Health effects of obstructive sleep apnoea and the effectiveness of continuous positive airways pressure: a systematic review of the research evidence

The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults

1993 • 10,139 citations

Applied Logistic Regression.

1990 • 7,187 citations

Epidemiology in Medicine

1987 • 2,189 citations

Epidemiology in Medicine.

1988 • 1,933 citations

Mortality and Apnea Index in Obstructive Sleep Apnea

1988 • 1,527 citations

Rules of Evidence and Clinical Recommendations on the Use of Antithrombotic Agents

1989 • 1,348 citations

Objective Measurement of Patterns of Nasal CPAP Use by Patients with Obstructive Sleep Apnea

1993 • 1,306 citations

Obstructive Sleep Apnea

1996 • 1,295 citations

Breast cancer screening with mammography: overview of Swedish randomised trials

1993 • 981 citations

Cardiac arrhythmia and conduction disturbances during sleep in 400 patients with sleep apnea syndrome

1983 • 941 citations

Association of sleep apnoea with myocardial infarction in men

1990 • 922 citations

Predictors and prevalence of obstructive sleep apnoea and snoring in 1001 middle aged men.

1991 • 645 citations

Automobile Accidents Involving Patients with Obstructive Sleep Apnea

1988 • 605 citations

Effect of continuous positive airway pressure treatment on daytime function in sleep apnoea/hypopnoea syndrome

1994 • 596 citations

Investigating the Relationship Between Stroke and Obstructive Sleep Apnea

1996 • 580 citations

Sleep Apnea and Hypertension: A Population-based Study

1994 • 559 citations

REDUCTION OF BREAST CANCER MORTALITY THROUGH MASS SCREENING WITH MODERN MAMMOGRAPHY

1984 • 495 citations

A Randomized Crossover Study of an Oral Appliance vs Nasal-Continuous Positive Airway Pressure in the Treatment of Mild-Moderate Obstructive Sleep Apnea

1996 • 484 citations

Weight Loss in Mildly to Moderately Obese Patients with Obstructive Sleep Apnea

1985 • 475 citations

Some Epidemiological Data on Snoring and Cardiocirculatory Disturbances

1980 • 470 citations

Randomised, prospective, single-blind comparison of laparoscopic versus small-incision cholecystectomy

1996 • 430 citations

Mortality in Sleep Apnea Patients: A Multivariate Analysis of Risk Factors

1995 • 400 citations

Effects of One Night without Nasal CPAP Treatment on Sleep and Sleepiness in Patients with Obstructive Sleep Apnea

1993 • 389 citations

EVALUATION OF SCREENING FOR BREAST CANCER IN A NON-RANDOMISED STUDY (THE DOM PROJECT) BY MEANS OF A CASE-CONTROL STUDY

1984 • 377 citations

Nasal CPAP: an objective evaluation of patient compliance.

1994 • 360 citations

Compliance with CPAP therapy in patients with the sleep apnoea/hypopnoea syndrome.

1994 • 358 citations

Automobile Accidents in Patients with Sleep Disorders

1989 • 355 citations

Sleep-Disordered Breathing in Men With Coronary Artery Disease

1996 • 339 citations

Snoring and sleep apnoea in men: association with central obesity and hypertension.

1993 • 331 citations

Role of daytime hypoxemia in the pathogenesis of right heart failure in the obstructive sleep apnea syndrome.

1985 • 320 citations

Self-Reported Use of CPAP and Benefits of CPAP Therapy

1996 • 291 citations

Long-term Compliance with Nasal Continuous Positive Airway Pressure Therapy of Obstructive Sleep Apnea

1990 • 285 citations

Relationship of Ventricular Ectopy to Oxyhemoglobin Desaturation in Patients with Obstructive Sleep Apnea

1985 • 283 citations

Snoring and the risk of ischemic brain infarction.

