Chemoprevention of Prostate Cancer: Concepts and Strategies

Cancer statistics, 1998

1998 • 2,407 citations

Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group

1996 • 2,404 citations

Treatment of Colonic and Rectal Adenomas with Sulindac in Familial Adenomatous Polyposis

1993 • 1,739 citations

Prevention of Second Primary Tumors with Isotretinoin in Squamous-Cell Carcinoma of the Head and Neck

1990 • 1,375 citations

Prostate Cancer and Supplementation With α-Tocopherol and β-Carotene: Incidence and Mortality in a Controlled Trial

1998 • 923 citations

Decreased incidence of prostate cancer with selenium supplementation: results of a double‐blind cancer prevention trial

1998 • 682 citations

Intraductal dysplasia: A premalignant lesion of the prostate

1986 • 584 citations

Prostatic Intra-Epithelial Neoplasia and Early Invasion in Prostate Cancer

1987 • 536 citations

NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells.

1998 • 439 citations

Vitamin D and prostate cancer: a prediagnostic study with stored sera.

1993 • 357 citations

Arachidonic Acid Stimulates Prostate Cancer Cell Growth: Critical Role of 5-Lipoxygenase

1997 • 262 citations

Androgen Metabolism and Prostate Cancer: Establishing a Model of Genetic Susceptibility

1999 • 261 citations

Prevention of primary prostate cancer in Lobund-Wistar rats by N-(4-hydroxyphenyl)retinamide.

1991 • 178 citations

Significance of prosttic intraepithelial neoplasia on prostate needle biopsy

1991 • 168 citations

Phenotype and Genotype of Advanced Premalignant Head and Neck Lesions After Chemopreventive Therapy

1998 • 166 citations

Design of the Prostate Cancer Prevention Trial (PCPT)

1995 • 135 citations

Prostatic intraepithelial neoplasia

2000 • 113 citations

Approaches to the development and marketing approval of drugs that prevent cancer.

1995 • 113 citations

Prostatic intraepithelial neoplasia (PIN): Current concepts

1992 • 111 citations

Prostatic intraepithelial neoplasia: A premalignant lesion

1992 • 100 citations

Commentary concerning demonstration of safety and efficacy of investigational anticancer agents in clinical trials.

1991 • 85 citations

Progress in clinical chemoprevention.

1997 • 76 citations

Androgen Deprivation as a Strategy for Prostate Cancer Chemoprevention

1997 • 73 citations

A Phase I Trial of β-<italic>all-trans</italic>-Retinoic Acid Delivered via a Collagen Sponge and a Cervical Cap for Mild or Moderate Intraepithelial Cervical Neoplasia<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1983 • 68 citations

Strategies for identification and clinical evaluation of promising chemopreventive agents.

1996 • 55 citations

Surrogate endpoint biomarkers for phase II cancer chemoprevention trials.

1994 • 53 citations

Properties of Intraepithelial Neoplasia Relevant to Cancer Chemoprevention and to the Development of Surrogate End Points for Clinical Trials

1997 • 38 citations

Chemoprevention in prostate cancer: The role of difluoromethylornithine (DFMO)

1992 • 36 citations

Introductory remarks: Development of chemopreventive agents for prostate cancer

1992 • 20 citations

Inhibition of Chemical Carcinogenesis

1995 • 18 citations