in human plasma at high levels and retains functional activity.

1992 • 422 citations

Function and regulation of the neutrophil MEL-14 antigen in vivo: comparison with LFA-1 and MAC-1.

1989 • 413 citations

Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats.

1991 • 398 citations

Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis.

1993 • 353 citations

Role of selectiris In development of adult respiratory distress syndrome

1994 • 254 citations

Neutrophil margination, sequestration, and emigration in the lungs of L-selectin-deficient mice.

1997 • 154 citations

Expression of endothelial leukocyte adhesion molecule-1 in septic but not traumatic/hypovolemic shock in the baboon.

1991 • 146 citations

Role of selectins in local and remote tissue injury following ischemia and reperfusion.

1994 • 143 citations

Requirements for L-selectin in neutrophil-mediated lung injury in rats.

1994 • 133 citations

Chemotactic activity in bronchoalveolar lavage fluid from patients with adult respiratory distress syndrome.

1985 • 112 citations

Adhesion Molecules in the Lung: An Overview

1993 • 105 citations

Characterization of a functionally important and evolutionarily well-conserved epitope mapped to the short consensus repeats of E-selectin and L-selectin.

1992 • 80 citations

Monoclonal antibody blockade of L-selectin inhibits mononuclear leukocyte recruitment to inflammatory sites in vivo.

1994 • 75 citations

Role of inflammatory cells in the metabolic activation of polycyclic aromatic hydrocarbons in mouse skin

1987 • 65 citations

A role for ELAM-1 in the pathogenesis of MOF during septic shock

1992 • 61 citations

A dual-binding antibody to E- and L-selectin attenuates sepsis-induced lung injury.

1995 • 59 citations

Intratracheal administration of endotoxin and cytokines: VIII. LPS induces E-selectin expression; anti-E-selectin and soluble E-selectin inhibit acute inflammation

1994 • 51 citations

Natural surfactant and hyperoxic lung injury in primates. I. Physiology and biochemistry

1994 • 38 citations

Signaling by E-selectin and ICAM-1 Induces Endothelial Tissue Factor Production via Autocrine Secretion of Platelet-Activating Factor and Tumor Necrosis Factor α

1995 • 34 citations

Survival in lung reperfusion injury is improved by an antibody that binds and inhibits L- and E-selectin.

1994 • 32 citations

Protective effects of combined adhesion molecule blockade in models of acute lung injury.

1996 • 28 citations

Natural surfactant and hyperoxic lung injury in primates. II. Morphometric analyses

1994 • 22 citations

Adhesion Molecules and the Lung

1996 • 17 citations

Changes in the lung after prolonged positive pressure ventilation in normal baboons

1997 • 8 citations

V̇a/Q̇ abnormalities during gram negative sepsis

1996 • 6 citations