1991 • 272 citations

The Clinical Use of the Multiple Sleep Latency Test

1992 • 271 citations

Daytime Pulmonary Hypertension in Patients with Obstructive Sleep Apnea Syndrome

1988 • 268 citations

Traffic Accidents in Commercial Long-Haul Truck Drivers: The Influence of Sleep-Disordered Breathing and Obesity

1994 • 267 citations

Vigilance and Automobile Accidents in Patients With Sleep Apnea or Narcolepsy

1995 • 247 citations

Predictive Factors of Long-term Compliance With Nasal Continuous Positive Airway Pressure Treatment in Sleep Apnea Syndrome

1994 • 246 citations

Efficacy of screening mammography. A meta-analysis

1995 • 241 citations

Craniofacial structure and obstructive sleep apnea syndrome — a qualitative analysis and meta-analysis of the literature

1996 • 236 citations

Pulmonary hypertension and hypoxemia in obstructive sleep apnea syndrome.

1994 • 232 citations

Daytime Hypertension in Obstructive Sleep Apnea

1991 • 231 citations

High prevalence of hypertension in sleep apnea patients independent of obesity.

1994 • 230 citations

Cardiac arrhythmias and conduction disturbances in the sleep apnea syndrome

1982 • 226 citations

Cardiac Arrhythmias, Snoring, and Sleep Apnea

1994 • 220 citations

Effect of Nasal Continuous Positive Airway Pressure During Sleep on 24-hour Blood Pressure in Obstructive Sleep Apnea

1993 • 210 citations

Driving Simulator Performance in Patients with Sleep Apnea

1989 • 203 citations

Sleep apnea in patients with hemispheric stroke

1995 • 194 citations

Insulin Levels, Blood Pressure and Sleep Apnea

1994 • 193 citations

Long-term Acceptance of Continuous Positive Airway Pressure in Obstructive Sleep Apnea

1991 • 191 citations

Pulmonary Hypertension, Hypoxemia, and Hypercapnia in Obstructive Sleep Apnea Patients

1989 • 188 citations

Self-Reported vs Measured Compliance with Nasal CPAP for Obstructive Sleep Apnea

1993 • 181 citations

Daytime sleepiness, cognitive performance and mood after continuous positive airway pressure for the sleep apnoea/hypopnoea syndrome.

1993 • 180 citations

Sleep apnea and mortality in an aged cohort.

1988 • 179 citations

Recovery of Alertness After CPAP in Apnea

1989 • 179 citations

Blood Pressure and Sleep Apnea: Results of Long-Term Nasal Continuous Positive Airway Pressure Therapy

1991 • 177 citations

Sleep Apnea and Cardiac Arrhythmias: Is There a Relationship?

1993 • 166 citations

Neuropsychologic Symptoms in Obstructive Sleep Apnea Improve after Treatment with Nasal Continuous Positive Airway Pressure

1988 • 163 citations

Cardiovascular Effects of Sleep Disorders

1990 • 162 citations

Pathogenesis of obstructive sleep apnoea/hypopnoea syndrome

1994 • 162 citations

Adiposity and Cardiovascular Risk Factors in Men With Obstructive Sleep Apnea

1993 • 161 citations

Epidemiology of snoring and obstructive sleep apnoea in a Danish population, age 30–60

1992 • 153 citations

Pulmonary hypertension in obstructive sleep apnoea

1995 • 153 citations

Sleep habits and sleep disturbances among the elderly—an epidemiological survey

1993 • 152 citations

Compliance and side effects in sleep apnea patients treated with nasal continuous positive airway pressure.

1989 • 146 citations

Are Breathing Disturbances in Elderly Equivalent to Sleep Apnea Syndrome?

1994 • 146 citations

Acceptance of CPAP Therapy for Sleep Apnea

1991 • 143 citations

IS SNORING A CAUSE OF VASCULAR DISEASE?

1989 • 140 citations

Long-Term Nasal Continuous Positive Airway Pressure Administration Can Normalize Hypertension in Obstructive Sleep Apnea Patients

1993 • 139 citations

Sleep Apnea in Female Patients in a Nursing Home

1989 • 137 citations

Relation between systemic hypertension and sleep hypoxaemia or snoring: analysis in 748 men drawn from general practice.

1990 • 130 citations

The Effect of Positive Reinforcement on Hourly Compliance in Nasal Continuous Positive Airway Pressure Users with Obstructive Sleep Apnea

1991 • 128 citations

Do Patients with Sleep Apnea Die in Their Sleep?

