Nongenomic regulation of extracellular matrix events by vitamin D metabolites

Differential expression of phenotype by resting zone and growth region costochondral chondrocytes in vitro

1988 • 193 citations

Demonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3.

1993 • 182 citations

Effect of 1,25-dihydroxyvitamin D3 on phospholipid metabolism in chick duodenal mucosal cell. Relationship to its mechanism of action.

1981 • 169 citations

1,25(OH)2 vitamin D3 stimulates membrane phosphoinositide turnover, activates protein kinase C, and increases cytosolic calcium in rat colonic epithelium.

1990 • 165 citations

Direct Effects of 1,25-Dihydroxyvitamin D₃and 24,25-Dihydroxyvitamin D3 on Growth Zone and Resting Zone Chondrocyte Membrane Alkaline Phosphatase and Phospholipase-A2 Specific Activities*

1988 • 153 citations

The Effects of Vitamin D Metabolites on Phospholipase A₂Activity of Growth Zone and Resting Zone Cartilage Cellsin Vitro*

1988 • 153 citations

The Effects of Vitamin D Metabolites on the Plasma and Matrix Vesicle Membranes of Growth and Resting Cartilage Cellsin Vitro*

1988 • 145 citations

Effects of vitamin D metabolites on collagen production and cell proliferation of growth zone and resting zone cartilage cells in vitro

1989 • 140 citations

Nongenomic Actions of 1,25-Dihydroxyvitamin D₃in Rat Osteosarcoma Cells: Structure-Function Studies Using Ligand Analogs*

1991 • 126 citations

Matrix vesicles produced by osteoblast-like cells in culture become significantly enriched in proteoglycan-degrading metalloproteinases after addition of ?-Glycerophosphate and ascorbic acid

1994 • 110 citations

Effect of vitamin D metabolites on the expression of alkaline phosphatase activity by epiphyseal hypertrophic chondrocytes in primary cell culture

1986 • 109 citations

Role of changes in membrane lipid structure in the action of 1,25-dihydroxyvitamin D3.

1982 • 108 citations

Evidence for Involvement of Protein Kinase C and Cyclic Adenosine 3’,5’ Monophosphate-Dependent Protein Kinase in the 1,25-Dihydroxy-Vitamin D₃-Mediated Rapid Stimulation of Intestinal Calcium Transport, (Tr anscaltachia)*

1990 • 106 citations

Production of 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 by growth zone and resting zone chondrocytes is dependent on cell maturation and is regulated by hormones and growth factors.

1992 • 105 citations

Maturation‐dependent regulation of protein kinase C activity by vitamin D₃ metabolites in chondrocyte cultures

1993 • 103 citations

Matrix vesicles are enriched in metalloproteinases that degrade proteoglycans

1992 • 102 citations

Glycoprotein Motility and Dynamic Domains in Fluid Plasma Membranes

1993 • 89 citations

Regulation of arachidonic acid turnover by 1,25-(OH)2D3 and 24,25-(OH)2D3 in growth zone and resting zone chondrocyte cultures

1990 • 79 citations

Nongenomic regulation of chondrocyte membrane fluidity by 1,25-(OH)2D3 and 24,25-(OH)2D3 is dependent on cell maturation

1993 • 78 citations

Specific nuclear uptake of 24,25‐dihydroxycholecalciferol, a vitamin D₃ metabolite biologically active in cartilage

1980 • 78 citations

Regulation of prostaglandin E2 production by vitamin D metabolites in growth zone and resting zone chondrocyte cultures is dependent on cell maturation

1992 • 76 citations

Direct effects of transforming growth factor-beta on chondrocytes are modulated by vitamin D metabolites in a cell maturation-specific manner.

1993 • 75 citations

Basic fibroblast growth factor affects DNA synthesis and cell function and activates multiple signalling pathways in rat thyroid FRTL-5 and pituitary GH3 cells

1990 • 74 citations

1,25-Dihydroxyvitamin D3 analog structure-function assessment of the rapid stimulation of intestinal calcium absorption (transcaltachia)

1992 • 74 citations

Calcification in Biological Systems

1961 • 74 citations

Studies of mineralization in tissue culture: optimal conditions for cartilage calcification

1992 • 73 citations

1,25-(OH)2D3 and 24,25-(OH)2D3 regulation of arachidonic acid turnover in chondrocyte cultures is cell maturation-specific and may involve direct effects on phospholipase A2

1992 • 60 citations

Effects of vitamin D metabolites on healing of low phosphate, vitamin D-deficient induced rickets in rats

1985 • 60 citations

Effects of serum calcium and phosphorus on skeletal mineralization in vitamin D-deficient rats

1986 • 58 citations

Evidence for the functional involvement of protein kinase C in the action of 1,25-dihydroxyvitamin D3 in bone.

1992 • 58 citations

Effect of 1,25(OH)2D3 and 24,25(OH)2D3 on calcium ion fluxes in costochondral chondrocyte cultures

1990 • 58 citations

1,25-Dihydroxyvitamin D3 stimulates both alkaline phosphatase gene transcription and mRNA stability in human bone cells

1991 • 56 citations

Healing of rachitic lesions in chicks by 24R,25-dihydroxycholecalciferol administered locally into bone

1987 • 43 citations

α2-HS-glycoprotein: Expression in chondrocytes and augmentation of alkaline phosphatase and phospholipase A2 activity

1991 • 40 citations

Distribution and subcellular immunolocalization of 1,25-dihydroxyvitamin D3 receptors in rat epiphyseal cartilage.

1993 • 40 citations

Inhibition of 1,25-(OH)2D3- and 24,25-(OH)2D3-dependent stimulation of alkaline phosphatase activity by A23187 suggests a role for calcium in the mechanism of vitamin D regulation of chondrocyte cultures

1991 • 32 citations

Autoradiographic localization of 24R,25-dihydroxyvitamin D3 in epiphyseal cartilage

1985 • 31 citations

Studies of matrix vesicle-induced mineralization in a gelatin gel

1992 • 29 citations

Comparative Morphological and Biochemical Analysis of Hypertrophic, Non-Hypertrophic and L, 25(Oh)₂d₃Treated Non-Hypertrophic Chondrocytes

1990 • 28 citations

The role of matrix vesicles in calcification

1978 • 25 citations

Direct effects of transforming growth factor-beta on chondrocytes are modulated by vitamin D metabolites in a cell maturation-specific manner

1993 • 15 citations

Binding of the Occupied Vitamin D Receptor (VDR) to Extra-Nuclear Sites: A Potential Mechanism of Nongenomic Actions of 1a,25(OH)₂D₃

1994 • 6 citations