An introduction to the use of interim data analyses in clinical trials

Statistical power analysis for the behavioral sciences

1990 • 65,781 citations

A Multiple Testing Procedure for Clinical Trials

1979 • 3,139 citations

Statistical Power Analysis for the Behavioral Sciences

1977 • 2,262 citations

Power and sample size calculations

1990 • 2,000 citations

Group sequential methods in the design and analysis of clinical trials

1977 • 1,679 citations

The Importance of Beta, the Type II Error and Sample Size in the Design and Interpretation of the Randomized Control Trial

1978 • 1,634 citations

Statistical Methods for Rates and Proportions.

1973 • 1,326 citations

Introduction to sample size determination and power analysis for clinical trials

1981 • 996 citations

Clinical Trials: Design, Conduct, and Analysis

1986 • 782 citations

The Design and Analysis of Sequential Clinical Trials.

1985 • 655 citations

Statistical Methods for Rates and Proportions

1974 • 555 citations

Sequential Medical Trials

1976 • 461 citations

Designs for group sequential tests

1984 • 352 citations

Interim Analyses for Randomized Clinical Trials: The Group Sequential Approach

1982 • 261 citations

Sequential Methods in Statistics.

1987 • 252 citations

Approaches to sample size estimation in the design of clinical trials—a review

1984 • 251 citations

Interim Analyses in Randomized Clinical Trials: Ramifications and Guidelines for Practitioners

1987 • 200 citations

The Design and Analysis of Sequential Clinical Trials.

1983 • 190 citations

Clinical trials: Design, conduct, and analysis

1987 • 166 citations

Sequential Medical Trials

1961 • 146 citations

Impact of multiple comparisons in randomized clinical trials

1987 • 91 citations

Sequential Methods in Statistics.

1987 • 74 citations

The beta error and sample size determination in clinical trials in emergency medicine

1987 • 61 citations

Introduction to biostatistics: Part 3, sensitivity, specificity, predictive value, and hypothesis testing

1990 • 59 citations

Statistical Considerations for Performing Multiple Tests in a Single Experiment. 1. Introduction

1988 • 58 citations

Statistical Considerations for Performing Multiple Tests in a Single Experiment. 2. Comparisons Among Several Therapies

1988 • 40 citations

Statistical Considerations for Performing Multiple Tests in a Single Experiment. 3. Repeated Measures Over Time

1988 • 26 citations

Sequential clinical trials in emergency medicine

1990 • 23 citations

Statistical Considerations for Performing Multiple Tests in a Single Experiment. 6. Testing Accumulating Data Repeatedly Over Time

1988 • 19 citations

Statistical concepts and methods for the reader of clinical studies in emergency medicine

1991 • 17 citations

Statistics for clinicians. 12. Sequential methods.

1981 • 4 citations