1988 • 125 citations

Treatment of Obstructive Sleep Apnea

1990 • 125 citations

Use of the Epworth Sleepiness Scale to demonstrate response to treatment with nasal continuous positive airways pressure in patients with obstructive sleep apnoea

1995 • 122 citations

Nasal Continuous Positive Airway Pressure in Chronic Heart Failure with Sleep-disordered Breathing

1993 • 122 citations

Clinical Symptoms of Sleep Apnea Syndrome and Automobile Accidents

1990 • 114 citations

Long-term Effects of Treatment with Nasal Continuous Positive Airway Pressure on Daytime Lung Function and Pulmonary Hemodynamics in Patients with Obstructive Sleep Apnea

1990 • 111 citations

Screening mammography and public health policy: the need for perspective

1995 • 104 citations

Habitual snoring as a risk factor for acute vascular disease

1993 • 104 citations

Effect of Screening for Cancer in the Nordic Countries on Deaths, Costs and Quality of Life up to the Year 2017

1997 • 101 citations

DETERMINANTS OF BLOOD PRESSURE IN SNORERS

1988 • 98 citations

National Health Service breast screening programme results for 1991-2.

1993 • 96 citations

Disorders of Excessive Sleepiness

1992 • 94 citations

FALSE PREMISES AND FALSE PROMISES OF BREAST CANCER SCREENING

1985 • 93 citations

Four-Year Follow-up of Mortality and Sleep-Related Respiratory Disturbance in Non-Demented Seniors

1995 • 93 citations

24-Hour Ambulatory Blood Pressure Variability in Obstructive Sleep Apnea Syndrome

1993 • 89 citations

Report of the European Society for Mastology Breast Cancer Screening Evaluation Committee (1993)

1993 • 89 citations

Overnight Nasal CPAP Improves Hypersomnolence in Sleep Apnea

1986 • 87 citations

Daytime Sleepiness and Nasal Continuous Positive Airway Pressure Therapy in Obstructive Sleep Apnea Syndrome Patients: Effects of Chronic Treatment and 1-Night Therapy Withdrawal

1995 • 85 citations

Nation‐wide breast cancer screening in the Netherlands: Support for breast‐cancer mortality reduction

1995 • 84 citations

The Relationship Between the Severity of Sleep Apnea Syndrome and 24-h Blood Pressure Values in Patients With Obstructive Sleep Apnea

1993 • 83 citations

Daytime sleepiness after long-term continuous positive airway pressure (CPAP) treatment in obstructive sleep apnea syndrome

1992 • 81 citations

Ambulatory Blood Pressure and Left Ventricular Hypertrophy in Subjects with Untreated Obstructive Sleep Apnoea and Snoring, Compared with Matched Control Subjects, and their Response to Treatment

1994 • 81 citations

Systemic Hypertension in Snorers with and without Sleep Apnea

1992 • 78 citations

Driving Vigilance Simulator Test

1990 • 78 citations

Management of obstructive sleep apnea: Comparison of various treatment modalities

1988 • 78 citations

Nocturnal myocardial ischemia and cardiac arrhythmia in patients with sleep apnea with and without coronary heart disease

1991 • 74 citations

Is the SF 36 sensitive to sleep disruption? A study in subjects with sleep apnoea

1995 • 74 citations

A Cooperative Double-Blind Evaluation of Gastric Freezing in the Treatment of Duodenal Ulcer

1969 • 72 citations

Evening-to-Morning Blood Pressure Variations in Snoring Patients with and without Obstructive Sleep Apnea

1992 • 71 citations

Blood pressure, snoring, obesity, and nocturnal hypoxaemia

1994 • 67 citations

Ventricular Function in Snorers and Patients with Obstructive Sleep Apnea

1992 • 66 citations

Left Ventricular Ejection Fraction in Obstructive Sleep Apnea

1991 • 64 citations

Natural evolution of sleep apnoea syndrome: a five year longitudinal study

1994 • 63 citations

Nasal CPAP and weight loss in hypertensive patients with obstructive sleep apnoea.

