Fludarabine induces apoptosis, activation, and allogenicity in human endothelial and epithelial cells: protective effect of defibrotide

Nonmyeloablative Stem Cell Transplantation and Cell Therapy as an Alternative to Conventional Bone Marrow Transplantation With Lethal Cytoreduction for the Treatment of Malignant and Nonmalignant Hematologic Diseases

1998 • 1,984 citations

Nonmyeloablative Stem Cell Transplantation and Cell Therapy as an Alternative to Conventional Bone Marrow Transplantation With Lethal Cytoreduction for the Treatment of Malignant and Nonmalignant Hematologic Diseases

1998 • 1,765 citations

HMEC-1: Establishment of an Immortalized Human Microvascular Endothelial Cell Line

1992 • 1,258 citations

REGULATION OF IMMUNE RESPONSES THROUGH INHIBITORY RECEPTORS

1999 • 947 citations

Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators

1993 • 726 citations

Cytokine dysregulation and acute graft-versus-host disease

1992 • 617 citations

Increased serum levels of tumor necrosis factor alpha precede major complications of bone marrow transplantation [see comments]

1990 • 591 citations

Cytokine dysregulation and acute graft-versus-host disease

1992 • 565 citations

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO

1974 • 488 citations

Interstitial Pneumonitis After Bone Marrow Transplantation

1986 • 381 citations

Pathophysiologic mechanisms of acute graft-vs.-host disease

1999 • 348 citations

Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in vivo.

1994 • 333 citations

Protein kinase C mediates basic fibroblast growth factor protection of endothelial cells against radiation-induced apoptosis.

1994 • 255 citations

Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumor cells undergoing apoptosis.

1992 • 250 citations

Mini-allografts: ongoing trials in humans

2000 • 226 citations

Critical involvement of transmembrane tumor necrosis factor-alpha in endothelial programmed cell death mediated by ionizing radiation and bacterial endotoxin

1995 • 207 citations

Microangiopathy in patients on cyclosporine prophylaxis who developed acute graft-versus-host disease after HLA-identical bone marrow transplantation

1989 • 197 citations

Defibrotide for the treatment of hepatic veno‐occlusive disease: results of the European compassionate‐use study

2000 • 184 citations

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO

1974 • 177 citations

Microangiopathy in patients on cyclosporine prophylaxis who developed acute graft-versus-host disease after HLA-identical bone marrow transplantation

1989 • 173 citations

Nucleotide Requirements for the in Vitro Activation of the Apoptosis Protein-activating Factor-1-mediated Caspase Pathway

2000 • 171 citations

Defibrotide for the treatment of hepatic veno-occlusive disease: results of the European compassionate-use study

2000 • 127 citations

Evidence that sustained growth suppression of intestinal anaerobic bacteria reduces the risk of acute graft-versus-host disease after sibling marrow transplantation

1992 • 124 citations

Low-intensity conditioning is sufficient to ensure engraftment in matched unrelated bone marrow transplantation

2001 • 103 citations

Interactions between T lymphocytes and endothelial cells in allograft rejection

1998 • 96 citations

Allogeneic Hematopoietic Stem-Cell Transplantation After Nonmyeloablative Preparative Regimens: Impact of Pretransplantation and Posttransplantation Factors on Outcome

2001 • 93 citations

Peripheral Blood Mononuclear Cells Induce Programmed Cell Death in Human Endothelial Cells and May Prevent Repair: Role of Cytokines

1997 • 87 citations

Dose-reduced conditioning for allogeneic blood stem cell transplantation: durable engraftment without antithymocyte globulin

2000 • 81 citations

Rapid achievement of complete donor chimerism and low regimen-related toxicity after reduced conditioning with fludarabine, carmustine, melphalan and allogeneic transplantation

2000 • 70 citations

Human Vascular Endothelial Cells Favor Clonal Expansion of Unusual Alloreactive CTL

1999 • 68 citations

INFLUENCE OF BACTERIAL ENDOTOXIN ON RADIATION-INDUCED ACTIVATION OF HUMAN ENDOTHELIAL CELLS IN VITRO AND IN VIVO

1996 • 42 citations

ACUTE GRAFT-VERSUS-HOST-LIKE DISEASE INDUCED BY TRANSPLANTATION OF HUMAN ACTIVATED NATURAL KILLER CELLS INTO SCID MICE

1993 • 41 citations

Gene deletion, a mechanism of induced mutation by arabinosyl nucleosides

1989 • 29 citations

Prevention and Treatment of Veno-Occlusive Disease

2001 • 29 citations

The prevention of benzene-induced genotoxicity in mice by indomethacin

1989 • 23 citations

INFLUENCE OF BACTERIAL ENDOTOXIN ON RADIATION-INDUCED ACTIVATION OF HUMAN ENDOTHELIAL CELLS IN VITRO AND IN VIVO

1997 • 23 citations

Defibrotide in Recurrent Thrombotic Thrombocytopenic Purpura

2000 • 18 citations

Protective Effect of Defibrotide on Perfusion Induced Endothelial Damage

2000 • 11 citations

Accessory Function of Endothelial Cells in Anti‐CD3‐Induced T‐Cell Proliferation: Synergism with Monocytes

1992 • 10 citations

Defibrotide Normalizes Cardiovascular Function Hampered by Established Atherosclerosis in the Rabbit

2000 • 6 citations

Novel treatment strategies in chronic lymphocytic leukemia

2001 • 6 citations

Protectant Activity of Defibrotide in Cardioplegia Followed by IschernialReperfusion Injury in the Isolated Rat Heart

1999 • 5 citations