Partial characterization of a small, multi-copy plasmid from Streptomyces espinosus and the derivation of a high copy-number deletion mutant

Methods in Enzymology , Vol

1966 • 26,261 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose-ethidium bromide electrophoresis

1973 • 1,616 citations

[31] Electron microscope heteroduplex methods for mapping regions of base sequence homology in nucleic acids

1971 • 1,605 citations

Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event

1970 • 770 citations

Mapping of Deletions and Substitutions in Heteroduplex DNA Molecules of Bacteriophage Lambda by Electron Microscopy

1969 • 408 citations

Phage lambda receptor chromosomes for DNA fragments made with restriction endonuclease III of Haemophilus influenzae and restriction endonuclease I of Escherichia coli

1975 • 351 citations

Formation and Reversion of Streptomycete Protoplasts: Cultural Condition and Morphological Study

1974 • 306 citations

DNA cloning in Streptomyces: resistance genes from antibiotic-producing species

1980 • 300 citations

Transformation of plasmid DNA into Streptomyces at high frequency

1978 • 278 citations

Genetics of Industrial Microorganisms

1979 • 208 citations

Plasmid copy number control: isolation and characterization of high-copy-number mutants of plasmid pE194

1979 • 202 citations

A DNA cloning system for interspecies gene transfer in antibiotic-producing Streptomyces

1980 • 164 citations

A single base-pair alteration is responsible for the DNA overproduction phenotype of a plasmid copy-number mutant

1981 • 99 citations

Isolation of covalently closed circular deoxyribonucleic acid from Streptomyces coelicolor A3(2)

1975 • 98 citations

Cloning and expression in streptomyces lividans of antibiotic resistance genes derived from Escherichia coli

1981 • 81 citations

Estimate of the Genome Size by Renaturation Studies in Streptomyces

1975 • 69 citations

Replication control system in Lambda dv

1981 • 68 citations

DNA cloning in Streptomyces: a bifunctional replicon comprising pBR322 inserted into a Streptomyces phage

1980 • 68 citations

Estimate of the Genome Size by Renaturation Studies in Streptomyces

1975 • 45 citations

Nonintegrated plasmid-folded chromosome complexes

1978 • 43 citations

Segregation kinetics of colicinogenic factor Col E1 from a bacterial population temperature sensitive for DNA polymerase I

1973 • 42 citations

Isolation and characterization of ColE1-derived plasmid copy-number mutant.

1978 • 41 citations

Isolation and characterization of plasmids from Streptomyces.

1979 • 35 citations

Extraction and characterization of plasmids from macrolide antibiotic-producing Streptomycetes.

1981 • 31 citations

Characterization of a replication mutant of the bacteriocinogenic plasmid Clo DF13

1976 • 18 citations

Isolation and physical characterization of streptomycete plasmids

1981 • 18 citations

A comparison of DNA cleavage by the restriction enzymes SalPI and PstI

1980 • 17 citations

Physical characterization of plasmids from Streptomyces kasugaensis MB273

1981 • 16 citations