1993 • 57 citations

Objective measurement of compliance with nasal CPAP treatment for obstructive sleep apnoea syndrome

1988 • 56 citations

The Association Between Hypertension and Sleep Apnea in Obese Patients

1993 • 53 citations

Methodological and Statistical Problems in Sleep Apnea Research: The Literature on Uvulopalatopharyngoplasty

1995 • 51 citations

Evaluation of the Effect on Breast Cancer Mortality of Population Based Mammography Screening Programmes

1994 • 50 citations

Sleepiness and Hypertension in Obstructive Sleep Apnea

1992 • 47 citations

Anthropometric characteristics, cardiac abnormalities and adrenergic activity in patients with primary disorders of sleep.

1983 • 44 citations

Systemic Hypertension in Sleep Apnea Syndrome

1990 • 41 citations

Sleep Apnea and Hypertension in Commercial Truck Drivers

1993 • 41 citations

Sleep-Related Hemodynamics and Hypertension with Partial or Complete Upper Airway Obstruction During Sleep

1992 • 39 citations

Sleep Apnea and Vigilance Performance in a Community-Dwelling Older Sample

1994 • 38 citations

Breast cancer screening as public health policy in Finland

1991 • 38 citations

Selected Cardiovascular Risk Factors in Patients With Obstructive Sleep Apnea: Effect of Nasal Continuous Positive Airway Pressure (n-CPAP)

1993 • 35 citations

The Relationship of Sleepiness and Blood Pressure to Respiratory Variables in Obstructive Sleep Apnea

1995 • 34 citations

[Psychopathological characteristics of the consequences of obstructive sleep apnea prior to and 3 months after therapy].

1993 • 28 citations

Response to CPAP and UPPP in apnea.

1990 • 27 citations

The Correlation of a Computer Simulated Driving Program with Polysomnographic Indices and Neuropsychological Tests in Consecutively Referred Patients for Assessment of Sleep Apnea

1993 • 27 citations

Haemodynamic effects of short-term nasal continuous positive airway pressure therapy in sleep apnoea syndrome: monitoring by a finger arterial pressure device

1992 • 26 citations

Sleep studies of respiratory function and home respiratory support

1994 • 23 citations

[Traffic accidents in obstructive sleep apnea patients and effect of nasal CPAP treatment].

1993 • 22 citations

Obstructive sleep apnoea and driving.

1989 • 21 citations

Snoring as a Risk Factor for Ischaemic Heart Disease and Stroke in Men

1987 • 21 citations

Cardiac arrhythmias and conduction disturbances in the sleep apnea syndrome. Prevalence and significance

1982 • 20 citations

Obstructive Sleep Apnea

1995 • 15 citations

Shortened Reaction Time During Nasal CPAP Treatment of Obstructive Sleep Apnea

1992 • 14 citations

[Daytime pulmonary hypertension in the obstructive sleep apnea syndrome].

1995 • 14 citations

SLEEP-APNEA AND RELATED CONDITIONS - SUMMARY OF A REPORT OF A WORKING PARTY OF THE ROYAL-COLLEGE-OF-PHYSICIANS

1993 • 14 citations

Cardiovascular consequences of sleep apnea.

1990 • 14 citations

Effects of nasal continuous positive airway pressure on blood pressure and body mass index in obstructive sleep apnoea

1991 • 14 citations

Sleep and the Enuresis Alarm Device

1983 • 13 citations

RESPONSE TO THE WRITTEN INVITATION IN A GYNECOLOGICAL MASS SCREENING BY CYTOLOGY ARRANGED IN HELSINKI IN 1966

1971 • 9 citations

Efectos de la presión positiva continua nasal (CPAPn) sobre la función pulmonar en pacientes con síndrome de apnea obstructiva del sueño (SAOS)

1995 • 6 citations

[Effect of suppression of apnea on arterial pressure and plasma catecholamines in normotensive patients with sleep apnea].

1994 • 3 citations

[Differences in efficiency of continuous positive pressure respiration on the diurnal somnolence of patients with sleep apnea/hypoapnea syndrome].

1995 • 1 citations